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May 14, 2024 15 mins

In this episode, Dr. Jess Pelletier speaks with Dr. Emmanuel Effa about typhoid fever.

Take-Home Points:

  • Typhoid fever is endemic in settings with water and sanitation issues
  • In other places, it is more commonly imported from overseas when people visit endemic areas
  • Typically, infected people present with varying degrees of fever, fatigue, headaches, abdominal pains and constipation/diarrhea. It can run a severe course that leads to death
  • Diagnosis is based on clinical features and cultures of bone marrow, blood, stool or urine
  • Treatment is guided by local protocols dependent on antimicrobial sensitivity patterns
  • Vaccines are available and are reasonably effective.
  • Overall, promoting access to safe water ensuring adequate sanitation; promoting hygiene among food handlers and typhoid vaccination are effective in preventing typhoid fever

You can view the full show notes and references here: https://docs.google.com/document/d/15yGRZV8UpQEKcFIwSFnCOGEl1uE77wlFP3T7tpm-YFc/edit?usp=sharing

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