November 26, 2025 • 24 mins
(November 26, 2025)
When home sellers set prices too high, they’re paying for it. Most modern dogs have ‘detectable’ wolf ancestry, scientists say. Dr. Jim Keany, Chief Medical Officer at Dignity Health St. Mary Medical Center in Long Beach, joins The Bill Handel Show for 'Medical News'! Dr. Keany talks with Bill about a bird flu strain never before seen in humans until now and scientists issuing a warning after discovering overlooked factor that can cause Parkinson’s.
See omnystudio.com/listener for privacy information.
Mark as Played
Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:00):
You're listening to Bill Handle on demand from kf I
am six forty.
Speaker 2 (00:07):
I am six forty Bill Handle here on a Wednesday morning, Hopday,
November twenty sixth, tomorrow being Thanksgiving. Neil Savedra is silly
in for me, as he does every Thanksgiving, and he
will be there tomorrow and Friday, and then we go
back to regularly scheduled broadcast. And I don't know if
(00:31):
I'm going to do it on Saturday, handle on.
Speaker 1 (00:34):
The law, but.
Speaker 2 (00:37):
If not, what we what we'll do is I'll run
a show and I'll pretend that I'm there even though
I'm not there, to fool you guys into thinking I
am there. See. One of the things I do on
Tuesdays and Thursdays is I take these phone calls, as
you know, off the air for future broadcast. This is
what it's about. So Saturday, you have to guess Bill
(01:00):
there or not.
Speaker 1 (01:01):
Oh, that's a contest.
Speaker 2 (01:02):
We should give something away for people that guess correctly,
So flip a coin. But don't worry about it. If
I'm not there, You'll think I'm there. So everything is cool. Damn,
do I do a good job on this broadcast, don't
I damn straight, Okay, I happen to be a sort
of a fanatic about real estate prices.
Speaker 1 (01:23):
I just it's the thing for me.
Speaker 2 (01:25):
I just happened to talk about and enjoy, literally enjoy,
and in my head and with others get into prices.
And since I just bought my home, we talked prices,
since I sold the Persian Palace, I'm particularly interested in
home prices these last days. So let's talk about you.
(01:45):
If you're serious about selling your home, you probably have
to drop the price. Overpriced houses are languishing on the market.
Buyers are continued to be deterred by elevated mortgage rates.
Speaker 1 (01:58):
There's no longer three percent money.
Speaker 2 (02:01):
Economic uncertainty during COVID and everybody was staying at home,
and all of a sudden.
Speaker 1 (02:06):
Houses go up in value right after that.
Speaker 2 (02:11):
Sellers actually optimistically priced their homes based on sales from
the twenty from the twenty twenties, right from five years ago,
when there was three percent money, when there were plenty
of houses available and people were snamping them up. Jessica Lotts,
who's deputy chief Economists at the National Association of Realtors,
(02:33):
who's really on top of that, tells owners. If you
are going to sell, calibrate your asking price by looking
at what comparable houses are in the neighborhood that sold
for the last month or so. Do not go back
five years. That ain't happening. What you want to do
(02:53):
is what happened the last couple of months. Twenty percent
of listings in October had a price cut, according to
realtor dot com. That's a lot of homes that are
price cut because we're used to having homes that are
just snapped up.
Speaker 1 (03:09):
Well that's not the case anymore.
Speaker 2 (03:11):
And by the way, the twenty percent is twice as
high as when the price is soared during the pandemic.
And what happens if you set the price too high, Well,
it doesn't sell, It drags on and you have to
lower the price. After a period of several months, you
realize I can't get the price, so I now have
(03:32):
to lower it. Listings that sold after the price reduction
spend five times as many days on the market as
the average home that was listed correctly.
Speaker 1 (03:43):
Now keep in mind, I mean what does that mean.
Speaker 2 (03:45):
Okay, you have listed your house and it's too expensive,
and then you reduce the price. Well, even after the reduction,
It takes five times longer to sell your house. If
the home is priced directly, they also get one hundred
percent of their asking price almost immediately. When I bought
(04:05):
my house here in Orange County, I paid market for
the price I paid what was basically listed. I got
a little bit of a discount, but not much. And
that's if it was priced correctly, and a house across
the street sold and a house down the street sold
very quickly.
Speaker 1 (04:26):
They were priced correctly in my neighborhood.
Speaker 2 (04:29):
If the listing has been around on the market for
a month or more, what happens is home buyers are
now talking about negotiating a discount after three months if
your house is on the market. Usually prices dropped by
five percent after a year, and there are plenty of
homes that sit there for a year when the price
way too high. Then that reduces more than twelve percent.
(04:53):
And keeping on to a house that is too high
priced for period of many months or a year, imagine
what it costs you. If you already moved, you're screwed.
You have an empty house and is costing you a fortune.
But even you have to stay well if you're selling
it based on if you're buying it based on another house,
or selling it based on a property that you've bought
(05:14):
or intend on buying, you're holding on You can't do that.
So today it's buyers who have time, they have leverage,
and they're making offers under.
Speaker 1 (05:25):
The listing price. Remember the stories.
Speaker 2 (05:27):
I mean, people were buying houses for a period of
time site unseen because there was such a ridiculous demand
for housing, and they were offering prices that were way higher,
I mean over market. So a house to be listed
at seven hundred thousand dollars, let's say, quite often it
(05:47):
went for eight hundred eight point fifty.
Speaker 1 (05:50):
That's what it used to be.
Speaker 2 (05:52):
Not that way any longer. You have to be realistic
about it when listing a price. And just to tell
you how crazy I am about looking at housing prices,
Lindsay spent a couple of days in Las Vegas and
she brought home usually you know yet little knickknacks magnet
for the mirror, that sort of thing. She brought home
(06:14):
a booklet of homes that were listed. You've seen those
home magazines, and I go through it. Okay, this one,
oh my god, this isn't worth two million dollars. Look
at this, this is what they offer, this is what
they don't.
Speaker 1 (06:29):
So having been that way, now an easy way.
Speaker 2 (06:32):
Of course of selling your home, and I do commercials
as you know, for direct buyers dot com. None of
that happens. I mean that just disappears instantly. But there
are many ways to sell your house, as you know.
Speaker 1 (06:46):
There you go.
Speaker 2 (06:47):
And one fun story about dogs, modern dogs and how
they have well connected to wolves.
Speaker 1 (06:56):
And we know that dogs.
Speaker 2 (06:59):
Came from wolves, I mean that's sort of a given.
And then and interbreeding of wolves and dogs and over
the thousands and thousands of years, I mean going back
maybe thirty thousand years, you have the modern dog now.
But there is now a science science has proven that
there is a detectable wolf ancestry and how much in
(07:23):
modern dogs. And these are researchers at the American Museum
of National History, New York Smithsonian National Museum of National
History and have found the majority of today's dog have
wolf ancestry genetic They can prove it. Now the fun
part is the levels of wolf ancestry, the ancestral ties
(07:48):
because of DNA to wolves is very low, but is detectable.
Speaker 1 (07:53):
And these ties.
Speaker 2 (07:56):
Have probably impacted how the dog's body size since the
personality traits are there. And the scientists studied twenty six
hundred wolf and dog DNA sets and found that sixty
four percent of modern breed dogs carry wolf ancestry. And
this is due to the genetic cross breeding, because people
crossbred dogs like crazy. And now we have, you know,
(08:20):
these dogs and many different kinds and the highest amount
of wolf ancestry, and no one's going to guess this
happens to be the free roaming village dogs, which I
have no idea what a free roaming village dog is
because I don't have free roaming dogs and I don't
live in a village.
Speaker 1 (08:40):
Audrey Lynn is the lead author of this study and says.
Speaker 2 (08:43):
Prior to the study, the leading science suggested that in
order for dog to be a dog, there can't be
very much wolf DNA left in the dog because it's
all gone. However, in modern dog genomes, wolf is there in.
The question is how much so. Today, dogs as we
(09:04):
know them are the result of evolution, starting with gray
wolves that we know who lived thousands.
Speaker 1 (09:11):
Of years ago.
Speaker 2 (09:13):
People and gray wolves interacted more and more food, you know,
they were coming up. It makes sense, and the wolves
became domesticated and the gene pool starts separating. And this
connection between wolves and dogs is called something introgression. It
(09:34):
occurs when a parent species repeatedly transfers genetic material into
the gene pool of another species and off it splits
and they become different like dogs. Now it's rare, but
animals have done this in order to survive. And here
is the fun part. It's not a question of just
(09:56):
wolves eating. You know, coming up, you have a piece
of chicken or an animal, a piece of game, and
you throw it to the wolf, and then you throw
it closer and closer, and it comes up and realizes
you're a good guy. Over thousands of years, but it
was done in animals to survive. For example, wolves were
(10:16):
brought in or wolves slash dogs high altitude survival. They
are not high altitude, yet they were bred to be
high altitude.
Speaker 1 (10:24):
They became high altitude.
Speaker 2 (10:27):
They added this transfer of high altitude genes if you want,
and as wolves became dogs, and what it was helping
dogs survive. It's a question of survival, not just inner breeding.
And so the researchers looked at multiple breeds and they
(10:48):
started well they actually looked at the United Kennel Clubs
categories and then categories the animals, and this is hilarious,
well not hilarious, but I don't understand it.
Speaker 1 (10:57):
Twelve final groups sled dogs. We all know what the
are about, pariahs.
Speaker 2 (11:03):
I'm assuming they're much like I am on the show Paria.
Speaker 1 (11:08):
Hunting dogs.
Speaker 2 (11:09):
We get that, fighting dogs, Okay, we know about that
sight hounds, which is different than scent hounds.
Speaker 1 (11:20):
Then they're just hounds.
Speaker 2 (11:22):
Then they're hurting dogs, and the toy dogs and guardian
dogs and gun dogs, gun dogs who are some of
them are so good at hunting and shooting that they
go to the Olympics for the dog category. And terriers
and three of the breeds the DNA showed consistent and
(11:47):
more evidence of wolf antistry wolf ancestry.
Speaker 1 (11:52):
Okay, here's three breeds that I'm sure you know.
Speaker 2 (11:56):
The Great Anglo French tricolor hound, the Great ang Goal
or Anglais French tricolor hound. Okay, that's the two, and
I don't know the difference, and the Shiloh Shepherd. These
have the most wolf DNA and I have no idea
(12:18):
what those are about.
Speaker 1 (12:19):
But I just wanted to share with you.
Speaker 2 (12:21):
And then interestingly enough, the team found that wolf ancestry
to a small amount in dogs like chihuahuas. Do Chihuahua's
remind you of wolves? They nip at your ankles, And
there were multiple patterns. For example, large dogs have higher
(12:43):
wolf ancestry in them. We're talking about Arctic sled dogs,
Paria breeds, whatever that is, hunting dogs. And the ones
that have the least are the terriers, the gun dogs,
and the scent hound hogs or no, not hound hogs,
the scent hounds, you know, like the bassett hounds.
Speaker 1 (13:05):
Right with the big ears, and those are great fun.
Speaker 2 (13:08):
And how wolves had actually helped the dogs adapt to
their surroundings. So it's not just interbreeding with people doing
this interbreeding and having different dogs. It is literally adapting
to surroundings. For example, the smell their smell trait. There
are village dogs, they have the strongest ones, rely on
(13:30):
food waste that people threw away, right, and dogs had
to solve all kinds of evolutionary problems that comes with
living with humans, either surviving at a high altitude, searching
for their next meal, protecting the herd. And I've got
two little doxies, as you know. And they are bred
(13:53):
and succeed admirably, admirably at peeing in the house, crapping
in the house, barking incessantly, and uh when someone comes
to the door, nipping at their ankles. I have hugely
successful dogs. Okay, we're done, fair enough, cono dog.
Speaker 1 (14:18):
I love a dog. I don't care if you love them.
Do you have one? There's a lot of around my city.
There's on the street. And then does that mean does
that mean no? Yeh okay? And I know, uh, Amy,
you have a cat, right, I have two cats. I
used to have dogs.
Speaker 2 (14:33):
Ah, yeah, I know, I get that. There's a lot
of I'm such a dog person. I just don't like cats.
I'm just not into cats. They just don't taste this good. Uh.
Speaker 1 (14:44):
And yes, yes, you have dogs? How many dogs? You
have to see me too? Two dogs? What kind do
you have?
Speaker 2 (14:52):
Lab?
Speaker 1 (14:53):
And a husky? Oh?
Speaker 2 (14:55):
Okay, oh husky. I love huskies. They don't even bark,
they howl. Yeah, I love it.
Speaker 1 (15:00):
Yeah. My daughter has a husky and it just howls.
Speaker 2 (15:02):
Oh.
Speaker 1 (15:03):
I love that dog. Okay.
Speaker 2 (15:05):
Doctor Jim Keeney, chief medical Officer for Dignity Saint Mary
Medical Center in Long Beach. Jim is also donating a
flesh eating bacteria just to watch it happen for our
people here at KFI that can tune in on TV.
Speaker 1 (15:22):
Good Morning Jim, Good morning Bill.
Speaker 2 (15:26):
Okay, we've got a couple of things to talk about. Hey,
here's something that is not on our list, and that
is the study that just came out that shows that
turkey that is full of nitrates, processed turkey, nitrates, preservatives,
all kinds of chemicals.
Speaker 1 (15:43):
Are actually better for you than fresh turkey. Is that true?
I don't know anything about that.
Speaker 2 (15:52):
Okay, just how do we do it?
Speaker 3 (15:55):
Sounds like a study you made up?
Speaker 1 (15:57):
Oh really? Okay. The bird flu.
Speaker 2 (16:01):
There's a Washington resident who died of complications from it,
and this strain has never been reported before in humans.
Speaker 1 (16:09):
How scary is that? For real?
Speaker 3 (16:12):
Yeah? So, I mean this is the standard scary of influenza,
which is that you know it has type influenza has
two different proteins on it H and the end. And
so we have H one N one H one N
two in every combination in between all the way and
the bird This bird flu is now H five and five.
(16:33):
So if you know in humans. We have not seen
that in our bodies before. We would not necessarily have
any natural immunity to it, and it could have be
a pretty disastrous flu if it was able to be
transmitted from human to human. Now, this individual had a
flock of birds, domesticated birds in his backyard, some kind.
(16:55):
I don't know whether they were chickens or turkeys or
other kind of birds, but the assumption is that he
caught them from his own birds. This was a bird
to human transition transmission, and so that's less likely to occur,
you know, widespread, and so as long as it's not
human to human, we're okay.
Speaker 1 (17:16):
Still.
Speaker 2 (17:17):
Hey, first of all, the question is are there an
unlimited number of flus out there and most of them
we don't even know they're around because people have not
gotten them or animals have not gotten them. And if
we're talking about a bird to human transfer and then
human to human of this flu of which we've never
(17:39):
heard of before, are we talking about pandemic level problems? Right?
Speaker 3 (17:45):
That's what the surveillance is all about, is that you know,
the flu occurs in nature and animals, and there are
animals that are vectors that can give it to humans,
and in this case, it looks like that's what happened
in animal gave it to a human. Now, animally human
spread is one thing we have really close contact, which
is unusual for us nowadays in modern society. So it's
(18:07):
when it switches to human human transmission that suddenly we
pay attention. There's probably flus out there that we're unaware
of the animals, but when humans get sick, we pretty
frequently will test for it, and then they end up
with these newer flues testing doing genetic testing, which gives
us almost a genetic fingerprint for exactly what it is.
(18:28):
And nowadays it's hard for a new flu to hide
in plain sight anymore.
Speaker 2 (18:34):
Is there a number of flus that we know about
that are running around? Yeah?
Speaker 3 (18:40):
There are, there are. That's what the flu shot is
every year. Right, we look at what the flues are
that are running around in the southern hemisphere and we
predict that those might be the ones in the northern hemisphere,
and we pick each category like the H one, N one,
H two and three, and there's there's a predominant flu
in each of those H and N categories for the
(19:01):
A vaccine, and then there's a B Influenza B that
there's a vaccine for too as well.
Speaker 2 (19:07):
And the question is before we take a break is
and I think we went off on a track where
I misspoke and I did a question that I did wrongly,
and that is do they know that the number of
flu variants out there? And I know they have to guess,
but you know, are there thousands? Are there hundreds variants
(19:30):
that we know about?
Speaker 3 (19:33):
No, No, there's there's a much smaller number of those
couple handfuls of different flu variants. And that's the ones
that okay, we can predict. There's variants of you know,
H two, N three, and then that they predict which
variant of that is most likely to be predominant, and
that way they get the closest match to the immunity.
Speaker 2 (19:52):
Okay, real quickly, before we dive into the factor that
can cause Parkinson's and that is a flu shot which
I get every year. How often are they guess right?
And what does that mean? Guess right? The percentage of efficacy?
Speaker 3 (20:08):
Right, Yeah, that's what I was going to say to me.
It's more important it's how effective it is. And the
average year we're running about fifty percent effective. Like that
you know, people think medications and vaccines and all that
are supposed to be one hundred percent effective and they
never are. So typically the flu is flu vaccine is
fifty percent effective. But if an average year is like
(20:32):
close to ten percent of the population gets the flu,
that would be a big year. But it's close to that.
And we have three hundred million Americans. That's thirty million
people get the flu. If you can cut that in half,
you say fifteen million people getting the flu. So it's
significant and it's you know, from a population health standpoint,
it's worth doing.
Speaker 2 (20:53):
Okay, moving over to what is a warning about an
overlooks factor? Well, and overlook factor they can cause Parkinson's.
Let's talk about that for a moment. That is scary
because Parkinson's scar is a crop out of everybody.
Speaker 3 (21:12):
Yeah. So, I mean, first of all, Parkinson's a movement disorder, right,
So it's an area of the brain called the substantia niagra.
It's in the basal ganglia, which is kind of in
your midbrain, and they put all the important stuff in
the middle of your brain, the furthest from the outside
because it's the most protected. So where you breathe, where
your heart beats and where you move is all in
(21:33):
the center of your brain. And when this goes bad,
basically it makes it difficult to have normal movements. And
we know dopamine is something that stimulates like, you know,
motivation and positiveness. Right, it's a We know that dopamine
is released when you're scrolling the internet and things like that,
when you're doing things you enjoy. But it also is
(21:56):
kind of motor oil for movements, right, So these nerves
are dopamine energic nerves that smooth out your movements and
create normal movements. So when people get Parkinson's, that's all
messed up. Now bear with me on this one. It starts,
we believe it may start in your gut because your
gut has like many brain cells in it. They really
(22:18):
extend all the way up to the brain along the
vagus nerve. And in those cells we first start seeing
this protein that was recently discovered, the alpha sin protein.
And when that thing is misshapen and misfolded, we notice
that it doesn't work right. It comes up the system
and it can travel up those gut nerves into the brain. Well,
(22:39):
now it comes microplastics and micro and nanoplastics. When we
dissect human brains, we find that in their brains, and
we find it in people with Parkinson's. There's no evidence
yet that it causes Parkinson's, but a study just came out.
That's what we're talking about really here. Study and mouse
and my who are prone to getting Parkinson's disease. When
(23:02):
they feed them microplastics, the Parkinson's gets much worse. And
they believe it's along that whole gut liver brain kind
of pathway that we are aware of now that connects
your gut to your brain.
Speaker 2 (23:19):
Wow, Okay, now that is I guess that's important news.
Although the thought of getting Parkinson's. Of course, my mother
had Parkinson's, and it is not pleasant to be around
the people who do. It's even more unpleasant to actually
have it. Jim is always thank you. We'll talk next
week also tomorrow. Enjoy your Thanksgiving. I hope you eat well.
(23:41):
And by the way, for everybody out there on behalf
of Jim and I. If you get food poisoning, that's
simply the cost of doing business. And Neil is here
tomorrow morning on our show. It'll be his show tomorrow Thanksgiving,
which he does every Thanksgiving from six to nine.
Speaker 1 (23:58):
I think wake Up Call is still happen, uh, is
it not? Okay? Amy and Will Will's not.
Speaker 2 (24:04):
Even so it'll be Amy with wake up Call in
the morning, and we're gonna all eat a lot of turkey,
right absolutely, I'm going I'm going to a deli. I'm
going to a deli. It's just easier.
Speaker 1 (24:15):
Are you gonna have turkey though at the deli?
Speaker 2 (24:17):
Are you? I don't know, I don't I don't know.
I don't think I may have turkey pastrami. It does, okay?
All kinds of good advice with Neil tomorrow for Thanksgiving
and nice gobbled. You've been listening to The Bill Handle
Show Catch My Show Monday through Friday six am to
(24:39):
nine am, and anytime on demand on the iHeartRadio app
You're listening to Bill Handle on demand from kf I
am six forty.
Speaker 2 (00:07):
I am six forty Bill Handle here on a Wednesday morning, Hopday,
November twenty sixth, tomorrow being Thanksgiving. Neil Savedra is silly
in for me, as he does every Thanksgiving, and he
will be there tomorrow and Friday, and then we go
back to regularly scheduled broadcast. And I don't know if
(00:31):
I'm going to do it on Saturday, handle on.
Speaker 1 (00:34):
The law, but.
Speaker 2 (00:37):
If not, what we what we'll do is I'll run
a show and I'll pretend that I'm there even though
I'm not there, to fool you guys into thinking I
am there. See. One of the things I do on
Tuesdays and Thursdays is I take these phone calls, as
you know, off the air for future broadcast. This is
what it's about. So Saturday, you have to guess Bill
(01:00):
there or not.
Speaker 1 (01:01):
Oh, that's a contest.
Speaker 2 (01:02):
We should give something away for people that guess correctly,
So flip a coin. But don't worry about it. If
I'm not there, You'll think I'm there. So everything is cool. Damn,
do I do a good job on this broadcast, don't
I damn straight, Okay, I happen to be a sort
of a fanatic about real estate prices.
Speaker 1 (01:23):
I just it's the thing for me.
Speaker 2 (01:25):
I just happened to talk about and enjoy, literally enjoy,
and in my head and with others get into prices.
And since I just bought my home, we talked prices,
since I sold the Persian Palace, I'm particularly interested in
home prices these last days. So let's talk about you.
(01:45):
If you're serious about selling your home, you probably have
to drop the price. Overpriced houses are languishing on the market.
Buyers are continued to be deterred by elevated mortgage rates.
Speaker 1 (01:58):
There's no longer three percent money.
Speaker 2 (02:01):
Economic uncertainty during COVID and everybody was staying at home,
and all of a sudden.
Speaker 1 (02:06):
Houses go up in value right after that.
Speaker 2 (02:11):
Sellers actually optimistically priced their homes based on sales from
the twenty from the twenty twenties, right from five years ago,
when there was three percent money, when there were plenty
of houses available and people were snamping them up. Jessica Lotts,
who's deputy chief Economists at the National Association of Realtors,
(02:33):
who's really on top of that, tells owners. If you
are going to sell, calibrate your asking price by looking
at what comparable houses are in the neighborhood that sold
for the last month or so. Do not go back
five years. That ain't happening. What you want to do
(02:53):
is what happened the last couple of months. Twenty percent
of listings in October had a price cut, according to
realtor dot com. That's a lot of homes that are
price cut because we're used to having homes that are
just snapped up.
Speaker 1 (03:09):
Well that's not the case anymore.
Speaker 2 (03:11):
And by the way, the twenty percent is twice as
high as when the price is soared during the pandemic.
And what happens if you set the price too high, Well,
it doesn't sell, It drags on and you have to
lower the price. After a period of several months, you
realize I can't get the price, so I now have
(03:32):
to lower it. Listings that sold after the price reduction
spend five times as many days on the market as
the average home that was listed correctly.
Speaker 1 (03:43):
Now keep in mind, I mean what does that mean.
Speaker 2 (03:45):
Okay, you have listed your house and it's too expensive,
and then you reduce the price. Well, even after the reduction,
It takes five times longer to sell your house. If
the home is priced directly, they also get one hundred
percent of their asking price almost immediately. When I bought
(04:05):
my house here in Orange County, I paid market for
the price I paid what was basically listed. I got
a little bit of a discount, but not much. And
that's if it was priced correctly, and a house across
the street sold and a house down the street sold
very quickly.
Speaker 1 (04:26):
They were priced correctly in my neighborhood.
Speaker 2 (04:29):
If the listing has been around on the market for
a month or more, what happens is home buyers are
now talking about negotiating a discount after three months if
your house is on the market. Usually prices dropped by
five percent after a year, and there are plenty of
homes that sit there for a year when the price
way too high. Then that reduces more than twelve percent.
(04:53):
And keeping on to a house that is too high
priced for period of many months or a year, imagine
what it costs you. If you already moved, you're screwed.
You have an empty house and is costing you a fortune.
But even you have to stay well if you're selling
it based on if you're buying it based on another house,
or selling it based on a property that you've bought
(05:14):
or intend on buying, you're holding on You can't do that.
So today it's buyers who have time, they have leverage,
and they're making offers under.
Speaker 1 (05:25):
The listing price. Remember the stories.
Speaker 2 (05:27):
I mean, people were buying houses for a period of
time site unseen because there was such a ridiculous demand
for housing, and they were offering prices that were way higher,
I mean over market. So a house to be listed
at seven hundred thousand dollars, let's say, quite often it
(05:47):
went for eight hundred eight point fifty.
Speaker 1 (05:50):
That's what it used to be.
Speaker 2 (05:52):
Not that way any longer. You have to be realistic
about it when listing a price. And just to tell
you how crazy I am about looking at housing prices,
Lindsay spent a couple of days in Las Vegas and
she brought home usually you know yet little knickknacks magnet
for the mirror, that sort of thing. She brought home
(06:14):
a booklet of homes that were listed. You've seen those
home magazines, and I go through it. Okay, this one,
oh my god, this isn't worth two million dollars. Look
at this, this is what they offer, this is what
they don't.
Speaker 1 (06:29):
So having been that way, now an easy way.
Speaker 2 (06:32):
Of course of selling your home, and I do commercials
as you know, for direct buyers dot com. None of
that happens. I mean that just disappears instantly. But there
are many ways to sell your house, as you know.
Speaker 1 (06:46):
There you go.
Speaker 2 (06:47):
And one fun story about dogs, modern dogs and how
they have well connected to wolves.
Speaker 1 (06:56):
And we know that dogs.
Speaker 2 (06:59):
Came from wolves, I mean that's sort of a given.
And then and interbreeding of wolves and dogs and over
the thousands and thousands of years, I mean going back
maybe thirty thousand years, you have the modern dog now.
But there is now a science science has proven that
there is a detectable wolf ancestry and how much in
(07:23):
modern dogs. And these are researchers at the American Museum
of National History, New York Smithsonian National Museum of National
History and have found the majority of today's dog have
wolf ancestry genetic They can prove it. Now the fun
part is the levels of wolf ancestry, the ancestral ties
(07:48):
because of DNA to wolves is very low, but is detectable.
Speaker 1 (07:53):
And these ties.
Speaker 2 (07:56):
Have probably impacted how the dog's body size since the
personality traits are there. And the scientists studied twenty six
hundred wolf and dog DNA sets and found that sixty
four percent of modern breed dogs carry wolf ancestry. And
this is due to the genetic cross breeding, because people
crossbred dogs like crazy. And now we have, you know,
(08:20):
these dogs and many different kinds and the highest amount
of wolf ancestry, and no one's going to guess this
happens to be the free roaming village dogs, which I
have no idea what a free roaming village dog is
because I don't have free roaming dogs and I don't
live in a village.
Speaker 1 (08:40):
Audrey Lynn is the lead author of this study and says.
Speaker 2 (08:43):
Prior to the study, the leading science suggested that in
order for dog to be a dog, there can't be
very much wolf DNA left in the dog because it's
all gone. However, in modern dog genomes, wolf is there in.
The question is how much so. Today, dogs as we
(09:04):
know them are the result of evolution, starting with gray
wolves that we know who lived thousands.
Speaker 1 (09:11):
Of years ago.
Speaker 2 (09:13):
People and gray wolves interacted more and more food, you know,
they were coming up. It makes sense, and the wolves
became domesticated and the gene pool starts separating. And this
connection between wolves and dogs is called something introgression. It
(09:34):
occurs when a parent species repeatedly transfers genetic material into
the gene pool of another species and off it splits
and they become different like dogs. Now it's rare, but
animals have done this in order to survive. And here
is the fun part. It's not a question of just
(09:56):
wolves eating. You know, coming up, you have a piece
of chicken or an animal, a piece of game, and
you throw it to the wolf, and then you throw
it closer and closer, and it comes up and realizes
you're a good guy. Over thousands of years, but it
was done in animals to survive. For example, wolves were
(10:16):
brought in or wolves slash dogs high altitude survival. They
are not high altitude, yet they were bred to be
high altitude.
Speaker 1 (10:24):
They became high altitude.
Speaker 2 (10:27):
They added this transfer of high altitude genes if you want,
and as wolves became dogs, and what it was helping
dogs survive. It's a question of survival, not just inner breeding.
And so the researchers looked at multiple breeds and they
(10:48):
started well they actually looked at the United Kennel Clubs
categories and then categories the animals, and this is hilarious,
well not hilarious, but I don't understand it.
Speaker 1 (10:57):
Twelve final groups sled dogs. We all know what the
are about, pariahs.
Speaker 2 (11:03):
I'm assuming they're much like I am on the show Paria.
Speaker 1 (11:08):
Hunting dogs.
Speaker 2 (11:09):
We get that, fighting dogs, Okay, we know about that
sight hounds, which is different than scent hounds.
Speaker 1 (11:20):
Then they're just hounds.
Speaker 2 (11:22):
Then they're hurting dogs, and the toy dogs and guardian
dogs and gun dogs, gun dogs who are some of
them are so good at hunting and shooting that they
go to the Olympics for the dog category. And terriers
and three of the breeds the DNA showed consistent and
(11:47):
more evidence of wolf antistry wolf ancestry.
Speaker 1 (11:52):
Okay, here's three breeds that I'm sure you know.
Speaker 2 (11:56):
The Great Anglo French tricolor hound, the Great ang Goal
or Anglais French tricolor hound. Okay, that's the two, and
I don't know the difference, and the Shiloh Shepherd. These
have the most wolf DNA and I have no idea
(12:18):
what those are about.
Speaker 1 (12:19):
But I just wanted to share with you.
Speaker 2 (12:21):
And then interestingly enough, the team found that wolf ancestry
to a small amount in dogs like chihuahuas. Do Chihuahua's
remind you of wolves? They nip at your ankles, And
there were multiple patterns. For example, large dogs have higher
(12:43):
wolf ancestry in them. We're talking about Arctic sled dogs,
Paria breeds, whatever that is, hunting dogs. And the ones
that have the least are the terriers, the gun dogs,
and the scent hound hogs or no, not hound hogs,
the scent hounds, you know, like the bassett hounds.
Speaker 1 (13:05):
Right with the big ears, and those are great fun.
Speaker 2 (13:08):
And how wolves had actually helped the dogs adapt to
their surroundings. So it's not just interbreeding with people doing
this interbreeding and having different dogs. It is literally adapting
to surroundings. For example, the smell their smell trait. There
are village dogs, they have the strongest ones, rely on
(13:30):
food waste that people threw away, right, and dogs had
to solve all kinds of evolutionary problems that comes with
living with humans, either surviving at a high altitude, searching
for their next meal, protecting the herd. And I've got
two little doxies, as you know. And they are bred
(13:53):
and succeed admirably, admirably at peeing in the house, crapping
in the house, barking incessantly, and uh when someone comes
to the door, nipping at their ankles. I have hugely
successful dogs. Okay, we're done, fair enough, cono dog.
Speaker 1 (14:18):
I love a dog. I don't care if you love them.
Do you have one? There's a lot of around my city.
There's on the street. And then does that mean does
that mean no? Yeh okay? And I know, uh, Amy,
you have a cat, right, I have two cats. I
used to have dogs.
Speaker 2 (14:33):
Ah, yeah, I know, I get that. There's a lot
of I'm such a dog person. I just don't like cats.
I'm just not into cats. They just don't taste this good. Uh.
Speaker 1 (14:44):
And yes, yes, you have dogs? How many dogs? You
have to see me too? Two dogs? What kind do
you have?
Speaker 2 (14:52):
Lab?
Speaker 1 (14:53):
And a husky? Oh?
Speaker 2 (14:55):
Okay, oh husky. I love huskies. They don't even bark,
they howl. Yeah, I love it.
Speaker 1 (15:00):
Yeah. My daughter has a husky and it just howls.
Speaker 2 (15:02):
Oh.
Speaker 1 (15:03):
I love that dog. Okay.
Speaker 2 (15:05):
Doctor Jim Keeney, chief medical Officer for Dignity Saint Mary
Medical Center in Long Beach. Jim is also donating a
flesh eating bacteria just to watch it happen for our
people here at KFI that can tune in on TV.
Speaker 1 (15:22):
Good Morning Jim, Good morning Bill.
Speaker 2 (15:26):
Okay, we've got a couple of things to talk about. Hey,
here's something that is not on our list, and that
is the study that just came out that shows that
turkey that is full of nitrates, processed turkey, nitrates, preservatives,
all kinds of chemicals.
Speaker 1 (15:43):
Are actually better for you than fresh turkey. Is that true?
I don't know anything about that.
Speaker 2 (15:52):
Okay, just how do we do it?
Speaker 3 (15:55):
Sounds like a study you made up?
Speaker 1 (15:57):
Oh really? Okay. The bird flu.
Speaker 2 (16:01):
There's a Washington resident who died of complications from it,
and this strain has never been reported before in humans.
Speaker 1 (16:09):
How scary is that? For real?
Speaker 3 (16:12):
Yeah? So, I mean this is the standard scary of influenza,
which is that you know it has type influenza has
two different proteins on it H and the end. And
so we have H one N one H one N
two in every combination in between all the way and
the bird This bird flu is now H five and five.
(16:33):
So if you know in humans. We have not seen
that in our bodies before. We would not necessarily have
any natural immunity to it, and it could have be
a pretty disastrous flu if it was able to be
transmitted from human to human. Now, this individual had a
flock of birds, domesticated birds in his backyard, some kind.
(16:55):
I don't know whether they were chickens or turkeys or
other kind of birds, but the assumption is that he
caught them from his own birds. This was a bird
to human transition transmission, and so that's less likely to occur,
you know, widespread, and so as long as it's not
human to human, we're okay.
Speaker 1 (17:16):
Still.
Speaker 2 (17:17):
Hey, first of all, the question is are there an
unlimited number of flus out there and most of them
we don't even know they're around because people have not
gotten them or animals have not gotten them. And if
we're talking about a bird to human transfer and then
human to human of this flu of which we've never
(17:39):
heard of before, are we talking about pandemic level problems? Right?
Speaker 3 (17:45):
That's what the surveillance is all about, is that you know,
the flu occurs in nature and animals, and there are
animals that are vectors that can give it to humans,
and in this case, it looks like that's what happened
in animal gave it to a human. Now, animally human
spread is one thing we have really close contact, which
is unusual for us nowadays in modern society. So it's
(18:07):
when it switches to human human transmission that suddenly we
pay attention. There's probably flus out there that we're unaware
of the animals, but when humans get sick, we pretty
frequently will test for it, and then they end up
with these newer flues testing doing genetic testing, which gives
us almost a genetic fingerprint for exactly what it is.
(18:28):
And nowadays it's hard for a new flu to hide
in plain sight anymore.
Speaker 2 (18:34):
Is there a number of flus that we know about
that are running around? Yeah?
Speaker 3 (18:40):
There are, there are. That's what the flu shot is
every year. Right, we look at what the flues are
that are running around in the southern hemisphere and we
predict that those might be the ones in the northern hemisphere,
and we pick each category like the H one, N one,
H two and three, and there's there's a predominant flu
in each of those H and N categories for the
(19:01):
A vaccine, and then there's a B Influenza B that
there's a vaccine for too as well.
Speaker 2 (19:07):
And the question is before we take a break is
and I think we went off on a track where
I misspoke and I did a question that I did wrongly,
and that is do they know that the number of
flu variants out there? And I know they have to guess,
but you know, are there thousands? Are there hundreds variants
(19:30):
that we know about?
Speaker 3 (19:33):
No, No, there's there's a much smaller number of those
couple handfuls of different flu variants. And that's the ones
that okay, we can predict. There's variants of you know,
H two, N three, and then that they predict which
variant of that is most likely to be predominant, and
that way they get the closest match to the immunity.
Speaker 2 (19:52):
Okay, real quickly, before we dive into the factor that
can cause Parkinson's and that is a flu shot which
I get every year. How often are they guess right?
And what does that mean? Guess right? The percentage of efficacy?
Speaker 3 (20:08):
Right, Yeah, that's what I was going to say to me.
It's more important it's how effective it is. And the
average year we're running about fifty percent effective. Like that
you know, people think medications and vaccines and all that
are supposed to be one hundred percent effective and they
never are. So typically the flu is flu vaccine is
fifty percent effective. But if an average year is like
(20:32):
close to ten percent of the population gets the flu,
that would be a big year. But it's close to that.
And we have three hundred million Americans. That's thirty million
people get the flu. If you can cut that in half,
you say fifteen million people getting the flu. So it's
significant and it's you know, from a population health standpoint,
it's worth doing.
Speaker 2 (20:53):
Okay, moving over to what is a warning about an
overlooks factor? Well, and overlook factor they can cause Parkinson's.
Let's talk about that for a moment. That is scary
because Parkinson's scar is a crop out of everybody.
Speaker 3 (21:12):
Yeah. So, I mean, first of all, Parkinson's a movement disorder, right,
So it's an area of the brain called the substantia niagra.
It's in the basal ganglia, which is kind of in
your midbrain, and they put all the important stuff in
the middle of your brain, the furthest from the outside
because it's the most protected. So where you breathe, where
your heart beats and where you move is all in
(21:33):
the center of your brain. And when this goes bad,
basically it makes it difficult to have normal movements. And
we know dopamine is something that stimulates like, you know,
motivation and positiveness. Right, it's a We know that dopamine
is released when you're scrolling the internet and things like that,
when you're doing things you enjoy. But it also is
(21:56):
kind of motor oil for movements, right, So these nerves
are dopamine energic nerves that smooth out your movements and
create normal movements. So when people get Parkinson's, that's all
messed up. Now bear with me on this one. It starts,
we believe it may start in your gut because your
gut has like many brain cells in it. They really
(22:18):
extend all the way up to the brain along the
vagus nerve. And in those cells we first start seeing
this protein that was recently discovered, the alpha sin protein.
And when that thing is misshapen and misfolded, we notice
that it doesn't work right. It comes up the system
and it can travel up those gut nerves into the brain. Well,
(22:39):
now it comes microplastics and micro and nanoplastics. When we
dissect human brains, we find that in their brains, and
we find it in people with Parkinson's. There's no evidence
yet that it causes Parkinson's, but a study just came out.
That's what we're talking about really here. Study and mouse
and my who are prone to getting Parkinson's disease. When
(23:02):
they feed them microplastics, the Parkinson's gets much worse. And
they believe it's along that whole gut liver brain kind
of pathway that we are aware of now that connects
your gut to your brain.
Speaker 2 (23:19):
Wow, Okay, now that is I guess that's important news.
Although the thought of getting Parkinson's. Of course, my mother
had Parkinson's, and it is not pleasant to be around
the people who do. It's even more unpleasant to actually
have it. Jim is always thank you. We'll talk next
week also tomorrow. Enjoy your Thanksgiving. I hope you eat well.
(23:41):
And by the way, for everybody out there on behalf
of Jim and I. If you get food poisoning, that's
simply the cost of doing business. And Neil is here
tomorrow morning on our show. It'll be his show tomorrow Thanksgiving,
which he does every Thanksgiving from six to nine.
Speaker 1 (23:58):
I think wake Up Call is still happen, uh, is
it not? Okay? Amy and Will Will's not.
Speaker 2 (24:04):
Even so it'll be Amy with wake up Call in
the morning, and we're gonna all eat a lot of turkey,
right absolutely, I'm going I'm going to a deli. I'm
going to a deli. It's just easier.
Speaker 1 (24:15):
Are you gonna have turkey though at the deli?
Speaker 2 (24:17):
Are you? I don't know, I don't I don't know.
I don't think I may have turkey pastrami. It does, okay?
All kinds of good advice with Neil tomorrow for Thanksgiving
and nice gobbled. You've been listening to The Bill Handle
Show Catch My Show Monday through Friday six am to
(24:39):
nine am, and anytime on demand on the iHeartRadio app
The Bill Handel Show News
Popular Podcasts
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Las Culturistas with Matt Rogers and Bowen Yang
Ding dong! Join your culture consultants, Matt Rogers and Bowen Yang, on an unforgettable journey into the beating heart of CULTURE. Alongside sizzling special guests, they GET INTO the hottest pop-culture moments of the day and the formative cultural experiences that turned them into Culturistas. Produced by the Big Money Players Network and iHeartRadio.
Crime Junkie
Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.