The Most Interesting Thing in A.I.

The Most Interesting Thing in A.I.

A podcast series examining how AI is reshaping our world. Hosted by Nicholas Thompson, each episode features a conversation with a leading thinker who offers a fresh perspective on the far-reaching ethical, economic, and social implications of this technology.

Episodes

AI Optimism - with Nicholas Thompson and Kevin Kelly

June 18, 2025 • 37 mins
What happens if we get AI right? In this episode, Nicholas speaks with Wired co-founder Kevin Kelly about AI’s potential to positively impact the future of humanity. Featured Guest: Kevin Kelly, co-founder of Wired Learn more about your ad choices. Visit megaphone.fm/adchoices
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Pharma's Future - with Nicholas Thompson, Diogo Rau and Dan Priest

June 11, 2025 • 41 mins
How is AI shaping the future of healthcare? In this episode, Nicholas speaks with Eli Lilly’s Diogo Rau about how AI is making it easier and faster to find life-saving drugs, and PwC Chief AI Officer Dan Priest about how the technology will transform healthcare experiences for patients in the next decade. Featured Guests: Diogo Rau, Executive Vice President and Chief Information and Digital Officer at Eli Lilly & Dan Priest, Chi...
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Making Music With AI - with Nicholas Thompson and Holly Herndon

June 4, 2025 • 36 mins
AI is transforming the creative landscape, opening up possibilities for a new generation of artists. In this episode, Nicholas speaks with experimental musician and AI artist Holly Herndon about the intersection of human and machine creativity. Featured Guest: Holly Herndon, co-founder of Spawning Learn more about your ad choices. Visit megaphone.fm/adchoices
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Outsourcing Thought - with Nicholas Thompson and Nita Farahany

May 28, 2025 • 43 mins
AI is reshaping not just what we think but how we think. In this episode, Nicholas speaks with neuroethicist and legal scholar Nita Farahany about AI's impact on human cognition. Featured Guest: Nita Farahany, Robinson O. Everett Distinguished Professor of Law & Philosophy at Duke University and founding director of the Duke Initiative for Science & Society Learn more about your ad choices. Visit megaphone.fm/adchoices
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Ethical Machines - with Nicholas Thompson and Audrey Tang

May 21, 2025 • 47 mins
In the right hands, AI can strengthen human collaboration and civic engagement. In this episode, Nicholas speaks with Taiwanese politician and programmer Audrey Tang about how the technology can be used to enhance democratic structures. Featured Guest: Audrey Tang, Taiwan's Ambassador-at-Large for Cyber Affairs Learn more about your ad choices. Visit megaphone.fm/adchoices
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A Different Approach to AI - with Nicholas Thompson and Gary Marcus

May 14, 2025 • 44 mins
Despite the rapid advancements, today’s LLMs are far from infallible. In this episode, Nicholas speaks with author, cognitive scientist, and entrepreneur Gary Marcus, about the ways in which  current AI models fall short, and what Marcus believes is the better path forward. Featured Guest: Gary Marcus, Cognitive Scientist, Author, and AI Entrepreneur Learn more about your ad choices. Visit megaphone.fm/adchoices
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Season 2 Trailer

May 12, 2025 • 1 min
A podcast series examining how AI is reshaping our world. Each episode features a conversation with a leading thinker who offers a fresh perspective on the far-reaching ethical, economic, and social implications of this technology. Learn more about your ad choices. Visit megaphone.fm/adchoices
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Drawing with Robots - with Nicholas Thompson and Sougwen Chung

January 22, 2025 • 30 mins
While many in the creative world approach AI with hesitation or fear, others embrace it as a collaborator, using it to expand the possibilities of artistic expression. This episode examines how AI is reshaping creativity, from enhancing traditional methods to challenging conventional notions of authorship, offering a glimpse into a future where humans and machines create together. Featured Guest: Sougwen Chung, Artist and Founder ...
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Sustainable Solutions - with Nicholas Thompson, Scott Likens and Heather Horn

January 15, 2025 • 30 mins
The environmental cost of AI is significant, but so is the technology’s potential to help develop new sustainable solutions. This episode examines how AI may guide us to promising breakthroughs in energy creation, and how organizations can leverage the technology to track emissions, optimize resource usage, and support corporate ESG goals, offering insights into how businesses can embrace technology to drive meaningful environmenta...
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Incremental vs. Exponential - with Nicholas Thompson and Andrew Ng

January 8, 2025 • 29 mins
AI is advancing at an unprecedented pace. Some experts are convinced that the world as we know it will change dramatically, while others anticipate a more steady evolution. This episode dives into the debate, separating hype from realistic predictions about the future of AI. Featured Guest: Andrew Ng, Founder of DeepLearning.AI and Adjunct Professor at Stanford Learn more about your ad choices. Visit megaphone.fm/adchoices
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Staying Competitive - with Nicholas Thompson and Dan Priest

December 18, 2024 • 26 mins
AI is no longer just a tool for experimentation—it’s becoming a foundational technology that’s reshaping how businesses operate. This episode describes how companies are embedding AI into their products and services, exploring its potential to boost efficiency, to personalize customer experiences, and to potentially alter entire industries. From early adoption strategies to the rise of agent-based AI, the conversation highlights ho...
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Deepfakes and Deception - with Nicholas Thompson and Eva Galperin

December 11, 2024 • 25 mins
From voice-cloning scams to the creation of non-consensual nude imagery, the malevolent use of artificial intelligence poses myriad risks to truth, privacy, and personal safety. Cybersecurity expert Eva Galperin discusses how artificial intelligence is transforming digital threats, and how we need to work together to mitigate risk, preserve factual integrity, and shift social norms in the digital realm. Featured Guest: Eva Galperi...
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Machine Consciousness - with Nicholas Thompson and Geoffrey Hinton

December 4, 2024 • 24 mins
What if the most advanced AI models could think and respond in a way that felt like a human consciousness? How might that transform our understanding of intelligence itself? Some of the leading AI scientists believe that a super-intelligent form of this technology is only five to ten years away. This episode explores the idea of AI consciousness and delves into how the act of dreaming is connected to neural networks in unexpected w...
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