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May 6, 2025 14 mins

Rhabdomyolysis may start in the muscles—but without fast nursing intervention, it can spiral into electrolyte imbalances, kidney failure, and life-threatening arrhythmias. In this episode, Dr. Morgan Taylor, DNP, CPNP, CCRN, breaks down the cascade of events that occurs when muscle cells break down and release their contents into the bloodstream. 

From dark “cola-colored” urine to dangerously high potassium levels, Dr. Taylor shares the classic signs of rhabdo, the key labs to monitor, and a real-life case that underscores how fast things can escalate. Learn the step-by-step interventions to protect the kidneys, stabilize the heart, and prevent deadly complications. Plus, we’ll walk through a high-yield NCLEX-style question to solidify your knowledge. 

Topics discussed in this episode: 

  • What rhabdomyolysis is and why it’s a medical emergency 

  • Muscle cell breakdown and the release of CK, myoglobin, potassium, and phosphate 

  • Classic signs: tea-colored urine, weakness, muscle tenderness, and electrolyte abnormalities 

  • A real case of rhabdomyolysis in a college athlete 

  • Managing hyperkalemia: calcium gluconate, insulin, and dextrose 

  • Breaking down a high-yield NCLEX question on EKG changes in rhabdomyolysis 

This episode is packed with critical nursing actions and clinical red flags to help you manage rhabdomyolysis like a pro. Tune in now to sharpen your skills and prep for both the NCLEX and real-world emergencies! 

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