EP 8 - Diabetes Insipidus

Diabetes insipidus (DI) is a serious disorder of water balance that can lead to extreme fluid loss, electrolyte imbalances, and life-threatening complications. In this episode, Dr. Morgan Taylor, DNP, CPNP, CCRN, breaks down the pathophysiology of DI, explains the difference between neurogenic and nephrogenic causes, and shares a real-life case where fluid imbalance spiraled into a medical emergency. 

Learn how to recognize the classic signs of diabetes insipidus, why desmopressin is life-saving in some cases—but dangerous in others—and what red flags signal a need for immediate nursing intervention. Plus, Morgan walks through a high-yield test question to help you master this tricky topic for both the NCLEX and clinical practice. 

Topics discussed in this episode: 

• What diabetes insipidus is (and what it’s not) 

• The role of antidiuretic hormone (ADH) in fluid balance 

• Causes of neurogenic vs. nephrogenic DI 

• Classic signs: excessive urination, thirst, and hypernatremia 

• A real case of post-op neurogenic DI 

• Nursing priorities: desmopressin therapy, fluid replacement, and sodium monitoring 

• The dangers of overcorrection and how to spot severe hyponatremia 

This episode is packed with high-yield clinical content that will sharpen your critical thinking and help you feel confident managing fluid and electrolyte imbalances. Tune in now! 

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