October 28, 2024 • 35 mins
We’re thrilled to have Anthony Castor on the show. We'll be discussing a groundbreaking compound, SLU-PP 332, which uniquely targets estrogen-related receptors to enhance energy metabolism, aid fat loss, and improve mitochondrial health. Anthony will explain the fascinating concept of mitochondrial biogenesis and how SLU-PP 332 mimics the benefits of exercise by activating nuclear receptors and promoting metabolic efficiency.
Hear about his personal experience with this potent compound, the protocols he followed, and the impressive outcomes he observed in energy, mental clarity, and health biomarkers. We’ll also delve into the science behind cellular mechanisms, such as the activation of AMPK and its impact on energy states, fat burning, and muscle protein synthesis. Plus, we’ll highlight the importance of foundational health practices and the latest on our collaboration in developing research compounds to enhance health and performance.
Stay tuned as we explore the exciting potentials of SLU-PP 332 and invite you to join our community for more insights and support. Let's get started on this journey towards resilience and optimal health!
This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by
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Contents:
00:00 Mitochondria: The body's engine, crucial for energy.
05:46 Cell energy regulation during exercise via AMPK.
9:55 Hormonal optimization
12:49 mTOR activation
15:43 Calcium and antioxidants interact during exercise.
23:49 SLU PP activates energy production
28:34 Intake protocol.
33:34 Prioritize health fundamentals before exploring peptides.
34:57 Game-changing community for learning and support.
Join my FREE Education Platform & Community https://chrisduffin.com/start-here
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Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
(00:00):
Welcome to the architect of Resilience podcast, where
we explore the secrets of overcoming life's challenges and
unlocking unstoppable strength through deep personal
conversations and expert insights. Chris Duffin and
Anthony Kastor with you today. We have
something very exciting to dive into that probably
(00:22):
hardly anybody's heard about, because, one, it's just not available, but actually
it is. Uh, so we'll talk about that later. Uh, we just
had a nice warm up on glucose shuttling on another episode
that we randomly shot off the. Off our hip. Uh,
the. Today, I'm probably going to be doing a little bit more interview
fashion, but we're going to be covering a very unique compound.
(00:45):
It's a small molecule that is,
it's an exercise mimetic, right. And it does this by
targeting estrogen related receptors. Errs.
Uh, it's an err panel pan agonist. And that is a group
of nuclear receptors involved in regulating energy metabolism.
Mitochondrial biogenesis. Actually, I just talked about that with
(01:08):
the four hil, uh, uh, compound because there
was kind of some overlay and discussion. Uh, and oxidative,
uh, metabolism, long and short
like this is an incredible product for stripping
fat off your body, preserving muscle, and
improving metabolic health. So,
(01:31):
yeah. Do you want to give us a rundown on the key
mechanisms? Oh, I guess I haven't said what it is. What are we talking about
today, Anthony? Yeah, I'm super excited about today's
discussion. As Chris said, like, some people may have heard of it,
but not really accessible until basically now
we're going to be talking about SLU pp 332.
(01:54):
And that's not a combination to a lock or a secret code name.
It's actually secret code made to some radical fat loss
and metabolic health, but. Yeah. Yep,
exactly. And you have to have a secret knock to order
it. But other than that,
(02:14):
I think maybe before we talk about it, just kind of a quick refresher on
the mitochondria is going to make this make a lot of sense. And when we
think about our mitochondria and then being so, so crucial,
it's kind of like our body's this high performance car, like a Tesla
or Bugatti or something. And
your choice on that shoot, it could be a Corvette.
(02:37):
Mitochondria are going to be the engine. And the
better the engine is, the faster and more efficiently your car runs.
And before you ignore your engine maintenance, like the
mitochondrial health, you're going to end up running on fumes. And
no matter how shiny the exterior looks, when it comes to performance,
whether it's crushing it in the gym. Or if we're talking about, like,
(02:59):
recovering after a workout or even just living longer. Your mitochondria
are basically the unsung heroes of this. And
the way that slupp 332 is going to fit into this
is a couple different things. It's an exercise memetic,
which is fascinating in and of itself. We'll talk about that a little
bit, and basically what that means.
(03:22):
Exercise memetics can
essentially mimic some of the effects of exercise without
having to do the actual workout. So, kind of imagine, like,
you're getting some of the benefits of a jog while you're
binge watching Netflix. I know for a lot of people, that probably sounds
pretty, pretty appealing, and at the same time, it's like, well, how can I
(03:45):
do that? And definitely, it's doing
that by causing an
increase in the mitochondrial function and enhancing energy
expenditure. So just like going for a
jog would, right. And in essence, doing
a set of bench press is going to do the same thing, but it's
(04:07):
clearly not going to do. The effect of the other aspects
of doing a bench press workout are going to be. So when
we say s exercise mimedic, we're talking about the enhanced energy
expenditure of a workout. Yeah. And it
definitely doesn't take the place of working out. It's just something that if you're
already doing the right things in the gym, it's going to
(04:29):
improve your. Your results and all
that good stuff. As you mentioned, Chris, it's going to
boost the mitochondrial function. And I also helps with
mitochondrial biogenesis. What that means when we think about
biogenesis, you're creating more mitochondria.
And when we do this, since each of those, as we recall, are
(04:52):
essentially like the horsepower of the engine of our car, now we've
got two engines in that Bugatti instead of
one. So it's going to be even faster and perform even
better. And scientists are getting really excited
about this one. It's going to have application
for metabolic disorders, muscle
(05:14):
atrophy, cognitive decline. It's
almost like they found a way to biohack ourselves. I hate to use that word,
but we're really on the cusp of something great.
Every time I hear somebody say biohack, I think of Dave Asprey without his
shirt off in his office, crunching. So his abs are flexed,
but he's got this weird look like this. You know what I'm talking about?
(05:43):
Sorry. No, I know
exactly what you're talking about. And I get the same visual. I think that's probably
why I don't like the word,
I think, to maybe help people understand, like when we talk about
exercise, memetic, sort of what's happening on a cellular level, if we kind
(06:04):
of break it down, might
put a little bit more context to it. So
the first thing is AMPK,
and that's going to be like the Amp activated protein
kinase. And the way to think about that is
Ampk is like the cell's energy gauge
(06:25):
and it's going to be activated if the cell
senses low energy. So like
higher levels of ampk compared to ATP,
adenosine monophosphate one compared to adenosine
triphosphate three. And that's something that
happens, like during exercise because we're using up that
(06:47):
ATP. And when you work out, energy
stores are going to be depleted and AMPK gets
switched on and tells your cells to generate more ATP by burning
fat. This is going to also help with
increasing glucose uptake, enhancing mitochondrial
function. And it's almost like putting your cells in this energy
(07:08):
efficient mode. And the way that SLU PP
332 mimics it is it
directly activates this amPk, even without
exercise, and it makes the cell think that it's on this low
energy. So this is going to cause the cell to
react as if it's in a state of this,
(07:29):
like, whoa, I'm exercising, you know, I don't have enough energy here
and it's going to improve those metabolic processes and energy
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(08:15):
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that, we had another discussion where we're talking about that and that
relation to, to mtor as well.
Is there some timing that we need to think about
with the use of this for impacting, uh,
(08:37):
uh, mtor and muscle protein synthesis? Because
obviously the energy sensing. So sensing this low energy
levels is going to help improve the mitochondrial
function using inner, you know, using those resources. So it's going to help
with body composition, right. We're going to get leaner, we're going to retain
muscle mass, but at the same time, if.
(08:59):
If we have mtor shutdown, we're not going to be able to add
muscle mass quite as, uh, effectively, uh, you know,
because muscle protein synthesis requires
massive amounts of energy. And so
when we. When the cell sense low energy like that processes
is essentially kind of shuttled.
(09:21):
Yeah, no, that's a really good point. And the research is
pretty new on this. Most of what you're going to find
is going to be n of one, where people are
reporting their experience with it, and we'll get into some of that
or a lot of animal data.
(09:41):
Personally, my thoughts are it would be something I'd use in the morning
and then prior to a workout, probably about an hour before,
some other things it does. And this will kind of explain my timing behind
it. Well, first, I just. I would put the caveat that
anybody using this is probably doing some sort of hormonal
(10:04):
optimization as a whole anyway, which then would kind of counter
those effects as well. Right. If you're doing some things to,
you know, stimulate growth hormone relief, release or maintain
estrogen levels or some sort of, you know, hormonal
enhancement, it became pretty irrelevant. Just
like, you know, in prior discussion, we talked about, you know, bodybuilders,
(10:26):
professional bodybuilders using metformin. We don't
seem to be lacking any sort of muscle mass on an IFBB pro
using metformin, although at times they still try to,
you know, you know, put that at certain times as it
relates to, um, to training, but others
probably don't, you know, because, again, I having poor
(10:49):
energy metabolism. So a bodybuilder may be doing that because they
have so much androgens in their system
that they've got a level of insulin
resistance developing. And so they may be taking
the metformin to counter that or to help with the
carb displacement, but similar effects with that as it
(11:12):
relates to energy sensing
and the ampk signaling side
of that, some similar thought processes. So just context, right?
Just going context doesn't mean,
but something to be aware of. Yeah,
(11:33):
one of the things, and this will kind of tie into the mtor that's
really cool about the SLU. Pp 332
is it also activates PGC one
alpha. And what that is, it's this master regulator of
mitochondrial biogenesis. And it
kind of turns the dial up when we need to produce more mitochondria
(11:55):
and especially like, during exercise or endurance, endurance training
and with that being kind of a regulator.
And then the other thing, it does, too, it
activates sirtuitin one protein.
And when we exercise and, like,
(12:15):
nad levels increase, this also activates
sirtuitin one. And those are, again, things that are going to help
modulate that mitochondrial function, reduce oxidative stress,
and promote the cellular repair. What's unique about
it, though, with regards to the mtoR. So that's
almost going to bypass a lot of what I'm talking about, because it's going to
(12:38):
create some of those same effects
again, like a hormonal would with preserving or growing muscle
tissue, especially mitochondrial biogenesis.
Yeah. When we think about, like, mtor being
kind of the pathway that regulates the cell growth, protein synthesis, muscle building,
all that good stuff. And then, of course, with
(13:00):
exercise, you know, we're activating that mtor pathway, and
the slupp 332 actually mimics
it. And the way that it does this is kind of unique.
It does this through endurance based pathways like the
AMPK and PGC One Alpha.
And it's kind of an indirect effect on energy balance,
(13:22):
which interacts with the mTOR and
promotes better recovery and health, kind of to untangle that,
because I know that's kind of a complicated explanation
if you think about an endurance runner. And obviously, you know, they're
not massive muscle or anything, but
by running, they're going to build muscle. So. And that
(13:44):
comes through, like, an mtor activation, even though they're primarily
ampk. So when we look at how
slupp 332 is working indirectly, you're getting
kind of that same mtor stimulation
that you'd see in an endurance athlete. And I don't
want people to read too much into that, like, oh, man, it's going to build
(14:05):
slow twitch fibers or whatever. No, it's just there's kind
of more than. More than one way to get to the same
end. So by taking this indirect route to
stimulate the mtor, you're kind of getting the best of both worlds. You're getting
the improved energy metabolism
and activation of the PGC one output, which is going to kind of
(14:27):
regulate everything. And you're getting the
mtor signaling as well. Wow, that's pretty wild. That makes
that just substantially different than anything else that we've
talked about in these classes. Yeah, that's. Yeah,
that's amazing. Truly unique. Yeah. The other thing that it
does, it's kind of interesting, is, like, with the
(14:50):
calcium signaling. So calcium ions are going to act like
signaling molecules in a lot of cellular processes. Like, when we think about
muscle contraction or mitochondrial function. And
during exercise, these calcium levels kind of fluctuate,
and this signals the mitochondria to increase energy
production. So it's meeting that higher demand as it's sensing, like,
(15:12):
these fluctuations in calcium.
What slupp 332 does is
it can affect the calcium signaling pathway,
and it's kind of cool. It tricks these cells into thinking
they're in an exercise state, and then this is going to lead to
enhanced mitochondrial activity and energy output.
(15:35):
So, essentially to kind of unpack that when
we're thinking about every time we contract our
muscle. And I just kind of imagine, like, this tidal wave of calcium going up
and down, and our body trying to make heads or sense of that, or heads
or tails of that and draw some sense from it. The
SLU essentially is kind of telling the body what's happening. Like, all right,
(15:57):
you know, we need a little bit more energy. Calcium is doing this. And
so just kind of another way it's supporting that plays into that
exercise memetic effect that we're talking about.
Then the final thing that's super important to mention
is its effect on reactive oxygen species and the antioxidant
process. So we know, like, when we exercise, we want to have a certain amount
(16:20):
of oxidative stress. And Chris and
I just talked about it and not too long ago, and he
pointed out that, and I agree 100%, that if you
put out the flame, the oxidation
too soon after the workout, you don't stimulate that inflammation. Essentially,
you're just putting a wet blanket over your gains. So we want to have those,
(16:43):
but the key is we want to be able to kind of switch that off
when we need to. And these reactive
oxygen species are basically byproducts of mitochondrial activity,
and they can cause oxidative damage if they're left
unchecked. So during your workout, your
cells basically are going to generate more of these, and
(17:05):
it's going to allow them to become more resilient.
They start producing antioxidants like
glutathione. And that kind of improves the cellular
process. So what the SLU does is it
increases the mitochondrial activity and energy production,
and it increases reactive oxygen species
(17:27):
production in a controlled way. And that's the key in a controlled
way, and that stimulates the cell's antioxidant
defense. So essentially, it's not letting too much out that we're
getting those reactive oxygen species, but it's letting enough that we're
maximizing or that we can kind of calibrate
our glutathione production. So we're putting out just enough of
(17:48):
that fire, but still getting the signal to
adapt and make progress.
And then the other mechanism of action,
and this is one of my favorite areas to kind of
look into uncoupling proteins. And
basically what those are, an uncoupling protein is just going to allow protons
(18:11):
to kind of leak across the mitochondrial membrane.
And when that happens, this regulates heat production and
metabolism. Exercise itself is going to
induce mild uncoupling in the mitochondria.
And when it does that,
because essentially the cell is looking for energy, it's
(18:34):
becoming less efficient at producing that ATP we talked about. And
because of that, because it's like, shoot, which energy system do I use? Glycolysis,
lipolysis, oxidative phosphorylation, whatever.
It's going to create metabolic flexibility and help burn fat.
And it looks like, at least in
preliminary research, that
(18:57):
slupp might influence these uncoupling
proteins. And by doing so, it's kind of
enhancing that energy expenditure. So now that you
kind of understand the mechanisms behind it, I think you can kind of
see, like, oh, you know, so when we talk about exercise memetic,
these are basically the seven things that
(19:19):
are going on. These are the checkpoints
that would normally happen when we exercise,
and these are the things that we adapt to when we see improvement in
performance or body composition or whatever.
Can you dive a little bit deeper into explaining to me
(19:41):
if it's an uncoupler? So an uncoupler is essentially burning
energy by forcing the mitochondria to work less
efficiently, but at the same time, it's causing
mitochondrial biogenesis and improvement.
Walk me through that again. And then are we also seeing
thermogenesis as it relates to this and to what
(20:04):
level? Because if we get into some well known uncouplers, like
DNP. DNP causes uncoupling in
cells throughout the body, which causes a massive amount of
thermogenesis and creates a very
significant health risk
as it relates to that, versus a targeted
(20:28):
uncoupling, which is if that
is able to do that, that's just mind blowing. Like
that is available, right? Yeah, no,
that's a really good question, and I think
definitely try to explain this a little bit better. So when we think about what's
happening, like, with an uncoupling reaction,
(20:51):
and we talk about, like, a proton leak across a mitochondrial
membrane, essentially
we're losing the ability to create as much ATP.
So our cell, and this is kind of a
oversimplification of it, but the cell kind of just like somebody would if,
you know, we were getting overwhelmed at work, you know, they start to sweat a
(21:12):
little bit, they start to panic, and pretty soon they're like, man, I'm not going
to get all this done. So I need to call in one of my coworkers.
Shoot, I need to call in three of my coworkers. And that's kind of that
mitochondrial biogenesis. So as the cell senses that there's
a demand for energy being placed upon it from
the exercise or even just the signal
(21:32):
that's coming from the slupp, and it starts to
realize it's had to switch to a less efficient energy
producing system and
that it's still having a tough time keeping up. Next thing it's
going to do is like, oh, you know what? I just need more help. So
it's going to. That's the mitochondrial biogenesis we see when there's an
(21:54):
uncoupling reaction. Essentially, the
cells are so intelligent, and they just realize that this isn't
a one man job. We're going to need two, we're going to need four, we're
going to need 816. We just need a lot of
mitochondria. Does that kind of explain it a
little bit better? Yeah, I can see why people are seeing
(22:16):
incredible results with this product. We've got, it.
Slew is signaling that, you know, we're exercising,
we need to. Yeah, yeah, the slew is signaling
that we're exercising. We need to recruit a bunch of cells. At
the same time, it's making those cells produce or use a lot
more energy than, than, than they normally would. And at
(22:39):
the same time, we've got this signaling that's also going to impact
positively muscle tissue. Um, I mean, this
is like, those mechanisms are just absolutely
incredible. I don't. Hopefully I didn't misspeak on that. You know, my,
my quick, you know, 15 2nd summary of, of
that. No, I think that was perfect. And the
(23:01):
other thing, I think that is worth clearing up for people. When we look
at SLU, pp 332 and we call it an
estrogen related receptor alpha agonist.
And of course, the first thing people are going to hear is
estrogen. And in the traditional sense,
like, well, shoot, why would I want more estrogen if my goal is to improve
(23:22):
performance, not cry? If I have to watch
rom.com with my girlfriend and whatever,
an estrogen related receptor is going to be a little bit different.
They're called that because of their structure. They're
similar in terms of structure to what an estrogen receptor
(23:44):
would look like. But the way they work, what they are, is
just completely different. Not related to hormones at all.
They're part of a family that's considered to be nuclear
receptors. Nuclear receptors essentially are
things within the nucleus of a cell that regulate genes, and
in this case, specifically, genes linked to energy production,
(24:07):
metabolism. I call them kind of switchboard
operators for how your cell is going to create and manage
energy. And with the SLU
PP, I'm just going to start calling it slew, because that's a
mouthful. With the slew, when it
activates this erra estrogen related receptor
(24:29):
alpha agonist, it's kind of like flipping this master
switch on a power plant. And once that switch
gets flipped, there's this whole cascade of metabolic processes that are
going to start rolling and supercharging your mitochondria's ability to create
energy. It's just like turning on turbo mode in your
mitochondria. So when we think about these
(24:51):
erras, let's try to think
about them in the context of just kind of being a nuclear receptor that's going
to accelerate energy production, mitochondrial
biogenesis, and all these things we're really kind of going after.
Yeah. So let's, let's talk real world. What
results have you seen from this, both personally or with people
(25:14):
using this product? Because it is hard to come by, but,
yeah, it is available to people in the,
in the know, I guess. Yeah.
Well said. I've got some experience with
it, and I really. It's interesting. So the first time I
ordered it, I got it. And when you do the
(25:36):
conversion of animal to human and
basing a dose on that, I always, especially
on something where obviously it looks really safe on paper, but
when we're talking about nuclear receptors in the
nucleus, it's serious business and we want to be pretty conservative.
So I started at 100 micrograms and
(25:58):
I. 100 micrograms. You know, I honestly didn't notice a
whole lot. And then I went up to 200
micrograms and still
wasn't really overwhelmed, went through
that bottle, and
then a month or two goes by
(26:19):
and one of the other vendors
had it available and was like, yeah, you know
what? Give it a shot. So 100 micrograms morning, 100
micrograms in pre workout
and night and day. I'm telling you, like, within ten
days, I had people asking me, like, are you dieting for something?
(26:42):
I'm like, I'm 52 years old. Like, I'm not dieting for anything, but
keeping my fiance around and not having to buy a larger
shirt. So my belly doesn't hang out. And,
I mean, it was really awesome. And I think kind of what that
speaks to is, like, you know, there's going to be these places
popping up that are going to say, hey, we got slu.
(27:04):
And, you know, just do your research on the companies. Make sure it's
a real stuff, if it's a real stuff, and
if one. My experience is it really works and it
works well. No negative effects. You know, I
get my labs run regularly, and I'm probably
a little OCD about monitoring my health. Biometrics and everything. A
(27:27):
little OCD. All right, a lot of OCD.
In fact, there's probably nobody more OCD than me. But
nothing but good stuff came from it. Like, I saw a
two point jump in my HRV, which doesn't sound significant, but my HRV is,
like, always rock bottom. So for it to go up two points,
(27:47):
I mean, it's like, even thought I stuck both fingers in a light
socket. I mean, it's. That was awesome.
And definitely, like, I mean, just, you know, I think probably everybody
does it. You wake up first thing in the morning, eyes are a little
puffy, go in front of the mirror, quick check, you know, like, how do I
look? How do I feel? And, like, the inflammation within about three days
(28:10):
was down, and within just a little over a week,
it was like, wow, you know, haven't changed my diet, haven't
changed my training, haven't changed anything except adding this
in. And I was really seeing some noticeable fat loss.
So you're suggesting 100 micrograms
twice a day and for any length of period
(28:32):
or. Yeah. Again, this
is just my personal experience with it. So,
you know, always make sure you kind of check
your own health stuff out and do your research. But
for me, 100 micrograms twice a day. I did that for
six weeks, then took six weeks off, and
(28:55):
then repeated that again. Same
protocol took twelve weeks off, and then
this time on, the protocol went up to 200
micrograms in the morning and no
afternoon dose. And that was really more or less happenstance
because just with everything
(29:17):
currently I'm involved in, it's hard to remember to take
an afternoon dose. And I didn't really notice
any difference between taking both in the morning or splitting it one on
one. And me being me.
Even pushed it up to 400 in the morning, and again,
no negative effects. In fact, like, one of
(29:39):
the things I noticed that was kind of cool as I was starting to feel,
like, a little bit run down. Not in the sense like I got a cold,
but just like man, you know. I guess mental fatigue would be the best way
to categorize it. It kind of felt like that curtain was
lifted and I was right back to normal
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Where uh, where would people be able to because
uh you have uh sourced
uh some of this to compound. Is that
(30:45):
correctly? Uh huh. Yeah. We're in the process of
kind of putting this together and going
to be working through you to kind of get this
out and give people the opportunity to check it out. If
that's something they're interested in. I think
that people are going to be really excited about this. I think they're going to
(31:08):
get the same results that I'm getting
again with any of these research
compounds. It's important to realize they are research
compounds. You know we're not, we're not making a
recommendation or anything. You know, always stay on
top of your health. But if you're curious like
(31:30):
me and this is something you're looking into doing, you know
we've tested our initial batch,
99.38% pure
and I haven't grown the third arm yet or
anything. So. Well I think doing the third party testing
is, is very critical and stuff like this. And that's the problem with you know
(31:51):
just picking you know, some of the sites that to buy that off of and
not getting because you and I both know people that have
purchased that from some sites and it's clearly not either dosed
correctly or not. There's nothing in it right. So yeah,
yeah, yeah. So long and
short. Anthony and I are working on formulating an
(32:13):
entire peptide line that is orally
bioavailable. We really believe in
peptides and their implications for being able to really
vastly change the quality of health as well as
individual performance. And so this product is something
that we're bringing out, making available so that
(32:35):
we can fund the significant amount of efforts
that have to go into developing the formulation and bringing this
to market. So if you want to find out more,
find out where to get it, go to chrisduffin.com.
join the private, join the community. And
you'll have details on where this is available.
(32:57):
So yeah. Anything to add on that?
No, just really exciting stuff. And
I'm so excited about the formulas we're working on, the
compounds we're going to be introducing. There's some real game
changers. We're really living in a time
where, you know, science is moving at the speed of thought and
(33:20):
the possibilities we have to improve people's health, performance
and outcomes. You know, the, nothing's ever going to
replace the importance of, you know, getting your rest,
training, good nutrition, hydrating, you know, the basics.
But yeah, we're speaking to and it's like I don't, you
know, I try to draw it back and make sure people know that that's
(33:42):
absolutely foundational that we recommend like get
your sleep, get your training, get your, you know, take care of
having good, you know, a diverse set of foods,
uh, you know, fundamentals. But
obviously you know I don't, it's pretty hard to I think
criticize us because our audience is people that
(34:04):
are doing those things to begin with. And so you know, constantly having to remind
that that's day one game like things that you need to
have mastered and be mastering for years before you ever, you know,
look at you know, adding anything like this. But it's
incredibly exciting. We are super excited. I've been in this space
dealing with peptides for 19 years. Actually might have been around
(34:26):
2003. Somewhere in 2003, 2005 I started getting
involved. So I incredibly passionate and
excited about this. We're also getting involved in some clinical trials
on peptides as well. So just tremendous
stuff. Sorry to interrupt you Anthony but we'd love for you
know, everyone to be a part of that in some ways. So please you know,
(34:47):
join the group and if you can support with you know,
testing out some of things like this. I can't wait to get my
hands on some sloop. Yeah it's really a
game changer. And you know if you guys have some
questions about this because I'm sure wheels are probably turning. Questions are going to come
up. Just a quick plug for
(35:09):
Chris's community. It's amazing. You know it's a great group of people
and there's people from all walks of life, all different
backgrounds and everybody's just a wealth of knowledge. Everybody's
really excited to help other people and I'm on there
answering questions. Chris is on there answering questions, everybody on there
is answering questions and asking questions. And it's a community
(35:30):
that really centers around learning, helping each other
and anything you guys have questions related
to SLU, if you join the community, post them up there. Chris and I'd
be more than happy to dig in and do the best we can to answer
your questions. Awesome. All right, that
is it.
Welcome to the architect of Resilience podcast, where
we explore the secrets of overcoming life's challenges and
unlocking unstoppable strength through deep personal
conversations and expert insights. Chris Duffin and
Anthony Kastor with you today. We have
something very exciting to dive into that probably
(00:22):
hardly anybody's heard about, because, one, it's just not available, but actually
it is. Uh, so we'll talk about that later. Uh, we just
had a nice warm up on glucose shuttling on another episode
that we randomly shot off the. Off our hip. Uh,
the. Today, I'm probably going to be doing a little bit more interview
fashion, but we're going to be covering a very unique compound.
(00:45):
It's a small molecule that is,
it's an exercise mimetic, right. And it does this by
targeting estrogen related receptors. Errs.
Uh, it's an err panel pan agonist. And that is a group
of nuclear receptors involved in regulating energy metabolism.
Mitochondrial biogenesis. Actually, I just talked about that with
(01:08):
the four hil, uh, uh, compound because there
was kind of some overlay and discussion. Uh, and oxidative,
uh, metabolism, long and short
like this is an incredible product for stripping
fat off your body, preserving muscle, and
improving metabolic health. So,
(01:31):
yeah. Do you want to give us a rundown on the key
mechanisms? Oh, I guess I haven't said what it is. What are we talking about
today, Anthony? Yeah, I'm super excited about today's
discussion. As Chris said, like, some people may have heard of it,
but not really accessible until basically now
we're going to be talking about SLU pp 332.
(01:54):
And that's not a combination to a lock or a secret code name.
It's actually secret code made to some radical fat loss
and metabolic health, but. Yeah. Yep,
exactly. And you have to have a secret knock to order
it. But other than that,
(02:14):
I think maybe before we talk about it, just kind of a quick refresher on
the mitochondria is going to make this make a lot of sense. And when we
think about our mitochondria and then being so, so crucial,
it's kind of like our body's this high performance car, like a Tesla
or Bugatti or something. And
your choice on that shoot, it could be a Corvette.
(02:37):
Mitochondria are going to be the engine. And the
better the engine is, the faster and more efficiently your car runs.
And before you ignore your engine maintenance, like the
mitochondrial health, you're going to end up running on fumes. And
no matter how shiny the exterior looks, when it comes to performance,
whether it's crushing it in the gym. Or if we're talking about, like,
(02:59):
recovering after a workout or even just living longer. Your mitochondria
are basically the unsung heroes of this. And
the way that slupp 332 is going to fit into this
is a couple different things. It's an exercise memetic,
which is fascinating in and of itself. We'll talk about that a little
bit, and basically what that means.
(03:22):
Exercise memetics can
essentially mimic some of the effects of exercise without
having to do the actual workout. So, kind of imagine, like,
you're getting some of the benefits of a jog while you're
binge watching Netflix. I know for a lot of people, that probably sounds
pretty, pretty appealing, and at the same time, it's like, well, how can I
(03:45):
do that? And definitely, it's doing
that by causing an
increase in the mitochondrial function and enhancing energy
expenditure. So just like going for a
jog would, right. And in essence, doing
a set of bench press is going to do the same thing, but it's
(04:07):
clearly not going to do. The effect of the other aspects
of doing a bench press workout are going to be. So when
we say s exercise mimedic, we're talking about the enhanced energy
expenditure of a workout. Yeah. And it
definitely doesn't take the place of working out. It's just something that if you're
already doing the right things in the gym, it's going to
(04:29):
improve your. Your results and all
that good stuff. As you mentioned, Chris, it's going to
boost the mitochondrial function. And I also helps with
mitochondrial biogenesis. What that means when we think about
biogenesis, you're creating more mitochondria.
And when we do this, since each of those, as we recall, are
(04:52):
essentially like the horsepower of the engine of our car, now we've
got two engines in that Bugatti instead of
one. So it's going to be even faster and perform even
better. And scientists are getting really excited
about this one. It's going to have application
for metabolic disorders, muscle
(05:14):
atrophy, cognitive decline. It's
almost like they found a way to biohack ourselves. I hate to use that word,
but we're really on the cusp of something great.
Every time I hear somebody say biohack, I think of Dave Asprey without his
shirt off in his office, crunching. So his abs are flexed,
but he's got this weird look like this. You know what I'm talking about?
(05:43):
Sorry. No, I know
exactly what you're talking about. And I get the same visual. I think that's probably
why I don't like the word,
I think, to maybe help people understand, like when we talk about
exercise, memetic, sort of what's happening on a cellular level, if we kind
(06:04):
of break it down, might
put a little bit more context to it. So
the first thing is AMPK,
and that's going to be like the Amp activated protein
kinase. And the way to think about that is
Ampk is like the cell's energy gauge
(06:25):
and it's going to be activated if the cell
senses low energy. So like
higher levels of ampk compared to ATP,
adenosine monophosphate one compared to adenosine
triphosphate three. And that's something that
happens, like during exercise because we're using up that
(06:47):
ATP. And when you work out, energy
stores are going to be depleted and AMPK gets
switched on and tells your cells to generate more ATP by burning
fat. This is going to also help with
increasing glucose uptake, enhancing mitochondrial
function. And it's almost like putting your cells in this energy
(07:08):
efficient mode. And the way that SLU PP
332 mimics it is it
directly activates this amPk, even without
exercise, and it makes the cell think that it's on this low
energy. So this is going to cause the cell to
react as if it's in a state of this,
(07:29):
like, whoa, I'm exercising, you know, I don't have enough energy here
and it's going to improve those metabolic processes and energy
production, almost like a survival mechanism. Let's dive into the
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(08:15):
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code resilience for 10% off. So with
that, we had another discussion where we're talking about that and that
relation to, to mtor as well.
Is there some timing that we need to think about
with the use of this for impacting, uh,
(08:37):
uh, mtor and muscle protein synthesis? Because
obviously the energy sensing. So sensing this low energy
levels is going to help improve the mitochondrial
function using inner, you know, using those resources. So it's going to help
with body composition, right. We're going to get leaner, we're going to retain
muscle mass, but at the same time, if.
(08:59):
If we have mtor shutdown, we're not going to be able to add
muscle mass quite as, uh, effectively, uh, you know,
because muscle protein synthesis requires
massive amounts of energy. And so
when we. When the cell sense low energy like that processes
is essentially kind of shuttled.
(09:21):
Yeah, no, that's a really good point. And the research is
pretty new on this. Most of what you're going to find
is going to be n of one, where people are
reporting their experience with it, and we'll get into some of that
or a lot of animal data.
(09:41):
Personally, my thoughts are it would be something I'd use in the morning
and then prior to a workout, probably about an hour before,
some other things it does. And this will kind of explain my timing behind
it. Well, first, I just. I would put the caveat that
anybody using this is probably doing some sort of hormonal
(10:04):
optimization as a whole anyway, which then would kind of counter
those effects as well. Right. If you're doing some things to,
you know, stimulate growth hormone relief, release or maintain
estrogen levels or some sort of, you know, hormonal
enhancement, it became pretty irrelevant. Just
like, you know, in prior discussion, we talked about, you know, bodybuilders,
(10:26):
professional bodybuilders using metformin. We don't
seem to be lacking any sort of muscle mass on an IFBB pro
using metformin, although at times they still try to,
you know, you know, put that at certain times as it
relates to, um, to training, but others
probably don't, you know, because, again, I having poor
(10:49):
energy metabolism. So a bodybuilder may be doing that because they
have so much androgens in their system
that they've got a level of insulin
resistance developing. And so they may be taking
the metformin to counter that or to help with the
carb displacement, but similar effects with that as it
(11:12):
relates to energy sensing
and the ampk signaling side
of that, some similar thought processes. So just context, right?
Just going context doesn't mean,
but something to be aware of. Yeah,
(11:33):
one of the things, and this will kind of tie into the mtor that's
really cool about the SLU. Pp 332
is it also activates PGC one
alpha. And what that is, it's this master regulator of
mitochondrial biogenesis. And it
kind of turns the dial up when we need to produce more mitochondria
(11:55):
and especially like, during exercise or endurance, endurance training
and with that being kind of a regulator.
And then the other thing, it does, too, it
activates sirtuitin one protein.
And when we exercise and, like,
(12:15):
nad levels increase, this also activates
sirtuitin one. And those are, again, things that are going to help
modulate that mitochondrial function, reduce oxidative stress,
and promote the cellular repair. What's unique about
it, though, with regards to the mtoR. So that's
almost going to bypass a lot of what I'm talking about, because it's going to
(12:38):
create some of those same effects
again, like a hormonal would with preserving or growing muscle
tissue, especially mitochondrial biogenesis.
Yeah. When we think about, like, mtor being
kind of the pathway that regulates the cell growth, protein synthesis, muscle building,
all that good stuff. And then, of course, with
(13:00):
exercise, you know, we're activating that mtor pathway, and
the slupp 332 actually mimics
it. And the way that it does this is kind of unique.
It does this through endurance based pathways like the
AMPK and PGC One Alpha.
And it's kind of an indirect effect on energy balance,
(13:22):
which interacts with the mTOR and
promotes better recovery and health, kind of to untangle that,
because I know that's kind of a complicated explanation
if you think about an endurance runner. And obviously, you know, they're
not massive muscle or anything, but
by running, they're going to build muscle. So. And that
(13:44):
comes through, like, an mtor activation, even though they're primarily
ampk. So when we look at how
slupp 332 is working indirectly, you're getting
kind of that same mtor stimulation
that you'd see in an endurance athlete. And I don't
want people to read too much into that, like, oh, man, it's going to build
(14:05):
slow twitch fibers or whatever. No, it's just there's kind
of more than. More than one way to get to the same
end. So by taking this indirect route to
stimulate the mtor, you're kind of getting the best of both worlds. You're getting
the improved energy metabolism
and activation of the PGC one output, which is going to kind of
(14:27):
regulate everything. And you're getting the
mtor signaling as well. Wow, that's pretty wild. That makes
that just substantially different than anything else that we've
talked about in these classes. Yeah, that's. Yeah,
that's amazing. Truly unique. Yeah. The other thing that it
does, it's kind of interesting, is, like, with the
(14:50):
calcium signaling. So calcium ions are going to act like
signaling molecules in a lot of cellular processes. Like, when we think about
muscle contraction or mitochondrial function. And
during exercise, these calcium levels kind of fluctuate,
and this signals the mitochondria to increase energy
production. So it's meeting that higher demand as it's sensing, like,
(15:12):
these fluctuations in calcium.
What slupp 332 does is
it can affect the calcium signaling pathway,
and it's kind of cool. It tricks these cells into thinking
they're in an exercise state, and then this is going to lead to
enhanced mitochondrial activity and energy output.
(15:35):
So, essentially to kind of unpack that when
we're thinking about every time we contract our
muscle. And I just kind of imagine, like, this tidal wave of calcium going up
and down, and our body trying to make heads or sense of that, or heads
or tails of that and draw some sense from it. The
SLU essentially is kind of telling the body what's happening. Like, all right,
(15:57):
you know, we need a little bit more energy. Calcium is doing this. And
so just kind of another way it's supporting that plays into that
exercise memetic effect that we're talking about.
Then the final thing that's super important to mention
is its effect on reactive oxygen species and the antioxidant
process. So we know, like, when we exercise, we want to have a certain amount
(16:20):
of oxidative stress. And Chris and
I just talked about it and not too long ago, and he
pointed out that, and I agree 100%, that if you
put out the flame, the oxidation
too soon after the workout, you don't stimulate that inflammation. Essentially,
you're just putting a wet blanket over your gains. So we want to have those,
(16:43):
but the key is we want to be able to kind of switch that off
when we need to. And these reactive
oxygen species are basically byproducts of mitochondrial activity,
and they can cause oxidative damage if they're left
unchecked. So during your workout, your
cells basically are going to generate more of these, and
(17:05):
it's going to allow them to become more resilient.
They start producing antioxidants like
glutathione. And that kind of improves the cellular
process. So what the SLU does is it
increases the mitochondrial activity and energy production,
and it increases reactive oxygen species
(17:27):
production in a controlled way. And that's the key in a controlled
way, and that stimulates the cell's antioxidant
defense. So essentially, it's not letting too much out that we're
getting those reactive oxygen species, but it's letting enough that we're
maximizing or that we can kind of calibrate
our glutathione production. So we're putting out just enough of
(17:48):
that fire, but still getting the signal to
adapt and make progress.
And then the other mechanism of action,
and this is one of my favorite areas to kind of
look into uncoupling proteins. And
basically what those are, an uncoupling protein is just going to allow protons
(18:11):
to kind of leak across the mitochondrial membrane.
And when that happens, this regulates heat production and
metabolism. Exercise itself is going to
induce mild uncoupling in the mitochondria.
And when it does that,
because essentially the cell is looking for energy, it's
(18:34):
becoming less efficient at producing that ATP we talked about. And
because of that, because it's like, shoot, which energy system do I use? Glycolysis,
lipolysis, oxidative phosphorylation, whatever.
It's going to create metabolic flexibility and help burn fat.
And it looks like, at least in
preliminary research, that
(18:57):
slupp might influence these uncoupling
proteins. And by doing so, it's kind of
enhancing that energy expenditure. So now that you
kind of understand the mechanisms behind it, I think you can kind of
see, like, oh, you know, so when we talk about exercise memetic,
these are basically the seven things that
(19:19):
are going on. These are the checkpoints
that would normally happen when we exercise,
and these are the things that we adapt to when we see improvement in
performance or body composition or whatever.
Can you dive a little bit deeper into explaining to me
(19:41):
if it's an uncoupler? So an uncoupler is essentially burning
energy by forcing the mitochondria to work less
efficiently, but at the same time, it's causing
mitochondrial biogenesis and improvement.
Walk me through that again. And then are we also seeing
thermogenesis as it relates to this and to what
(20:04):
level? Because if we get into some well known uncouplers, like
DNP. DNP causes uncoupling in
cells throughout the body, which causes a massive amount of
thermogenesis and creates a very
significant health risk
as it relates to that, versus a targeted
(20:28):
uncoupling, which is if that
is able to do that, that's just mind blowing. Like
that is available, right? Yeah, no,
that's a really good question, and I think
definitely try to explain this a little bit better. So when we think about what's
happening, like, with an uncoupling reaction,
(20:51):
and we talk about, like, a proton leak across a mitochondrial
membrane, essentially
we're losing the ability to create as much ATP.
So our cell, and this is kind of a
oversimplification of it, but the cell kind of just like somebody would if,
you know, we were getting overwhelmed at work, you know, they start to sweat a
(21:12):
little bit, they start to panic, and pretty soon they're like, man, I'm not going
to get all this done. So I need to call in one of my coworkers.
Shoot, I need to call in three of my coworkers. And that's kind of that
mitochondrial biogenesis. So as the cell senses that there's
a demand for energy being placed upon it from
the exercise or even just the signal
(21:32):
that's coming from the slupp, and it starts to
realize it's had to switch to a less efficient energy
producing system and
that it's still having a tough time keeping up. Next thing it's
going to do is like, oh, you know what? I just need more help. So
it's going to. That's the mitochondrial biogenesis we see when there's an
(21:54):
uncoupling reaction. Essentially, the
cells are so intelligent, and they just realize that this isn't
a one man job. We're going to need two, we're going to need four, we're
going to need 816. We just need a lot of
mitochondria. Does that kind of explain it a
little bit better? Yeah, I can see why people are seeing
(22:16):
incredible results with this product. We've got, it.
Slew is signaling that, you know, we're exercising,
we need to. Yeah, yeah, the slew is signaling
that we're exercising. We need to recruit a bunch of cells. At
the same time, it's making those cells produce or use a lot
more energy than, than, than they normally would. And at
(22:39):
the same time, we've got this signaling that's also going to impact
positively muscle tissue. Um, I mean, this
is like, those mechanisms are just absolutely
incredible. I don't. Hopefully I didn't misspeak on that. You know, my,
my quick, you know, 15 2nd summary of, of
that. No, I think that was perfect. And the
(23:01):
other thing, I think that is worth clearing up for people. When we look
at SLU, pp 332 and we call it an
estrogen related receptor alpha agonist.
And of course, the first thing people are going to hear is
estrogen. And in the traditional sense,
like, well, shoot, why would I want more estrogen if my goal is to improve
(23:22):
performance, not cry? If I have to watch
rom.com with my girlfriend and whatever,
an estrogen related receptor is going to be a little bit different.
They're called that because of their structure. They're
similar in terms of structure to what an estrogen receptor
(23:44):
would look like. But the way they work, what they are, is
just completely different. Not related to hormones at all.
They're part of a family that's considered to be nuclear
receptors. Nuclear receptors essentially are
things within the nucleus of a cell that regulate genes, and
in this case, specifically, genes linked to energy production,
(24:07):
metabolism. I call them kind of switchboard
operators for how your cell is going to create and manage
energy. And with the SLU
PP, I'm just going to start calling it slew, because that's a
mouthful. With the slew, when it
activates this erra estrogen related receptor
(24:29):
alpha agonist, it's kind of like flipping this master
switch on a power plant. And once that switch
gets flipped, there's this whole cascade of metabolic processes that are
going to start rolling and supercharging your mitochondria's ability to create
energy. It's just like turning on turbo mode in your
mitochondria. So when we think about these
(24:51):
erras, let's try to think
about them in the context of just kind of being a nuclear receptor that's going
to accelerate energy production, mitochondrial
biogenesis, and all these things we're really kind of going after.
Yeah. So let's, let's talk real world. What
results have you seen from this, both personally or with people
(25:14):
using this product? Because it is hard to come by, but,
yeah, it is available to people in the,
in the know, I guess. Yeah.
Well said. I've got some experience with
it, and I really. It's interesting. So the first time I
ordered it, I got it. And when you do the
(25:36):
conversion of animal to human and
basing a dose on that, I always, especially
on something where obviously it looks really safe on paper, but
when we're talking about nuclear receptors in the
nucleus, it's serious business and we want to be pretty conservative.
So I started at 100 micrograms and
(25:58):
I. 100 micrograms. You know, I honestly didn't notice a
whole lot. And then I went up to 200
micrograms and still
wasn't really overwhelmed, went through
that bottle, and
then a month or two goes by
(26:19):
and one of the other vendors
had it available and was like, yeah, you know
what? Give it a shot. So 100 micrograms morning, 100
micrograms in pre workout
and night and day. I'm telling you, like, within ten
days, I had people asking me, like, are you dieting for something?
(26:42):
I'm like, I'm 52 years old. Like, I'm not dieting for anything, but
keeping my fiance around and not having to buy a larger
shirt. So my belly doesn't hang out. And,
I mean, it was really awesome. And I think kind of what that
speaks to is, like, you know, there's going to be these places
popping up that are going to say, hey, we got slu.
(27:04):
And, you know, just do your research on the companies. Make sure it's
a real stuff, if it's a real stuff, and
if one. My experience is it really works and it
works well. No negative effects. You know, I
get my labs run regularly, and I'm probably
a little OCD about monitoring my health. Biometrics and everything. A
(27:27):
little OCD. All right, a lot of OCD.
In fact, there's probably nobody more OCD than me. But
nothing but good stuff came from it. Like, I saw a
two point jump in my HRV, which doesn't sound significant, but my HRV is,
like, always rock bottom. So for it to go up two points,
(27:47):
I mean, it's like, even thought I stuck both fingers in a light
socket. I mean, it's. That was awesome.
And definitely, like, I mean, just, you know, I think probably everybody
does it. You wake up first thing in the morning, eyes are a little
puffy, go in front of the mirror, quick check, you know, like, how do I
look? How do I feel? And, like, the inflammation within about three days
(28:10):
was down, and within just a little over a week,
it was like, wow, you know, haven't changed my diet, haven't
changed my training, haven't changed anything except adding this
in. And I was really seeing some noticeable fat loss.
So you're suggesting 100 micrograms
twice a day and for any length of period
(28:32):
or. Yeah. Again, this
is just my personal experience with it. So,
you know, always make sure you kind of check
your own health stuff out and do your research. But
for me, 100 micrograms twice a day. I did that for
six weeks, then took six weeks off, and
(28:55):
then repeated that again. Same
protocol took twelve weeks off, and then
this time on, the protocol went up to 200
micrograms in the morning and no
afternoon dose. And that was really more or less happenstance
because just with everything
(29:17):
currently I'm involved in, it's hard to remember to take
an afternoon dose. And I didn't really notice
any difference between taking both in the morning or splitting it one on
one. And me being me.
Even pushed it up to 400 in the morning, and again,
no negative effects. In fact, like, one of
(29:39):
the things I noticed that was kind of cool as I was starting to feel,
like, a little bit run down. Not in the sense like I got a cold,
but just like man, you know. I guess mental fatigue would be the best way
to categorize it. It kind of felt like that curtain was
lifted and I was right back to normal
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Where uh, where would people be able to because
uh you have uh sourced
uh some of this to compound. Is that
(30:45):
correctly? Uh huh. Yeah. We're in the process of
kind of putting this together and going
to be working through you to kind of get this
out and give people the opportunity to check it out. If
that's something they're interested in. I think
that people are going to be really excited about this. I think they're going to
(31:08):
get the same results that I'm getting
again with any of these research
compounds. It's important to realize they are research
compounds. You know we're not, we're not making a
recommendation or anything. You know, always stay on
top of your health. But if you're curious like
(31:30):
me and this is something you're looking into doing, you know
we've tested our initial batch,
99.38% pure
and I haven't grown the third arm yet or
anything. So. Well I think doing the third party testing
is, is very critical and stuff like this. And that's the problem with you know
(31:51):
just picking you know, some of the sites that to buy that off of and
not getting because you and I both know people that have
purchased that from some sites and it's clearly not either dosed
correctly or not. There's nothing in it right. So yeah,
yeah, yeah. So long and
short. Anthony and I are working on formulating an
(32:13):
entire peptide line that is orally
bioavailable. We really believe in
peptides and their implications for being able to really
vastly change the quality of health as well as
individual performance. And so this product is something
that we're bringing out, making available so that
(32:35):
we can fund the significant amount of efforts
that have to go into developing the formulation and bringing this
to market. So if you want to find out more,
find out where to get it, go to chrisduffin.com.
join the private, join the community. And
you'll have details on where this is available.
(32:57):
So yeah. Anything to add on that?
No, just really exciting stuff. And
I'm so excited about the formulas we're working on, the
compounds we're going to be introducing. There's some real game
changers. We're really living in a time
where, you know, science is moving at the speed of thought and
(33:20):
the possibilities we have to improve people's health, performance
and outcomes. You know, the, nothing's ever going to
replace the importance of, you know, getting your rest,
training, good nutrition, hydrating, you know, the basics.
But yeah, we're speaking to and it's like I don't, you
know, I try to draw it back and make sure people know that that's
(33:42):
absolutely foundational that we recommend like get
your sleep, get your training, get your, you know, take care of
having good, you know, a diverse set of foods,
uh, you know, fundamentals. But
obviously you know I don't, it's pretty hard to I think
criticize us because our audience is people that
(34:04):
are doing those things to begin with. And so you know, constantly having to remind
that that's day one game like things that you need to
have mastered and be mastering for years before you ever, you know,
look at you know, adding anything like this. But it's
incredibly exciting. We are super excited. I've been in this space
dealing with peptides for 19 years. Actually might have been around
(34:26):
2003. Somewhere in 2003, 2005 I started getting
involved. So I incredibly passionate and
excited about this. We're also getting involved in some clinical trials
on peptides as well. So just tremendous
stuff. Sorry to interrupt you Anthony but we'd love for you
know, everyone to be a part of that in some ways. So please you know,
(34:47):
join the group and if you can support with you know,
testing out some of things like this. I can't wait to get my
hands on some sloop. Yeah it's really a
game changer. And you know if you guys have some
questions about this because I'm sure wheels are probably turning. Questions are going to come
up. Just a quick plug for
(35:09):
Chris's community. It's amazing. You know it's a great group of people
and there's people from all walks of life, all different
backgrounds and everybody's just a wealth of knowledge. Everybody's
really excited to help other people and I'm on there
answering questions. Chris is on there answering questions, everybody on there
is answering questions and asking questions. And it's a community
(35:30):
that really centers around learning, helping each other
and anything you guys have questions related
to SLU, if you join the community, post them up there. Chris and I'd
be more than happy to dig in and do the best we can to answer
your questions. Awesome. All right, that
is it.
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