Evolving Past Alzheimer's

Evolving Past Alzheimer's

We are absolutely convinced that Alzheimer’s and other brain diseases are generally treatable and reversible. Early translational evidence supports this belief. The Evolving Past Alzheimer’s podcast brings you the highest caliber information about what you can do to identify, prevent, and treat Alzheimer’s disease. The show’s secondary goal is to use Alzheimer’s and cognition as a platform to explore consciousness and the human experience in it’s “second half of life.” Topics include emerging technologies, transhumanism, traditional medicinal approaches, spiritual conversations, and stories of people living with – and through – Alzheimer’s. This show brings you conversations with experts around the world that are leading the charge in treatment and prevention of Alzheimer’s and other brain disease.

Episodes

November 4, 2022 11 mins

What if what we thought to be the primary cause ofAlzheimer'swas not true? Dr. NateBergman delves into a research article published by Dr. Weaver to assess if the primary cause of Alzheimer's can be limited to only the amyloid area.

For years it has been believed that the main causes of Alzheimer’s disease are the abnormal build-up of proteins in and around the brain cells. The main toxic protein involved in this is called the amyl...

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In This Episode You Will Learn:

Where are you in your career right now? 

Neuroscience research is fascinating. Dr. Ted is most interested in attention, perception, and memory. These three things work together harmoniously because you can’t remember something you ignore...

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6 Effective Ways of Heart Disease Prevention

Anyone who wishes to optimize health by protecting the heart and brain must listen to this!

Dr. Marwan Sabbagh and Joe Piscatella combine the six most effective principles for heart disease prevention. They unfold valuable heart and brain facts in their new book Strong Heart, Sharp Mind, which are equally beneficial for the prevention of Alzheimer's ...

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The conversation had on this episode is a little complex but is an excellent review in how science is done and "how the sausage is made" in terms of medical evidence in peer review for Alzheimer's treatments.

 

We discuss the results of the AMBAR trial - The Alzheimer Management by Albumin Replacement - where people with mild to moderate Alzheimer's showed significant improvements after having their blood plasma exchanged in addit...

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In July 2021, the journal Frontiers in Neurology reported on "groundbreaking research" out of Tulane pointing to the relationship between Lyme disease and Alzheimer’s dementia. 

But since the 1980s our guest on this episode, Dr. Alan MacDonald, was stirring up the scientific debate by publishing and presenting data from his pathology laboratory that the bacteria - Borrelia Burgdorferi  often synonymous with what's called Lyme disea...

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This is a more theoretical episode that gives us some idea about what might be happening with the rhythms of an Alzheimer's or POST-COVID brain.  Our guest, Dr Thom Cleland, is a professor of theoretical and systems neuroscience at Cornell University.  His research is particularly focused on the mammalian olfactory system and on the emergent dynamical networks that govern communication and information transfer among brain areas.   ...

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In this episode, we go deep into the potential benefits of specialized meditation for our immune systems, brain-related proteins, Alzheimer's, cellular energy, and much more. Our guest, Dr Hemal Patel - is a full professor and serves as the Vice-Chair for Research in the Department of Anesthesiology at the University of California, San Diego.

If you are skeptical about meditation I urge you to check out this episode so that you

Cli...

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Earlier this year, podcast episode #65 - we spoke to Lisa and her daughters Stacy and Natalie. They told us about how they were Living Well with Alzheimer's and improving using lifestyle and personalized approach. Her cognitive decline had stabilized and seen small, but significant improvements in brain function.  This episode we review some of the elements  that have led to their success:

1) Hiring a personal assistant for Lisa as...

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“We’re actually able to change the brain, even in the face of things like Alzheimer’s disease.” This was the statement made by our guest for this show, Dr. Ben Hampstead. Dr. Hampstead is a professor at the Univ of Michigan and leads a lab that is doing several studies using transcranial direct current stimulation for mild cognitive impairment, Alzheimer's, and other forms of cognitive impairment.  We talk about his work and compar...

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November 1, 2021 32 mins

Halloween is here and the other holidays are just around the corner, so we need to discuss sugar. I share about a conversation I had with Dr. Dale Bredesen about the importance of eating right when trying to prevent cognitive impairment. It has been a long time where food and wellness was not included in the treatment plan for patients with Alzheimer’s and Dementia, but it’s such a crucial part of preventing and slowing the progres...

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Untreated and unresolved trauma is now considered to be a risk factor and contributor to Alzheimer's dementia. 

 

Trauma can be defined as any event that alters how we process, react to, and recall memories, by overwhelming the individual’s central nervous system. Additionally, trauma is defined as any event in which a person feels helpless and unsafe. It is not only an occurrence that happened in the past; instead, trauma is an ev...

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Dr. Nate Bergman quickly summarizes the story up the FDA's recent "accelerated approval" of Biogen's - Aducanumab (brand named, Aduhelm). He ends off with surprise about why he is excited about the approval...and it's probably not what you think! A quick, but useful listen.

 

In this episode we talk about…

  • The terms of the approval of the drug
  • What Aducanumab was able to accomplish in Alzheimer's patients
  • The circumstances tha...
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In this episode, we talk with Lisa, a woman in her early 70s living with Alzheimer's.  Lisa is a patient of Dr. Bergman at Kemper Cognitive Wellness.  Lisa is joined in this conversation by her daughters, Stacy and Natalie.   We discuss the successes and challenges they have had as a family living with Alzheimer's disease.  Lisa shares her thoughts about being diagnosed as well as the hope and results they have had since starting o...

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In this episode, we hear the argument in favor of the new Alzheimer's drug, Aducanumab (Aduhelm).  Dr. Marwan Sabbagh is a clinical and research leader at the Cleveland Clinic's Lou Ruvo Center for Brain Health. He was a doctor that saw patients in one of the trials that led to the FDA's Accelerated (provisional) Approval. 

Note: Dr. Sabbagh notes his disclosure as an advisor to Biogen, the maker of Aducanumab.

We discuss what Dr. ...

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This week we will do almost a Part 2 from the last episode with Drs Dale Bredesen and Kat Toups.  In that episode, we featured recently released results data on MedArchive from a clinical trial in which 84% of 25 patients with early Alzheimer's Disease and Mild Cognitive Impairment improved with a Precision Medicine approach.  

With that in mind, we want to get another perspective from the other 2 physicians who led this ground-bre...

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Our guests today are Drs Kat Toups & Dale Bredesen.

Link to the study results just released online:

https://www.medrxiv.org/content/10.1101/2021.05.10.21256982v1.full.pdf

 

Important to note, this has not yet been peer-reviewed yet.

25 participants in this group, underwent a 9-month trial.

21 people improved, 1 person no real changes and 3 people got worse to some degree.

 

2:32 - what is MedArchive and have these study results be...

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Deborah Kan is a former executive producer with the Wall Street Journal. In 2017 she founded the website BeingPatient.com, a comprehensive website dedicated to Alzheimer's news, stories, and support.

This interview covers how Deborah sees the current world of Alzheimer's research and trends in brain health and wellness.

 

5:42 - Being Patient and how it serves people who are taking care of loved ones with Alzheimer’s 

8:35 - Early ...

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This is a really unique and important episode. We are witnessing a sea change in dementia. More people are being diagnosed, earlier and younger. And people are figuring out how to actually fight back against the disease and taking ownership of their condition. My guest this week on the Evolving Past Alzheimer's podcast, Chrissy Thelker, was diagnosed with Vascular dementia at age 57 and nearly 5 years later is still living on her o...

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Some listeners have requested more personal stories of people improving and how they are doing it.  In this episode, we want to introduce you to an amazing couple, Betsy and George Muller.  George suffered a major brain injury as a result of his heart stopping about 4 years ago.  Fortunately, he has successfully recovered from the brain injury and this is the story of how the Mullers did it!

If you're interested in more details of ...

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We get many questions from listeners and people seeking Alzheimer’s prevention and early intervention about the risks and benefits of hormone therapies, such as estrogen and progesterone.

Our guest this episode, Felice Gersh MD and co-authors recently published an article entitled:

Postmenopausal hormone therapy for cardiovascular health: the evolving data

 

In this episode we talk about:

  • Hormone Therapy in this episode is re...
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