If you’re a woman in your 40s or 50s, wondering what fresh hell this is, you’re in the right place. Welcome to The Hormone Shift Show, a podcast about “the shift,” for women in the shift. Hosted by Leslie Duffy, RN, Functional Wellness Practitioner, and Life Coach for women 40+, this show delivers a holistic (but not crunchy) take on what’s happening in your body, mind, and life during perimenopause and beyond. It’s for smart, health-conscious women who are motivated to feel better but are tired of the noise, confused by vague advice from pseudo-experts, and frustrated that even their doctor doesn’t seem to know what to do. They’re not looking for a quick fix, another prescription, or one more appointment that ends with “you’re fine.” Each week, Leslie brings clinical insights, lifestyle support, and honest conversation to help you feel physically and emotionally better, with real solutions designed for this season of life. You’ll also hear monthly guest interviews on topics like metabolism, mood, stress, movement, longevity, parenting, relationships, money, and more. If you’ve been looking for a podcast with midlife medicine you can actually understand (practical insights, science-ish explanations, and the occasional “okay, same” moment), you’re in the right place. This podcast brings clarity, honesty, and a functional medicine lens to a season of life most women are still left guessing about. You’ll walk away feeling informed, supported, and a little more sane. If you would like to reach out to Leslie and learn about her programs, visit her website: https://leslieduffycoaching.com/ or message her on Instagram at: @LeslieDuffyCoaching
“Anxiety in perimenopause isn’t about your husband or your job; it’s your hormones.” - Leslie Duffy
While it would be easy to think your increased anxiety or irritability is a result of your workload, your partner, or the state of the world, that might not be the case. Here’s the truth: in perimenopause, shifting estrogen and progesterone is remodeling your brain and making you more vulnerable to anxiety tha...
“Stress is the enemy of self-control, and your cravings are not about willpower.” – Leslie Duffy
If you’ve ever found yourself halfway through a bag of chips or surrounded by Oreo crumbs, wondering what just happened, you’re not alone. Your cravings aren’t a sign of low willpower or weakness; they’re driven by shifts in estrogen and dopamine, and amplified during perimenopause and menopause. That “treat your...
“You can’t lose weight if your life is a dumpster fire.” – Leslie Duffy
If you’ve been hitting the gym, counting the calories, and still can’t budge the numbers on the scale, here’s the truth: it’s probably not what you’re eating. In midlife, fluctuating estrogen levels make our bodies more sensitive to stress, and we can’t handle the stress response as well as we used to. Your overscheduled life, that cowo...
“Midlife isn’t a crisis, it’s a turning point. Your comeback starts here.” – Leslie Duffy
If you’re a woman over 40 and you barely recognize yourself in the mirror… your energy’s in the tank, your emotions are all over the place, and you’re wondering what happened to the “you” you used to be, you’re not alone. And you’re not broken.
I’m Leslie Duffy, a registered nurse, life coach, and certified functional ho...
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