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June 10, 2025 65 mins

You’ve been told to eat clean, but what if your “healthy” foods are wrecking your gut, crushing your hormones, and aging you faster? This episode exposes the nutrient-depleted truth behind modern diets, soil erosion, and why regenerative farming might be the key to reversing chronic disease, boosting mitochondria, and rebuilding your biology from the ground up. 


Watch this episode on YouTube for the full video experience: 

https://www.youtube.com/@DaveAspreyBPR 


Host Dave Asprey sits down with Dr. Josh Axe, a trusted pioneer in functional medicine, bestselling author, and co-founder of Ancient Nutrition. Dr. Axe bridges the gap between biblical farming, ancestral nutrition, and modern science to explain how your food and even your supplements may be harming your human performance, digestion, and brain health. With clinical insights, personal stories, and science-backed tools, he shares what to eat instead if you want real longevity, energy, and healing. 


They dig into the collapse of soil nutrients, how monocropping damages the microbiome, and why organic food standards may be outdated. You’ll learn how regenerative agriculture rebuilds the earth and your gut, and why biohacking starts with dirt, not pills. Plus, they explore the hormonal chaos caused by seed oils, plastics, blue light, sleep disruption, and even birth control, especially in relation to testosterone loss in men and women. 


This episode also touches on biblical nutrition, fasting cycles, natural nootropics, testosterone-supporting peptides, the dangers of synthetic vitamins, and the future of real-time self-quantification. From poop-powered farming to smarter sourcing, it’s a wild ride into how food, faith, and farming affect every part of your biology. 


This is essential listening for anyone serious about biohackingneurohackinglongevityUpgrade LabsDanger CoffeeSmarter Not Harder, and understanding the real root of disease and dysfunction. 


You’ll Learn: 

• Why regenerative farming beats “organic” for health and the planet 

• How depleted soil is linked to hormone imbalances and chronic disease 

• What birth control is doing to testosterone, fertility, and mitochondrial health 

• Why your supplements may just be “expensive pee” 

• The truth about biblical farming and why dirt still matters 

• How to support testosterone naturally with diet, peptides, and habits 

• Why sleep optimization, mineral balance, and circadian alignment are key for healing 


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. 


Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. 


 

SPONSORS: 

- BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.  

- Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order 


Resources:  

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ 

• Josh Axe’s Website https://thehealthinstitute.com/ 

• Josh Axe’s Instagram: https://www.instagram.com/drjoshaxe/?hl=en 

Danger Coffee:


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