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April 1, 2025

We discuss the injuries sustained from smoke inhalation.

Hosts:
Sarah Fetterolf, MD
Brian Gilberti, MD

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Show Notes

Table of Contents

00:37 – Overview of Smoke Inhalation Injury

00:55 – Three Key Pathophysiologic Processes

01:41 – Physical Exam Findings to Watch For

02:12 – Airway Management and Early Intervention

03:23 – Carbon Monoxide Toxicity

04:24 – Workup and Initial Treatment of CO Poisoning

06:14 – Cyanide Toxicity

07:19 – Treatment Options for Cyanide Poisoning

09:12 – Take-Home Points and Clinical Pearls


Physiological Effects of Smoke Inhalation:

  • Thermal Injury:
    • Direct upper airway damage from heated air or steam.
    • Leads to swelling, inflammation, and possible airway obstruction.
  • Chemical Irritation:
    • Causes bronchospasm, mucus plugging, and inflammation in the lower airways.
    • Increases capillary permeability, potentially causing pulmonary edema.
  • Systemic Toxicity:
    • Primarily involves carbon monoxide and cyanide poisoning.
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