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June 8, 2025 27 mins
Preparation for a colonoscopy is not a pleasant or positive experience. From laxatives to the invasiveness and sedation involved, preparing for a colonoscopy is something most patients dread and try to avoid. Fortunately, clinicians and patients can look forward to colonoscopy and colon cancer screening modalities that require no preparation. Today’s guest is Alex Ovadia, CEO of Check-Cap. The company is developing a capsule called, C-Scan, for colon cancer screening, and a U.S. clinical trial has begun. Some of the highlights of the show include: ● Alex describes the motivation behind Check-Cap’s capsule and meeting a need for no-prep to detect polyps from inside the body. ● Check-Cap’s capsule avoids sedation and insertion of a colonoscope in the patient’s body. ● Check-Cap’s capsule modality is simply “swallow and forget.” The capsule uses an algorithm that runs scanning throughout the colon. ● There’s a lot of room for error for patients who have a colonoscopy. Decision intelligence is being developed to prevent human errors that impact patients. ● Alex shares Check-Cap’s current stage of commercialization and upcoming milestones for its capsule. IRB approval has been received. ● Each year, about 880,000 deaths worldwide are due to colon cancer. Check-Cap’s capsule strives to make sure people have better and healthier lives. ● Quality is critical when it comes to the progression of commercializing. Alex describes efforts to maintain safety and compliance with Check-Cap’s capsule.
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