Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
Welcome to New Frontiers in Functional Medicine, Longevity & Epigenetics™ where I interview the best minds in functional medicine to discuss the science and research behind medicine, longevity, epigenetics, and so much more. Expect thought-provoking ideas, new research, lots of clinical pearls for practitioners, and step-change information for clinicians and patients. Join us! ~DrKF Copyright © 2023 by KF Education and Consulting, LLC All Rights Reserved
Episodes
September 3, 2025 • 55 mins
Can functional medicine unlock the secrets to healthy aging? In this special preview of the Functional Medicine is Longevity Medicine™ Masterclass happening on September 17- September 19, 2025, Dr. Kara Fitzgerald sits down with three leading voices in medicine and research:
- Dr. Bob Rountree: functional medicine pioneer in integrative approaches to health
- Dr. Dale Bredesen: internationally recognized expert on Alzheimer’s pre...
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August 17, 2025 • 82 mins
It was a pleasure to sit down with Dr. Nir Barzilai for a conversation that turned out to be both lively and thought-provoking. His decades of research on centenarians, biological age, and the hallmarks of aging have shaped how we think about longevity—and what’s possible when we start targeting aging itself, not just individual diseases.
We get into the science behind why some people live 20–30 years longer and healthier, and wha...
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August 4, 2025 • 53 mins
I’ve been watching the science behind Calocurb evolve over the last year, and I have to say—this is one of the most exciting clinical tools I’ve seen emerge in the metabolic space in quite some time. A hops-derived compound that stimulates endogenous GLP-1, CCK, and PYY—without a prescription or injection? That’s a big deal, especially for patients struggling with appetite regulation, weight plateaus, or the aftermath of GLP-1 disc...
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July 22, 2025 • 77 mins
In this very special episode, I have the privilege of turning the tables on Dr. Kara Fitzgerald as we celebrate 10 years of the New Frontiers podcast. I’ve been honored to walk alongside Kara on much of this journey—as a colleague, a collaborator, a mentee, and a friend—and it’s been incredible to witness the evolution of both her work and the field itself.
Together, we reflect on the stories, science, and people who have shaped t...
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July 7, 2025 • 47 mins
This is a really exciting conversation with Dr. Davide D’Amico from Timeline, where we’re taking a closer look at Urolithin A and heart health. It should come as no surprise that this mitochondrial wonderkin of a nutrient is showing promise here—especially when you consider that 40% of the heart’s weight is mitochondria. That’s an extraordinary factoid, and one that really shifts how we think about aging in the cardiovascular syste...
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June 22, 2025 • 71 mins
This episode is a little different from what we usually cover on New Frontiers, but it’s one I couldn’t wait to bring to you. I’ve been thinking a lot about how we—as clinicians—are supposed to keep up in this era of high-throughput technology. We’re swimming in data: labs, multi-omics, diet logs… and an ever-growing stream from wearables. There’s just so much coming at us, and too often, we’re awash in a sea of information without...
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June 8, 2025 • 60 mins
In many ways, the legal side of functional medicine can feel like the Wild West—uncertain, unregulated, and full of risks. The reality is, we all want to have our practices legally buttoned up, but navigating the legal landscape can feel overwhelming—and expensive. What Scott Rattigan, creator of Functional Lawyer, shares in this episode is a real game-changer. He not only breaks down the complexities of the legal side of things bu...
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May 18, 2025 • 71 mins
I’ve been looking forward to sharing this conversation with you because it’s one I’m truly passionate about. Today, we’re diving into the DunedinPACE epigenetic clock with one of its creators, the brilliant Dan Belsky. It’s a tool I use regularly with my patients, and one that’s transforming how we approach aging and interventions. While this show is a bit more technical than usual, the science is fascinating, and the real-world ap...
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May 4, 2025 • 66 mins
What if a human trial of over 1200 patients showed improved mobility and reduced pain in osteoarthritis (OA) patients using a natural combination of boswellia and celery seed extract? What if a second follow-up randomized, placebo-controlled human trial found that within 90 days, this same combination increased OA patients' ability to perform a walk test by over 50%, reduced markers of cartilage degeneration by half and increased m...
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April 19, 2025 • 66 mins
We’ve all had patients struggling with chronic conditions like long COVID, fibromyalgia, Lyme disease, and chronic fatigue. Despite all the tools in our functional medicine toolkit, there’s still something missing. How can we truly help them? I’m excited to have Ashok Gupta back on the New Frontiers podcast to offer a new take on healing from chronic illness. He explains that many chronic diseases stem from a malfunction in the br...
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April 7, 2025 • 72 mins
What if the key to reversing chronic disease, slowing cognitive decline, and boosting energy lies in the tiny powerhouses inside your cells—and we’ve finally found a way to protect them?
We know mitochondria power our cells, but did you know they also create oxidative stress as they generate energy? Protecting mitochondrial health is critical—but most antioxidants can't reach inside the mitochondria where protection is needed most...
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March 18, 2025 • 67 mins
Join me for a fascinating conversation around an exciting breakthrough in dementia detection that’s offering real hope for early intervention. Dr. Hans Frykman, Chief Scientific Officer at Neurocode Laboratories, is here to share groundbreaking insights into cutting-edge biomarkers that can identify pathology associated with Alzheimer's disease before symptoms even appear. What’s even more fascinating is how these same tools are re...
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March 10, 2025 • 61 mins
We’re witnessing an exciting shift in how we understand gut health and disease—and it’s all thanks to the powerful metabolites produced by the microbiome, like short-chain fatty acids (SCFAs) and secondary bile acids. In today’s episode, Dr. Tom Fabian shares groundbreaking insights into how these postbiotics influence intestinal barrier integrity, immune balance, and even muscle regeneration. These compounds are also connected to ...
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February 19, 2025 • 69 mins
It’s very difficult (often impossible) to completely avoid many of the environmental toxins that can cause harm - like air pollution and forever chemicals that contaminate our water and food supply. But Drs. Bob and Rosalind Wright at Mount Sinai have a hopeful solution to this dilemma. They are pioneering the study of “resiliency factors,” not just “risk factors,” that can offset the risks of harmful exposures. It’s a fresh and w...
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February 9, 2025 • 54 mins
Join me and Dr. Colleen Cutcliffe, my brilliant friend, scientist, and the powerhouse CEO of Pendulum, for our deepest dive yet into all things Akkermansia. This free-flowing conversation will take your understanding of this extraordinary strain to a whole new level. We’ll explore Akkermansia’s pivotal role in metabolic health—think cravings, weight regulation, A1C—and why we’re deficient in the first place. Plus, we’ll discuss its...
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January 12, 2025 • 71 mins
For many struggling with depression, the message they often hear from traditional care is "just live with it" or "there’s nothing more we can do." In today’s episode, we’re challenging that narrative. I’m joined by Dr. Achina Stein and Silvia Covelli from the Healing Depression Project - a groundbreaking residential treatment and research program. Dr. Stein, a functional psychiatrist, and Silvia, who’s personally battled chronic de...
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January 7, 2025 • 56 mins
We’re doing a deep dive into NAD, a molecule that has received a lot of attention but still confuses many of us, clinicians included. My guest today is able to unpack the complexities of NAD in a way you’ll find extremely illuminating and useful. I’m excited to have Dr. Greg Kelly Senior Director of Product Development at Qualia, back with us, explaining how NAD is foundational for energy, longevity, and overall cellular health. Dr...
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December 5, 2024 • 18 mins
After my conversation with Dr. Greg Fahy in August, I realized that I had additional questions that we didn't have time to address the first time around. Importantly, since here I am studying the effects of dietary and lifestyle interventions on aging, I wanted to know his thoughts on the dietary components of the TRIMM study and beyond. Dr. Fahy shares his thoughts on my question and some others on side effects on different medica...
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November 24, 2024 • 84 mins
The brain’s ability to recover after trauma is astonishing—and often overlooked in conventional care. In this episode of New Frontiers in Functional Medicine, I sit down with Dr. David Musnick, a long-time friend and brilliant clinician, to explore how we can unlock the brain’s full potential for healing. Dr. Musnick challenges the standard of care for traumatic brain injuries and post-concussion syndrome, introducing a functional ...
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November 18, 2024 • 65 mins
For anyone who has been paying attention, you may already know that the takeaways related to hormone replacement therapy (HRT) from the original Women’s Health Initiative (WHI) study have been completely overhauled. It’s about time! As a result, it’s not an understatement to say that we are in the midst of a total transformation in hormone replacement therapy (HRT) and it’s essential that as providers we (1) get up to speed on the ...
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