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September 24, 2025 53 mins

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Wall Street vet turned health optimizer Hunter Ziesing (Co-Founder, Longevity Health; ex-Head of Partnerships, Paceline) joins SUPERHUMAN to unpack how to make prevention stick: AI-driven care, behavior gamification, CGMs, DEXA, VO₂ max, and what truly moves the needle. We also hit data privacy, insurer incentives, blockchain for clinical trials, supplement skepticism, and why Zone 2 + strength training beats most hacks. Rapid, no-fluff, insanely actionable.

What you’ll learn:

  • How to operationalize preventative care with AI + clinical oversight
  • Incentives that actually change health behavior (beyond wearables hype)
  • The test stack that matters (bloods, DEXA, VO₂, sleep) and what to skip
  • Supplements: when labs say “yes” vs. snake oil
  • Zone 2, VO₂ max, and cycling as lifelong “antidepressant” cardio
  • The path to scalable, personalized longevity programs

Guest
Hunter Ziesing — Co-Founder, Longevity Health; advisor; competitive cyclist

Links

Chapters
00:00 Intro + why longevity now
03:40 Behavior change that works (Paceline lessons)
09:25 The real test stack & price reality
16:30 AI coach: regulation, safety, and “driverless doctor”
24:10 Food environment, incentives, and outcomes
31:45 Data privacy, wearables, and insurance
36:20 Crypto, trials, and owning your health data
41:55 Supplements vs. labs: what’s worth it
47:30 Cycling, Zone 2, VO₂ max, and aging strong
56:10 Favorite thinkers (Attia, Hyman, Johnson)
1:02:40 Closing takeaways

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