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July 15, 2025 79 mins
Today, Dr. Lovely welcomes a conversation with Amitay Eshel, co-founder and CEO of Young Goose and host of the Biohacking Beauty podcast. Amitay, an entrepreneur in the biohacking and beauty industries, explains the science behind accelerated skin aging during perimenopause and menopause, focusing on how declining estrogen impacts essential skin components like collagen, elasticity, hyaluronic acid, and cellular autophagy.
 
Highlights from our chat:
  • NAD+ is a foundational molecule for cellular repair and longevity, whose levels decline rapidly with age and are further reduced by falling estrogen, leaving skin "starved".
  • Amitay focuses on an "upstream" method of anti aging with the skin, providing NAD+ precursors like NMN to replenish energy and repair functions, rather than just treating visible wrinkles.
  • Spermadine is introduced as a "magical molecule" essential for triggering autophagy, the body's vital cellular recycling process that renews older cells and boosts collagen production.
  • Women experience accelerated skin aging during perimenopause and menopause due to significant drops in estrogen, leading to rapid declines in collagen, elasticity, hyaluronic acid, and autophagy, contributing to a pro-inflammatory skin state.
  • Young Goose integrates these NAD+ innovations and spermadine into its skincare range, offering a holistic approach to biological aging in the skin.
Find out more about Young Goose skincare and Amitay by visiting younggoose.com (code LOVELY for a 10% discount).  Find the 2 products Dr. Lovely speaks about in the show here:  Hyperbaric Mask and the Eye C.A.R.E.  (don't forget to use the code LOVELY) !! 🥰
 
More information is also available on the Biohacking Beauty podcast and their Instagram page, @young_goose_skincare.
 

Thank you to our sponsors for this episode:

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