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Dr. Mikael Palner is an associate professor in the Department of Clinical Research at the University of Southern Denmark, studying the biological correlates of maladaptive neuropsychiatric diseases—such as anxiety, obsessive-compulsive disorder, post-traumatic stress syndrome.
He joins us to discuss his research on the positive effects of psilocybin microdosing on stress resiliency, compulsions, and neuroplasticity; as well as what microdosing IS NOT good for, and some important cautions to consider with respect to potential harms of microdosing.
We also discuss why studies in rats show clear biological effects of microdosing on behaviour, but human studies seem to suggest placebo; a neural level definition of psychedelic microdosing; why microdosing research is being polluted by a lack of specificity; the value of the “psychedelic” effect of psychedelics in their use as a medicine; and why what rats need higher doses of psychedelics than human by weight.
Enjoy!
🌀 Website and Episode Show Notes
FULL TOPICS BREAKDOWN BELOW
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Episode Breakdown
- (00:00) Opening
- (05:02) Interview begins
- (05:08) Psychedelic microdosing (vs low doses)
- (06:44) The scientific study of psychedelic microdosing
- (08:43) A neural level definition of psychedelic microdosing
- (10:36) An explanation of receptor site binder occupan
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