A Cleveland Clinic podcast exploring heart, vascular and thoracic topics of interest to healthcare providers: medical and surgical treatments, diagnostic testing, medical conditions, and research, technology and practice issues.
Kenneth McCurry, MD, and Marie Budev, DO, share Cleveland Clinic’s multidisciplinary approach to managing end-stage lung disease and advancing lung transplantation. They discuss innovations such as ex vivo lung perfusion (EVLP), ECMO bridging, and strategies for expanding donor and recipient criteria, including complex and multi-organ cases. The episode also highlights ongoing research and clinical trials aimed at improving post-tr...
Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce Cleveland Clinic’s Cardioimmunology Center, a new initiative focused on the intersection of immune pathways and cardiovascular disease. They discuss how immune system activity can influence heart health and discuss innovative approaches to identifying and managing cardiovas...
Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, discuss a multidisciplinary approach to peripheral artery disease (PAD) management. They explore evidence-based strategies including early detection, optimal medical therapy, supervised exercise programs and advanced endovascular and surgical interventions, emphasizing team-based care and longitudinal follow-up for improved outcomes.
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Allan Klein, MD, and Tom Kai Ming Wang, MBChB, discuss the 2025 ACC Concise Clinical Guidance on pericardial disease. They explore updated diagnostic criteria, the role of multimodality imaging and a shift toward IL-1 blockers for recurrent pericarditis. Learn practical strategies to optimize patient outcomes and avoid misdiagnosis or undertreatment, along with insights on surgical options and emerging clinical trials.
Rea...
Lars Svensson, MD, PhD, and Xiaoying Lou, MD, share a deep dive into valve-sparing aortic root surgery, an advanced technique that preserves the patient’s native valve while treating aortic aneurysms.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides, with promising safety and efficacy data that could reshape lipid management.
Learn more about C5 Research at Cleveland Clinic.
https://my.clevelandclinic.org/research/c5research...
A. Marc Gillinov, MD, and Tarek Malas, MD, discuss the long-term benefits of mitral valve repair for patients with degenerative mitral valve disease. They explore surgical decision-making, robotic techniques and post-operative recovery strategies like cardiac rehab that support lifelong valve function and optimal patient outcomes.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a...
Kenneth McCurry, MD, and Marie M. Budev, DO, discuss Cleveland Clinic’s leadership in lung and multi-organ transplantation, highlighting innovations like ex vivo lung perfusion (EVLP) and the collaborative care model that supports complex transplant cases. They also acknowledge Lung Transplant Awareness Day, a national initiative aimed at increasing education about end-stage lung disease.
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Tamanna Singh, MD, and Amanda Vest, MBBS, discuss the relationship between obesity and heart failure. They discuss multidisciplinary strategies, including lifestyle interventions and pharmacologic therapies like GLP-1 receptor agonists for managing patients across the spectrum of heart failure. Learn emerging clinical research regarding obesity and heart failure from Cleveland Clinic experts.
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Donna Kimmaliardjuk, MD, and Faisal Bakaeen, MD, explore the latest in multi-arterial coronary artery bypass grafting (CABG). They discuss patient selection, surgical techniques and long-term outcomes supported by optimal medical therapy.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
When a heart is weak after a heart attack, cardiac arrest or surgery, mechanical circulatory support (MCS) can help the heart function while it heals or assist patients long-term. Cleveland Clinic experts discuss MCS devices, specifically the Impella percutaneous left ventricular assist device (LVAD) and extracorporeal membrane oxygenation (ECMO).
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Amanda Vest, MBBS, explores sex-based differences in heart failure, focusing on biological and social factors that influence disease development, treatment response and outcomes in women. She highlights disparities in risk factors, access to care and clinical trial representation that can influence heart failure outcomes.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p...
Scott Cameron, MD, highlights the underdiagnosis and undertreatment of peripheral artery disease (PAD) in women. He discusses diagnostic challenges and emphasizes the need for improved screening, female-specific guidelines and more inclusive research to address disparities in care.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Women are more likely than men to experience atrial fibrillation symptoms. Mohamed Kanj, MD, discusses gender-based differences in atrial fibrillation treatment, including rate control, rhythm control and anticoagulation.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Ravi Ambani, MD, and Aravinda Nanjundappa, MBBS, MD, discuss Cleveland Clinic’s leadership and progress in treating carotid artery disease. Learn how multidisciplinary teams are transforming care with new research on medical and surgical therapies.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pulmonary hypertension caused by chronic blood clots in the lungs. It is an under-recognized condition, but with accurate imaging and quality treatment, it can often be cured. Gustavo Heresi, MD, and Michael Tong, MD, discuss diagnosis, medical therapy and surgical options for people with CTEPH.
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When treating mitral valve disease, a surgeon must decide whether to repair or replace a valve. Cleveland Clinic experts discuss robotically-assisted surgery, reoperations and the outcomes a patient can expect from surgery at Cleveland Clinic.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Meet the presenters:
Marc Gillinov, MD, He...
Connective tissue disorders like Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes can affect the function of the heart and aorta. Cleveland Clinic experts discuss surgical options, recovery and expected outcomes for those with connective tissue disorders.
Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Meet the Presenters:
Lars Sven...
Connective tissue disorders like Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes can affect the function of the heart and aorta. Cleveland Clinic experts discuss the diagnosis of these genetic conditions and indications for heart and aorta treatment in patients with connective tissue disorders in part one of this two-part series.
Meet the Presenters:
Lars Svensson, MD, PhD
Chief of the Sydell and Arnold Miller Fa...
G. Jay Bishop, MD, and Aravinda Nanjundappa, MBBS, MD, explore Cleveland Clinic’s latest advances in vascular medicine, from research on aortic aneurysm biomarkers to innovative treatments for pulmonary embolism, hypertension, and peripheral artery disease. Learn how multidisciplinary teams are transforming care with new research on cutting-edge therapies.
Looking to refer a patient? Please reach out to our Physician Refe...
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