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September 3, 2025 50 mins

In this episode, I’m joined by Sage King — a Naturopath, Nutritionist, educator, and advocate shaking up the world of inclusive reproductive healthcare. Sage offers evidence-based, trauma-informed naturopathic care with a deep commitment to creating safe, accessible spaces for LGBTQIA+, neurodivergent, and sex worker communities.

Sage brings a broad, nuanced lens to complex health topics, and today we’re diving into one that’s often overlooked: the connection between hormones and histamine. If you’ve experienced symptoms like PMS, migraines, or anxiety that don’t seem to fit the usual hormonal picture, this episode may give you the missing piece of the puzzle.

In this episode, we chat about:

  • What histamine is and its roles beyond allergic reactions
  • How histamine is produced and regulated in the body
  • Histamine intolerance, sensitivity, excess and MCAS
  • Common symptoms of histamine issues and why they’re often misdiagnosed
  • The gut microbiome’s influence on histamine levels
  • How oestrogen and histamine interact
  • The role of histamine in reproductive health conditions
  • Whether to target histamine, oestrogen, or both in treatment
  • The pros and cons of antihistamines
  • Testing challenges around histamine intolerance
  • How diet, supplements and herbs can help
  • Practical tips to manage symptoms while waiting for support
  • Sage’s #1 piece of advice for navigating hormonal and histamine issues


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Disclaimer: The information provided on Gutsy Talks is for education and informational purposes only. It is not provided nor intended to substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event you have questions or concerns about your health.

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