Freely Filtered, a NephJC Podcast

Freely Filtered, a NephJC Podcast

Twice monthly (aspirational) recap of the NephJC journal club. NephJC reviews the most important manuscripts which are driving nephrology forward and improving our understanding of the kidney.

Episodes

December 14, 2025 80 mins

The Filtrate

Joel Topf‍ ‍@kidneyboy.bsky.social‬ (COI)

Swapnil Hiremath @hswapnil.medsky.social and on LinkedIn

Pedro Teixeira @nephcrit.bsky.social

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The Filtrate

Joel Topf‍ ‍@kidneyboy.bsky.social‬ (COI)

Sophia Ambruso @sophia-kidney.bsky.social

Swapnil Hiremath @hswapnil.medsky.social and on LinkedIn

<...

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November 17, 2025 49 mins

The Filtrate

Joel Topf‍ ‍@kidneyboy.bsky.social‬

Sophia Ambruso @sophia-kidney.bsky.social

Nayan Arora @captainchloride.bsky.social

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The Filtrate

Joel Topf @kidneyboy.bsky.social‬

Swapnil Hiremath @hswapnil.medsky.social

Nayan Arora captainchloride.bsky.social

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The Filtrate

Joel Topf Bluesky: @kidneyboy.bsky.social‬

Jordy Cohen Bluesky: @jordybc.bsky.social‬

Swapnil Hiremath Bluesky: @hswapnil.medsky.social‬

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May 12, 2025 78 mins

The Filtrate

Joel Topf

AC Gomez

Sophia Ambruso

Nayan Arora

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The Filtered Fragments (OG Filtrate)

Joel Topf

Jennie Lin

Swapnil Hiremath

Special Guest

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March 12, 2025 68 mins

The Filtrate

Joel Topf

Jordy Cohen

Nayan Arora

Special Guest

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February 26, 2025 72 mins

The Filtrate

Joel Topf

Swapnil Hiremath

AC Gomez

Sopia Ambruso

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December 15, 2024 90 mins

The Filtrate

Joel Topf

Swapnil Hiremath

AC Gomez

Jordy Cohen

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The Filtrate:

Joel Topf

Swapnil Hiremath

With Special Guest:

Michelle Hladunewich, Nephrologist at the University of Toronto

Mir Melamed, Maternal-Fetal Medicine at the University of Toronto

Editor

Simon Topf

Show Notes

Priscilla Smith’s letter:

Dear Joel and the Freely Filtered team,

I am a long-time fan of your podcast and was looking forward to hearing your recently aired discussion of the Praecis study of sflt1:PlGF use in preeclampsia. ...

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November 4, 2024 137 mins

We had a great NephJC get together. We recorded the whole event and packaged it into a podcast.

Musical entertainment

Tim Yau (@Maximal_Change)

Too Sweet by Hozier

Fairy Tale of New York by written Jem Finer and Shane MacGowan. Hear it performed by the Pogues.

Interview of Tom Mueller

Tom Mueller author of How to Make a Killing

Jade Teakall@jmteakell

Graham Abra@GrahamAbra

Interview of Tom Mueller

Tom Mueller author of How to Make a Killing

J...

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October 18, 2024 92 mins

The Filtrate:

Jennie Lin

Joel Topf

Josh Waitzman

Swapnil Hiremath

With Special Guests

Pedro Teixeira

Jay Koyner

Editor

Sophia Ambruso

Show Notes

The article: A Randomized Trial of Intravenous Amino Acids for Kidney Protection

NephJC Summary

KDIGO Clinical Practice Guideline for Acute Kidney Injury (PDF)

Steve Coca study Evaluation of Short-Term Changes in Serum Creatinine Level as a Meaningful End Point in Randomized Clinical Trials (PubMed)

Usi...

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The draft order:

Sophia Ambruso

Nayan Arora

Swapnil Hiremath

AC Gomez

Joel Topf

Editor

Nayan Arora

Show Notes

Previous drafts:

2021 KDIGO Hypertension —Joel, Sophia, Swap, Nayan, Josh

2021 ASN Kidney Week Draft—Joel, Sophia, Swap, Nayan, Jennie

2022 The ISPD Peritonitis Guideline— Joel, Sophia, Swap, Nayan

2022 ASN Kidney Week Draft—Joel, Sophia, Swap, Nayan

2023 ASN Kidney Week Draft—Joel, Sophia, Swap, Nayan, AC, Josh

2024 KDIGO CKD Clinical P...

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The Filtrate:

Joel Topf

Josh Waitzman

With Special Guest:

Brad Rovin (@BradRovin) Chief of nephrology at The Ohio State University Wexner Medical Center, one of the authors of the Nefigard trial.

Koyal Jain (@koyaljainMD) Program director of the GN Fellowship at University of North Carolina

Roger Rodby (@NephRodby) Associate program director of the Rush University Nephrology Fellowship

Editor

Sophia Ambruso

Show Notes

The manuscript (The ...

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June 1, 2024 83 mins

The Filtrate:

Joel Topf

Swapnil Hiremath

Josh Waitzman

Nayan Arora

Sophia Ambruso

With Special Guest:

Brendon Neuen Super smart guy and clinical trialist

Vlado Perkovic Lead author of FLOW and friend of NephJC

Editor

Joel Topf

Show Notes

The manuscript (NEJM): Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes

The acronym FLOW from the title: evaluate renal Function with semagLutide Once Weekly (Twitter)

Joel wrot...

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The Filtrate:

Joel Topf

Swapnil Hiremath

AC Gomez

Nayan Arora

With Special Guest:

Anuja Java, complement god and pre-eclampsia research (Twitter)

Shannon M. Clark, MD, FACOG, an honest to god, true, maternal-fetal medicine specialist. (Website | Instagram)

Editor

Nayan Arora

Show Notes

CHIP Study from 2015 (NEJM | NephMadness 2015)

CHAP study from 2022 (NEJM | NephJC)

NephMadness 2024 coverage of the diagnosis of preeclampsia

sFlt background:...

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The Filtrate:

Joel Topf

Swapnil Hiremath

Priya Yenebere

Nayan Arora

With Special Guest:

Brendon Neuen Super smart guy and clinical trialist

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