Operation Oroborous: How Lab-in-the-loop Turns Patient Data Into Patient Care

For years, Tempus operated in mystery—its website sparse on details while headlines announced massive funding and high-profile partnerships. The claim? AI-enabled solutions for personalized healthcare. Intrigued, I sought answers.

In this episode, Kate Sasser, PhD, Chief Scientific Officer at Tempus, shared insights into how the company uses AI to analyze unstructured clinical data to develop patient-derived organoid models for therapeutic refinement. Most exciting is their vision of an interconnected “lab-in-a-loop” system—a cycle of real-world data, biological modeling, and AI analysis.

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Produced by Bill Levine

Hosted by Jonathan D. Grinstein

Audio mixed and mastered by Jason Mack

Music provided by Artem Hramushkin

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