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July 11, 2025 58 mins
Dr. Reedy welcomes Dr. Alexa Altman where she discusses how psychedelics bring the unconscious material into consciousness. She talks about the importance of integration. Dr. Altman’s Website: https://www.i-psychedelic.com 1. Single-dose psilocybin (25 mg) with psychological support for MDDJAMA – “Single-Dose Psilocybin Treatment for Major Depressive Disorder” psychiatryonline.org+15sunstonetherapies.com+15pmc.ncbi.nlm.nih.gov+15 Summary: Demonstrated strong antidepressant effects and good tolerability over follow-up. Email: info@hopkinspsychedelic.org 2. One-Year Follow-Up of Psilocybin for DepressionStudy: Long-term effects of psilocybin therapy for depressionJohns Hopkins – “Psilocybin treatment for major depression effective for up to a year” Summary: 67% of participants remained in remission one year post-treatment.3. MDMA-Assisted Therapy for Severe PTSDRandomized, placebo-controlled MDMA-assisted therapyNature Medicine – “MDMA-assisted therapy for severe PTSD” Summary: Significant reduction in PTSD symptoms, well‑tolerated in a diverse cohort.Contact (MAPS / Lykos Therapeutics): Email: info@maps.org 4. Psilocybin for Cancer-Related Anxiety & DepressionPsilocybin in patients with life-threatening cancerPMC – “High-dose psilocybin produced large decreases in depressed mood and anxiety…” Summary: 80% of participants maintained significant symptom relief at 6 months. Website: heffter.org (contact via site) en.wikipedia.org 1. Johns Hopkins UniversityCenter for Psychedelic and Consciousness ResearchPsilocybin for depression, anxiety, addiction, and end-of-life distressWhy it’s top-tier: The first major U.S. institution to receive regulatory approval for psychedelic research in modern times. 🔗 hopkinspsychedelic.org 2. Imperial College LondonCentre for Psychedelic ResearchPsilocybin for treatment-resistant depression, brain imaging, DMT studiesWhy it’s top-tier: Home of pioneering neuroimaging studies on psychedelics; led by Robin Carhart-Harris (now at UCSF). 🔗 imperial.ac.uk 3. Multidisciplinary Association for Psychedelic Studies (MAPS)MDMA for PTSD (now in Phase 3 trials), harm reduction, global educationWhy it’s top-tier: MAPS initiated the first FDA-approved Phase 3 trials for MDMA-assisted therapy. 🔗 maps.org4. University of California, San Francisco Psychedelic Research Program Psilocybin, DMT, ibogaine; Robin Carhart-Harris now leads U.S. armWhy it’s top-tier: Integrates neuroscience, clinical psychology, and pharmacology. 🔗 psychedelics.ucsf.edu5. NYU Langone HealthCenter for Psychedelic MedicineEnd-of-life anxiety, alcoholism, PTSD, and psilocybin studiesWhy it’s top-tier: Known for rigorous clinical trials and major collaborations. 🔗 med.nyu.edu6. University of California, Los AngelesUCLA Psychedelic Studies InitiativePsilocybin + CBT, anxiety, clinical protocolsWhy it’s top-tier: Conducting one of the few FDA-regulated psilocybin trials with integrated therapy. 🔗 uclapsi.org7. University of Wisconsin–Madison / Usona InstitutePsilocybin for major depression (FDA Phase 3 trials)Why it’s top-tier: Leading U.S.-based nonprofit with regulatory traction and major academic partnerships. 🔗 usonainstitute.org8. Massachusetts General Hospital / Harvard Medical SchoolCenter for the Neuroscience of PsychedelicsNeurobiological mechanisms of psychedelicsWhy it’s top-tier: Combines Harvard academic leadership with Mass General clinical infrastructure. 🔗 massgeneral.org9. University of New MexicoPsychedelic-Assisted Therapies & Research GroupKetamine, DMT, and MDMA research; Indigenous-informed approachesWhy it’s top-tier: Interdisciplinary and trauma-informed program with cultural awareness. 🔗 hsc.unm.edu10. Oregon Health & Science University State-licensed psilocybin therapy programs, public health, trainingWhy it’s top-tier: One of the first institutions engaging with psilocybin therapy post-legalization under Measure 109. 🔗 ohsu.edu

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