Is Sucralose Actually Bad? You're the Test Subject

You’ve may have heard sucralose is harmful. But what does the science actually say?

This week, I break down four major concerns around sucralose: glucose impairment, gut microbiome disruption, potential weight gain, and mutagenicity.  

Some studies show negative effects. Others show nothing. The truth lies in the nuance, and that's exactly what I unpack.

If you're consuming sucralose for weight management or blood sugar control, you need to understand how it really interacts with your body. I don't give you fear or fluff, just evidence.

This is just one part of the full story. Listen to the full episode if you want the complete breakdown.

00:00 Introduction to Sucralose and Its Controversies
02:15 Sucralose Origin Story
03:53 Glucose Impairment
08:33 The Gut Microbiome and Sucralose
15:24 Mutagenic Concerns and Safety of Sucralose
20:19 Weight Management and Sucralose's Role
24:21 Final Stance

References:
Glucose Impairment Bad Control Group: https://diabetesjournals.org/care/article/36/9/2530/37872/Sucralose-Affects-Glycemic-and-Hormonal-Responses
Carb Sensing from Mouth Rinsing: https://physoc.onlinelibrary.wiley.com/doi/abs/10.1113/jphysiol.2008.164285
Glucose Impairment/Gut Microbiome Better Control Group: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/shortterm-impact-of-sucralose-consumption-on-the-metabolic-response-and-gut-microbiome-of-healthy-adults/BF3E70C09C5514E4078DB3ED3E8D39B3?
Gut Microbiome Bad Control Group: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/shortterm-impact-of-sucralose-consumption-on-the-metabolic-response-and-gut-microbiome-of-healthy-adults/BF3E70C09C5514E4078DB3ED3E8D39B3?
Blautia Species Provides Benefits: https://www.nature.com/articles/s41467-024-47594-w?
More Blautia Benefits: https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202309255
Mutagenicity Study: https://www.tandfonline.com/doi/full/10.1080/10937404.2023.2213903#d1e1138
Sucralose and Weight Management: https://www.sciencedirect.com/science/article/pii/S0002916522031860?via%3Dihub

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