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March 4, 2025 14 mins

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This episode dives deep into infertility, exploring its biological, emotional, and cultural complexities. We discuss how understanding the multifactorial nature of infertility empowers individuals to seek support and advocate for themselves. 

• Defining infertility and its global relevance 
• Unpacking female factor infertility: ovarian, tubal, and uterine issues 
• Delving into male factor infertility and its often-overlooked role 
• Discussing the emotional challenges and societal stigma surrounding infertility 
• Examining the cultural perspectives and beliefs that shape experiences of infertility 
• Highlighting the importance of knowledge in empowering individuals facing infertility

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Speaker 1 (00:00):
Life by Dr Pat Leading innovation in fertility
excellence.

Speaker 2 (00:06):
Deep dive into reproduction with Life by Dr Pat
.

Speaker 1 (00:09):
All right, let's get ready to dive into something, a
topic that people don't reallytalk about a lot infertility.
We're doing a deep dive todaythanks to this article from a
Thai fertility clinic.
It's on their website and it'swritten by like an actual you
know, reproductive medicinedoctor.

Speaker 2 (00:29):
Oh, wow.

Speaker 1 (00:30):
And you know you might be thinking Thailand.
Yeah, what's that got to dowith me.

Speaker 2 (00:34):
Right.

Speaker 1 (00:34):
But infertility is a global thing.
It really is it affects peopleeverywhere, and so, no matter
where you live, you know,understanding the science behind
this can be really helpful.

Speaker 2 (00:45):
Yeah, it can be a really empowering thing, for
sure.

Speaker 1 (00:48):
So before we, you know, get into all the details,
what exactly is infertilitymedically speaking?

Speaker 2 (00:57):
Well, the article had a pretty straightforward
definition.
If a couple has been having,you know, regular, unprotected
sex for a year, okay, and theyhaven't gotten pregnant, then
that's what's consideredinfertility.
It's like it's not reallysaying what is wrong.

Speaker 1 (01:10):
Yeah.

Speaker 2 (01:11):
It's more of a diagnosis of what's not working.

Speaker 1 (01:13):
Right, does that make sense?
Yeah, yeah, no, that makestotal sense.
So it's not like a simple yesor no.

Speaker 2 (01:19):
Right, there's more to it.
Exactly, there's a lot more touncover, and you also have to
keep in mind that infertilitycan impact both men and women,
and a lot of times it involvesmultiple factors.
Oh, okay, it's like a puzzlewhere we have to find all the
missing pieces.

Speaker 1 (01:33):
Okay.
So let's start putting thepuzzle together.
Then, piece by piece, thearticle goes into female factor
infertility, okay, and it breaksit down by organ, you know, the
ovaries, the fallopian tubesand the uterus Right.
So let's start with the ovaries.

Speaker 2 (01:49):
Okay.

Speaker 1 (01:49):
What kind of things can go wrong there?

Speaker 2 (01:51):
So when we talk about the ovaries, there are two main
problems that can lead toinfertility.

Speaker 1 (01:55):
Okay.

Speaker 2 (01:56):
The first one is called a novulation.

Speaker 1 (01:58):
A novulation.

Speaker 2 (01:59):
Yeah, and that means that the ovaries aren't
releasing eggs.
Okay, the way they should.

Speaker 1 (02:05):
Gotcha.

Speaker 2 (02:05):
The second one is something called diminished
ovarian reserve.

Speaker 1 (02:09):
Mm-hmm.

Speaker 2 (02:10):
And that just means there are fewer eggs available
than there should be.
Yeah, Now that can be becauseof age or other factors.

Speaker 1 (02:17):
You know, it's so interesting to me how, like
things that don't seem relatedcan actually impact, you know,
our fertility.
Like the article mentions,extreme exercise.

Speaker 2 (02:26):
Yeah.

Speaker 1 (02:27):
Or even eating disorders can like disrupt
ovulation Totally.
It's just crazy howinterconnected our bodies are.

Speaker 2 (02:34):
It is.
We often think about thesethings separately, but our
bodies are complex systems.

Speaker 1 (02:38):
Yeah.

Speaker 2 (02:38):
And when we talk about diminished ovarian reserve
age isn't the only thing thatcan cause it.

Speaker 1 (02:43):
Oh really.

Speaker 2 (02:44):
Yeah, early menopause can cause it, or cancer
treatments.
Even autoimmune disorders canplay a role.

Speaker 1 (02:51):
Wow, that's a lot to think about.
Okay, so let's move on to thefallopian tubes.
Right, you know those tinypathways that connect the
ovaries to the uterus.
Yeah, what are some of theissues that can come up there?

Speaker 2 (03:02):
Well, you've probably heard of blocked fallopian
tubes.

Speaker 1 (03:04):
Yeah, I have.

Speaker 2 (03:05):
That's a big one, Because fertilization usually
happens in the fallopian tubes.
So if there's a blockage thereit's like a roadblock to
pregnancy.

Speaker 1 (03:13):
Okay, so what causes these blockages?

Speaker 2 (03:17):
So the article lists a few things.
Infections like pelvicinflammatory disease or some
STIs can lead to scarring.
Oh okay, and that can block thetubes.
And then there's endometriosis.
Have you heard of that?
I?

Speaker 1 (03:31):
have yeah.

Speaker 2 (03:31):
So that's when tissue that's similar to the lining of
the uterus grows outside theuterus and that can also create
blockages.

Speaker 1 (03:39):
Oh, wow.

Speaker 2 (03:40):
And then even scar tissue from past surgeries can
obstruct those tubes.

Speaker 1 (03:43):
Okay, so we've covered the ovaries, the
fallopian tubes.
Now get ready for this.

Speaker 2 (03:48):
Okay.

Speaker 1 (03:49):
The uterus is where things get really interesting.
I had no idea that the shape ofyour uterus could actually
matter.

Speaker 2 (03:55):
It really does.

Speaker 1 (03:56):
The fertility.

Speaker 2 (03:57):
Yeah, so the article talks about something called
congenital malformations of theuterus.

Speaker 1 (04:01):
Okay.

Speaker 2 (04:02):
And that just means that somebody's born with a
uterus that's shaped differently.

Speaker 1 (04:06):
Okay.

Speaker 2 (04:07):
And that can make it harder to get pregnant or carry
a pregnancy to term.

Speaker 1 (04:11):
Oh, wow.
So even if everything else isworking perfectly, the shape of
the uterus itself can be afactor.

Speaker 2 (04:17):
It really can.

Speaker 1 (04:17):
Yeah.

Speaker 2 (04:18):
And even if the shape is typical, there could be
other issues within the uterusthat can cause problems.
The article mentions thingslike fibroids.

Speaker 1 (04:26):
Okay.

Speaker 2 (04:27):
Adenomyosis, yeah, and polyps.

Speaker 1 (04:29):
Wow.

Speaker 2 (04:30):
All of which can interfere with implantation.

Speaker 1 (04:32):
Okay.

Speaker 2 (04:33):
Or a healthy pregnancy.
So it's like it's almost likeyou're trying to plant a seed.
It's almost like you're tryingto plant a seed in a garden
that's full of rocks and weeds,it's going to be a lot harder
for it to take root and grow.

Speaker 1 (04:43):
That's a great analogy.
Okay, so we've talked about theovaries, the fallopian tubes,
the uterus, but the article alsotalks about another important
factor, and that's the interplaybetween the mother's body and
the embryo.

Speaker 2 (04:55):
Right, because it's not just about each individual
organ.
Right it?
It's not just about eachindividual organ.

Speaker 1 (04:59):
Right.

Speaker 2 (05:00):
It's about how they all work together, so the lining
of the uterus has to beperfectly receptive for an
embryo to implant Gotcha.
It's almost like when you'repreparing soil for a seed to
take root.

Speaker 1 (05:13):
Yeah.

Speaker 2 (05:13):
It has to be just right.

Speaker 1 (05:14):
Yeah, so even if a woman's organs are all
functioning properly, if thetiming's off or the uterus isn't
receptive, it can still be achallenge to conceive.

Speaker 2 (05:25):
Exactly, and sometimes the body's own defense
mechanisms can actually workagainst pregnancy.

Speaker 1 (05:31):
Oh, wow.

Speaker 2 (05:32):
The article gave an example of antiphospholipid
syndrome.

Speaker 1 (05:35):
Okay.

Speaker 2 (05:36):
And that's when the immune system attacks the
developing embryo.

Speaker 1 (05:39):
So it's like the system that's designed to
protect us can actually get inthe way.

Speaker 2 (05:44):
It's ironic, right?
The very system that's meant toprotect us can actually become
a hurdle to creating life.

Speaker 1 (05:50):
It's just amazing how much has to go right for
pregnancy to actually occur.

Speaker 2 (05:53):
It really is.

Speaker 1 (05:54):
You know we've covered a lot about the female
side of things, but let's notforget about male factor
infertility.

Speaker 2 (06:00):
Yes, which is?

Speaker 1 (06:01):
just as common, but people don't talk about it as
much.

Speaker 2 (06:04):
No, they don't, and the article points out that men
often don't have any noticeablesymptoms.

Speaker 1 (06:09):
Oh, really yeah, yeah .

Speaker 2 (06:10):
Of infertility, so that makes testing really
crucial.

Speaker 1 (06:14):
Okay.

Speaker 2 (06:19):
So what are some of the things that can cause male
factor infertility?
Well, the article kind of putit into a few main categories
Okay.
Issues with sperm production ortransport.

Speaker 1 (06:25):
Okay.

Speaker 2 (06:26):
Hormonal imbalances and genetic factors.

Speaker 1 (06:29):
Okay, so there's a pretty wide range of potential
problems there too.

Speaker 2 (06:33):
There really is.
So it can be anything fromsomething called varicocele.

Speaker 1 (06:36):
Okay.

Speaker 2 (06:36):
Which is basically like having varicose veins near
the testicles.

Speaker 1 (06:40):
Varicose veins.

Speaker 2 (06:41):
Yeah, like those bulging veins that you see on
people's legs sometimes.
Uh-huh that, but near thetesticles.
That's what a varicocele is.

Speaker 1 (06:47):
Okay, so that's one possibility.
What else?

Speaker 2 (06:51):
It can also be injuries, certain infections
like mumps that affect thetesticles.
Lifestyle factors like smokingalcohol, even past cancer
treatments.
It's a pretty long list.

Speaker 1 (07:03):
Wow.
So we've learned that both maleand female infertility can come
from a lot of different factors.

Speaker 2 (07:09):
Definitely.

Speaker 1 (07:10):
This is a really complex topic.

Speaker 2 (07:11):
It is.

Speaker 1 (07:12):
But knowing all of this, it kind of empowers us
right.

Speaker 2 (07:14):
Yeah, it does.

Speaker 1 (07:15):
It gives us the knowledge to ask questions and
advocate for our own health.

Speaker 2 (07:20):
And that's something that the article really
emphasized the importance ofunderstanding the root cause of
infertility in order to find thebest treatment.
It's not about placing blame.
It's about getting the rightinformation to make informed
decisions.

Speaker 1 (07:35):
Yeah, it's like solving a mystery, huh.

Speaker 2 (07:36):
Yeah.
We've uncovered so many cluesin this deep dive into
infertility right and you know,like we said, it's rarely a
simple issue no, it's more likea detective story it is you know
, piecing together all thedifferent factors to figure out
what's going on and, as thearticle points out,
understanding the why is reallyimportant, yeah, for finding

(07:57):
effective treatment that is sucha key point.

Speaker 1 (07:59):
you know this article .
It doesn't really get intospecific treatments, but it
makes it really clear thatinfertility is treatable in a
lot of cases.
But the first step is always adiagnosis, figuring out why a
couple is struggling to conceive.
That's the foundation forchoosing the right treatment
approach.
Right, it's like you wouldn'ttreat a headache without knowing
, you know, is it from stress,is it a sinus infection, or

(08:22):
something else entirely Exactly,and that's where working with a
fertility specialist can be sohelpful.

Speaker 2 (08:27):
Yeah, they can run tests, evaluate both partners
and then kind of help guide youtoward the best course of action
.

Speaker 1 (08:35):
So it sounds like knowledge is power.
When it comes to infertility,it really is, even though you
know we've only scratched thesurface.
Just understanding the basicscan really help someone ask the
right questions and advocate forthemselves.

Speaker 2 (08:49):
Absolutely.
And you know, while thisarticle focuses mainly on the
biological side of infertility,I think it's also important to
remember the emotional impacttoo, which can be huge yeah yeah
, you're so right.

Speaker 1 (08:59):
The emotional aspect is something that the article
doesn't really touch on yeah butit's a huge part of the
experience.
Infertility can be sochallenging emotionally and it
can really affect individualsrelationships, even how people
see themselves that's true.

Speaker 2 (09:15):
There's often a lot of shame and secrecy surrounding
infertility, and that can makeit even harder to cope.
There's this unspoken pressureto have children.

Speaker 1 (09:23):
Yeah.

Speaker 2 (09:24):
And when it doesn't happen easily, people can feel
like they've failed in some way.

Speaker 1 (09:28):
Yeah, it's like they're carrying this invisible
burden and I think, like thecultural expectations and
societal pressures around havingchildren can definitely add
another layer of complexity.

Speaker 2 (09:40):
I agree.
We need to create spaces wherepeople feel comfortable talking
about these challenges.

Speaker 1 (09:45):
Yeah.

Speaker 2 (09:46):
And seeking support and finding healthy ways to cope
.
It's not just about the science, it's about the whole human
experience.

Speaker 1 (09:53):
You're right, and if you're listening to this and
infertility is something you'refacing, you're not alone.
You really aren't.
There are resources available,and just seeking support can
make such a big difference.

Speaker 2 (10:03):
Absolutely, and even though this deep dive is coming
to an end, your journey oflearning and exploration doesn't
have to.

Speaker 1 (10:10):
Okay, so we've covered a lot today the medical
definition of infertility, thecomplexities of both female and
male factors, the emotionalweight that often comes with it.
But before we wrap up, I wantto leave our listener with a
final thought to think about.
The article we've beendiscussing comes from a Thai
fertility clinic, and it got methinking about how different
cultures view infertility.

Speaker 2 (10:32):
That's a fascinating question.
You know, this article doesn'treally get into cultural
perspectives.

Speaker 1 (10:38):
No.

Speaker 2 (10:39):
But it's definitely something worth considering.

Speaker 1 (10:41):
Yeah.

Speaker 2 (10:41):
Infertility is such a sensitive topic and you know
cultural norms, beliefs,expectations.

Speaker 1 (10:47):
Right.

Speaker 2 (10:48):
Those can all play a role in how people experience
and cope with it.

Speaker 1 (10:51):
Exactly, In some cultures there might be a really
strong stigma.

Speaker 2 (10:54):
Oh yeah.

Speaker 1 (10:55):
Attached to infertility, which can lead to
people feeling isolated orashamed, but in others there
might be more open conversationsand support systems in place.

Speaker 2 (11:04):
That's true, and even access to health care and
fertility treatments.
That can vary so much dependingon where you live and what
resources are available.

Speaker 1 (11:12):
It's true.
So it's not just about theindividual's journey, right,
right, it's also about thebroader social context in which
that journey unfolds.

Speaker 2 (11:19):
It always comes back to the bigger picture, and so
this raises a question for ourlistener how does your own
culture view infertility?
Are there any like prevailingbeliefs or attitudes that shaped
your understanding of thisissue?

Speaker 1 (11:36):
That's such a great question to think about, and it
reminds us that, even though thescience of infertility is
universal, the human experienceof it is deeply personal and
often intertwined with thosecultural factors.

Speaker 2 (11:49):
It is.
I think that's a perfect placeto end on.
We've gone from like thecellular level of eggs and sperm
to the societal perceptions ofinfertility.
Right Just shows howmultifaceted this topic really
is.

Speaker 1 (12:01):
Well, it's been quite a journey.
We've learned so much in thisdeep dive into the world of
infertility.
We unpacked the biologicalcomplexities, explored the
emotional impact and eventouched on the cultural
dimensions.
I hope this has left you, ourlistener, feeling more informed,
empowered and maybe even alittle bit curious to learn more
.

Speaker 2 (12:18):
And remember this is just the beginning of the
conversation.
Yeah, there's so much more toexplore and understand about
infertility, both personally andsocietally.

Speaker 1 (12:28):
So keep asking questions, keep learning and
keep the conversation going.
Thanks for joining us on theDeep Dive.

Speaker 2 (12:35):
Yeah, it really makes you think how something so
personal can also be like, soconnected to cultural beliefs
and societal norms.
Right, you know, it makes yourealize that infertility isn't
just a medical issue.
Right, it's a human experience.

Speaker 1 (12:51):
Yeah.

Speaker 2 (12:52):
That's shaped by the world around us.

Speaker 1 (12:53):
It really is, and it highlights how important it is
to talk about infertility.

Speaker 2 (12:57):
Yeah.

Speaker 1 (12:58):
You know, openly and honestly, both in our own
communities and on a largerscale.

Speaker 2 (13:02):
Right.

Speaker 1 (13:03):
The more we talk about it.

Speaker 2 (13:04):
Yeah.

Speaker 1 (13:04):
The more we can break down those stigmas.

Speaker 2 (13:06):
Right.

Speaker 1 (13:07):
And support people who are struggling.

Speaker 2 (13:09):
I totally agree and I think this deep dive has been a
good step in that direction.
You know we've covered so muchthe biology of conception, right
the emotional side ofinfertility, the cultural
perspectives.
It's been quite a journey and Ihope our listener feels
empowered by what we've talkedabout today, yeah.
Empowered to ask questions,seek support and advocate for

(13:30):
themselves.

Speaker 1 (13:31):
Absolutely.

Speaker 2 (13:32):
Knowledge is power right, it really is.

Speaker 1 (13:34):
And understanding infertility can make a huge
difference.

Speaker 2 (13:37):
It can, yeah, and this is just the start.

Speaker 1 (13:40):
Yeah.

Speaker 2 (13:40):
There's so much more to learn about this topic, and
this is just the start there'sso much more to learn about this
topic.
That's true Both personally andas a society Well to our
listener.

Speaker 1 (13:46):
we encourage you to keep you know, keep digging,
keep asking questions, keep theconversation going.

Speaker 2 (13:52):
That's right.

Speaker 1 (13:55):
Thanks for joining us on the Deep Dive Leading
Innovation Fertility ExcellenceLife by Dr Pat Leading
innovation in fertilityexcellence.
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