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June 16, 2025 114 mins

In this deep-dive discussion, Dr. Michael D. Roberts, Professor at Auburn University and Director of the Nutrabolt Applied and Molecular Sciences Lab, joins Drs. Cody Haun and Daniel Lawson (and Dr. David Hardin) for an in-depth exploration of muscle hypertrophy, aging, anabolic hormones, and molecular adaptation.

We cover:

• Myonuclear permanence & muscle memory

• Sarcoplasmic vs. myofibrillar hypertrophy

• High-volume training & edema

• Testosterone, anabolics, and clinical applications

• Ribosome biogenesis & genetic variability in response

• Aging, epigenetics, omics, and the future of muscle research


If you're interested in the science behind how and why muscle grows—and what that means for health, longevity, and performance—this episode is for you.

Fitomics Resources:

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https://www.instagram.com/drdanlawson/

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Website: https://fitomics.org

Research Labs Insider: https://fitomics.org/researchlabsinsider

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Nutrition Insiders: https://www.fitomics.org/nutrition-insiders

03:06 The Nutrabolt Lab and Research Funding

05:53 Exploring Muscle Biology and Aging

12:04 The Importance of Muscle in Longevity

14:55 Translating Animal Research to Human Studies

18:15 The Role of Muscle in Metabolic Health

21:02 The Impact of Muscle Mass on Mortality

27:18 The Future of Muscle Research and Interventions

36:48 The Role of Testosterone in Health and Fitness

42:51 Myonuclear Permanence and Muscle Memory

45:43 Hypertrophy: Myofibrillar vs. Sarcoplasmic

54:38 Sarcoplasmic Hypertrophy: Evidence and Controversies

01:16:46 Understanding Muscle Gain Variability

01:18:13 Exploring Ribosome Biogenesis and Satellite Cells

01:32:26 The Role of Advanced Sequencing in Muscle Research

01:39:04 Practical Applications of Molecular Insights

01:47:57 Future Directions in Muscle Research

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