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April 28, 2025 39 mins

In today's episode, Melissa Kramer speaks with Dr. Soman Abraham, Professor of Pathology at Duke University, who shares insights from three decades of research into urinary tract infections. Together, they explore how the immune system responds to UTIs, why some infections become persistent or recurrent, and how a new vaccine may one day support more targeted immune responses within the bladder.


While this vaccine is still in its early stages, understanding its science can help clarify why existing treatments may fail some individuals and how future approaches could evolve.


What You'll Learn from This Episode


  • How the body responds during a UTI and why this response may not always be effective in the long term
  • Why antibiotics might clear bacteria in the urine but not reach those hiding within bladder tissue
  • How a new vaccine approach aims to activate T cells in the bladder and why this could mark a shift in future treatment strategies


Want to learn more about urinary health? Visit LiveUTIFree.com for expert articles on the latest research, or check out our YouTube channel if you prefer video format.



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