AI on the Blockchain: Building a Safer Digital Future with DecideAI

Jesse Glass, Lead AI Researcher at DecideAI, steps into the spotlight at a moment when the stakes for AI and data privacy have never been higher. As AI systems race ahead, so do the risks—exposing sensitive data in ways most current tech simply isn’t built to defend. Enter the “zero trust” philosophy: a world where blockchain’s decentralized backbone eliminates the need for faith in third-party APIs, external hosts, or shadowy identity layers.

In this episode, Jesse unpacks why trustless, decentralized systems are essential as AI moves into high-stakes territory—from medical diagnostics to supply chain risk management and data-sensitive language models. We’ll explore whether true AI-on-blockchain is finally within reach, or if the real magic happens when AI’s reasoning power teams up with blockchain’s immutable ledgers, leveraging oracles and agentic systems to keep data secure.

Jesse shares his journey to DecideAI, the company’s vision for a safer, smarter digital future, and which blockchains are best suited for this next frontier. We’ll dig into the power of zero-knowledge proofs, strategies to outsmart Sybil attacks, and how the privacy-versus-verification debate is shaping the evolution of Ethereum and its rivals.

If you’re curious about the future of AI, privacy, and the architecture of a truly trustless internet, this is the conversation that connects all the dots—and then some

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