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November 11, 2025 35 mins

Around 25 years ago, Ardem Patapoutian set out to investigate the fundamental biology behind our sense of touch. Through a long process of gene elimination, he identified a class of sensors in the cell membrane that turn physical pressure into an electrical signal. He changed the game in the field of sensation and perception, and in 2021 shared the Nobel Prize in Physiology or Medicine for his work. 

He joins Host Flora Lichtman to talk about his research, the odd jobs he worked along the way, and how he found a sense of belonging in science.

Guest: Dr. Ardem Patapoutian is a professor and the Presidential Endowed Chair in Neurobiology at the Scripps Research Institute in La Jolla, California. 

Transcripts for each episode are available within 1-3 days at sciencefriday.com.

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