Blood & Cancer

Blood & Cancer

The official podcast feed of MDedge Hematology-Oncology, part of the Medscape Professional Network. Shows types include hem/onc news and clinical interviews hosted by Dr. David Henry, MD. The interviews feature key opinion leaders and rising stars in hematology and oncology. The information in this podcast is provided for informational and educational purposes only.... Show More

Episodes

September 24, 2020 23 min

How do patients fare when they have cancer and COVID-19? Researchers developed the COVID-19 and Cancer Consortium (CCC19) and the National Cancer Institute COVID-19 in Cancer Patients Study (NCCAPS) to gain some insight.

In this episode, Brian Rini, MD, a professor of medicine at Vanderbilt University Medical Center, Nashville, Tenn., and host of The Uromigos podcast, explains what CCC19 and NCCAPS are. He also discusses findings f...

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This week in Hematology and Oncology news:

  • Large waistline linked to higher risk of prostate cancer death (https://bit.ly/3iRxmya)
  • FOLFOXRI tops doublets as bevacizumab backbone for mCRC (https://bit.ly/32QpTKi)

  • AI algorithm on par with radiologists as mammogram reader (https://bit.ly/35WnAXV)

  • How I Treat: For low-risk MDS, treat 'what bugs patients most' (https://bit.ly/2ZU5TEU)
  •  

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    Find more Blood & Cancer at htt...

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    How has COVID-19 impacted medical students? Two students from Royal College of Surgeons in Ireland (RCSI), Dublin, describe their experiences in this episode.

    Evani Patel and Sarah Chen, both second-year medical students at RCSI, tell host David H. Henry, MD, how the COVID-19 pandemic has shaped their educational experience thus far.

    Now, the pandemic has shifted the students’ education to a mix of virtual and in-person learning at...

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    Hematology/Oncology News:

  • Study supports multigene panel testing for all breast cancer patients with second primary cancers: https://bit.ly/3m6RyOG
    Source: https://bit.ly/2ZKXund

  • Atezolizumab TNBC indication ‘in jeopardy’ because of phase 3 results: https://bit.ly/35rqzrl
    Alert: https://bit.ly/2Reh1HM
    Trial: https://bit.ly/2ZqqIqX

  • Pralsetinib: Second drug for RET+ NSCLC approved in U.S.: https://bit.ly/3bTdGaz

  • Unexpected resu...

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    Treatment strategies for myelodysplastic syndromes (MDS) vary widely depending upon patients’ prognosis. In this episode, Shannon R. McCurdy, MD, of the University of Pennsylvania, Philadelphia, joined host David H. Henry, MD, to discuss how she treats patients with MDS.

    To start, Dr. McCurdy evaluates patients using the revised International Prognostic Survival Scale (IPSS-R), which can predict the aggressiveness of MDS.

  • Low IPSS-...
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    Blood & Cancer News:  
  • Delaying RT for higher-risk prostate cancer found safe: https://bit.ly/2F1cKoQ
    Source: https://bit.ly/2FaaMCr
    RTOG 9413: https://bit.ly/2DL2FM4
    RTOG 9910: https://bit.ly/2F8itJe
  • HOME-PE trial clarifies which pulmonary embolism patients to treat at home: https://bit.ly/3ibNTN9

  • Melanoma experts say ‘no’ to routine gene profile testing: https://bit.ly/2Zka10p
    Source: https://bit.ly/2ZkzerB 

  • VTE, sepsis risk i...
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    Episode 94 features the best of ASCO 2020, and we'll see you all with new content for episodes 95 and 96. 

    *  *  *

    Best of:

  • How did it go? Nick Andrews and David Henry, MD, discuss how Dr. Henry thought the meeting went from episode 73. 

  • Top five abstracts. Dr. Henry and Alan Lyss, MD, discuss their top five abstracts each from episode 74. 

  • Preview/review. Howard "Skip" Burris, III, MD, joined Dr. Henry to talk about ho...
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    MDedge Hematology-Oncology news for the first week of September 2020. 

  • Aspirin may accelerate cancer progression in older adults: https://bit.ly/2ENHRUc
    ASPREE trial: https://bit.ly/2QAsMYW
    Meta-analysis: https://bit.ly/2D6rXnl
    AsCaP: https://bit.ly/2G06X2I
  • Black/White gap gone: ‘The only cancer where this has happened’: https://bit.ly/3jm8PBm
    Source: https://bit.ly/3lv4u0m
  • Selpercatinib 'poised to alter the landscape' of RET...
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    The SECURE-SCD registry was designed to collect and disseminate information on patients with sickle cell disease (SCD) who develop COVID-19.

    Two of the registry’s organizers are Amanda Brandow, DO, and Julie Panepinto, MD, both of the Medical College of Wisconsin/Children’s Wisconsin in Milwaukee.

    In this episode, Dr. Brandow and Dr. Panepinto discuss SECURE-SCD and its findings with host David H. Henry, MD.

    SECURE-SCD is an onlin...

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    News for the week of August 24, 2020. 

  • Beyond baseline, DBT no better than mammography for dense breasts: https://bit.ly/2FTRnpp
    Study source: https://bit.ly/2FTLkkI
    Lead author: https://bit.ly/3graAv0
  • Subgroups predict adjuvant chemoradiotherapy benefits in low-grade glioma: https://bit.ly/31oHkkr
    Source: https://bit.ly/3aSVe1j
  • Diabetes plus weight loss equals increased risk of pancreatic cancer: https://bit.ly/2Etmbws
    Source: https...
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    Dr. David Henry welcomes NBA power forward Mason Plumlee. Plumlee, who is now participating in the NBA's controlled COVID-19 environment, affectionately referred to as the "bubble," tested positive for COVID-19 before we knew that loss of taste and smell was a symptom. 

    In a wellness and intellectual change-of-pace episode, Plumlee joins Dr. Henry to talk about his background in medicine and biology, his experiences in ...

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    Hematology-Oncology news:

  • Chemo-free management of mesothelioma on horizon: https://bit.ly/2CyL6xY
    CheckMate 743: https://bit.ly/2CBy6HX
    INITIATE trial: https://bit.ly/3axxdg8
    MAPS2: https://bit.ly/32hWCa0
  • FDA approves first liquid biopsy/NGS test for lung cancer: https://bit.ly/3258jRn
  • Swallowable 'sponge on a string' to diagnose esophageal cancer: https://bit.ly/3iUbLFb
    Source: https://bit.ly/2Q0T6en
  • COVID-19 impact: Less ch...
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    Hanny Al-Samkari, MD, joins the podcast to discuss thrombosis in COVID-19 and lung cancer patients as well as the use of bevacizumab in patients with hereditary hemorrhagic telangiectasia (HHT).

    Dr. Al-Samkari, of Massachusetts General Hospital, presented three studies on these topics at the virtual ISTH 2020 Congress. In this episode, Dr. Al-Samkari describes these studies to host David H. Henry, MD.

  • Thrombosis, Bleeding, and the...
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    Subscribe to Blood & Cancer: Apple PodcastsSpotifyGoogle Podcasts

    This week in HemOnc news:

  • Study: Immune checkpoint inhibitors don't increase risk of death in cancer patients with COVID-19: https://bit.ly/2PEttQa
  • System provides 'faster, less invasive' method for breast cancer detection: https://bit.ly/3achral
    Source: https://bit.ly/3gN507j
  • FDA approves belantamab in relapsed/refractory multiple myeloma: https://...
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    How does the community oncologist treat multiple myeloma? Gustavo A. Fonseca, MD, of Florida Cancer Specialists, shares his approach to myeloma treatment with host David H. Henry, MD.

    At the start of this episode, Dr. Fonseca and Dr. Henry discuss their love of podcasts, mentioning shows that have proven useful to them personally and professionally.

    The pair then move on to discuss hypothetical myeloma cases and advances in treatme...

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    Subscribe to Blood & Cancer: Apple Podcasts, Spotify, Google Podcasts

     

    This week in HemOnc News:

  • Higher death rate seen in cancer patients with nosocomial COVID-19
    Article: https://bit.ly/2XjRLDq
    Source: https://bit.ly/3goLGgF
  • Robotic renal surgery bests open partial nephrectomy
    Article: https://bit.ly/2PhHS4M
    Source: https://bit.ly/3gqXXBd

  • Large cohort study: Bevacizumab safe, effective for severe HHT bleeds
    Article: http...

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    COVID-19 can have a negative impact on systems throughout the body, beyond just the lungs, according to a review published in Nature Medicine. Two authors of the review joined host David H. Henry, MD, to discuss their article, “Extrapulmonary manifestations of COVID-19.” 

    Aakriti Gupta, MD, of Columbia University Irving Medical Center, and Kartik Sehgal, MD, of Dana Farber Cancer Institute, discussed:

  • ACE2, the entry receptor for ...
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    Subscribe to Blood & Cancer: Apple Podcasts, Spotify, Google Podcasts

    This week in HemOnc News:

  • PSMA PET/CT may be new 'gold standard' for prostate cancer staging
    Source: https://bit.ly/2CRaq2t
    Study: https://bit.ly/3f18YHL

  • Analysis of early-onset cancer suggests need for genetic testing
    Source: https://bit.ly/2WZSIR3
    AACR Abstract: https://bit.ly/3f18YHL

  • Early screening may halve breast cancer mortality in childhood ca...
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    While relaxing on the Jersey Shore, host and MDedge Hematology/Oncology Editor-in-Chief, David Henry, MD, dove into the July 10, 2020, issue of the Journal of Clinical Oncology. In episode 82, we do the same.

     

    J Clin Oncol. 2020 Jul 10. 38(20). 2217-2361. (https://bit.ly/2ZQEJ27)

     

    You can follow along with the following articles:

  • Lumpectomy Margins for Invasive Breast Cancer and Ductal Carcinoma in Situ: Current Guideline Re...
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    The latest news from MDedge Hematology/Oncology: 

    In this episode: 

  • MRI reliably identifies significant prostate cancer
    * Original MDedge article (https://bit.ly/3hgKT1h)
    * PROMIS analysis (https://bit.ly/3fLOiEN)
  • Drug-drug interactions to avoid in patients with GI cancer
    * Original MDedge article (https://bit.ly/39eHi0G)
  • ctDNA clearance tracks with PFS in NSCLC subtype
    * Original MDedge article (https://bit.ly/3eJKm6o)
    * Abstract fr...
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