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March 7, 2025 55 mins
After reviewing over 100,000 lab values, 5000 biomarkers and epigenetics, he explored which biomarkers were predictive of optimal health and longevity..  He also has recommendations on how to improve each of these markers which improves and individual's health trajectory.  These biomarkers are:
Hemoglobin A 1 C (HbA1c) should be less than 5 %
  • This is a measure of glycation (sugar stuck to hemoglobin) within the body within the body.
  • Fructosamine is a back up measure if red blood cells are destroyed quickly (e.g. By immune conditions)
  • If it is less than 5, you have a 99 % chance of living ten more years
     
HsCRP. High sensitivity C reactive protein should be less than .5
  • This is a measure of inflammation
Homocysteine should be less than 6
  • An all mortality marker
  • This has a high correlation with all chronic diseases and is affected by methlation which is improved with folate and B vitamins
Vitamin D levels
  • This is correlated with the risks for chronic diseases including covid
8 oxy guanine a test of DNA damage and oxidative damage (less than 5)
 
Omega 3 index should be greater than 8
 
Digestive Transit time should be less than 18 to 24 hours
  • This measures time from eating food til it reaches the toilet.  If this is too long, toxic components can be reabsorbed.  If it is too short, nutrients may not be absorbed.  It can be measured by taking charcoal and measuring the time until it reaches the toilet
Morning Urine PH should be between 6.5 and 7.5
  • A measure of the body's alkalinity/ acidity

Russell Jaffe, MD, PhD, CCN
Dr. Russell Jaffe received his BS, MD and PhD from the Boston University School of Medicine i1972. He completed residency training in clinical chemistry at the National Institutes of Health
(1973 – 1976), remaining on the permanent senior staff until 1979. He is board certified in Clinical Pathology and in Chemical Pathology.  As a physician and scientist who aspired to be comprehensive, objective, empiric and experiential, Dr. Jaffe started his career searching for deeper understanding, wisdom, evidence and insight in mechanisms of health. Through intense curiosity and learned skepticism, Dr. Jaffe sought to debunk the best-known advocates of a variety of health promotion and healing systems. What started as a journey to disprove holistic forms of care became a rich educational experience that transformed Dr. Jaffe into a student and then researcher in such areas a Traditional Chinese Medicine, acupuncture, active meditation, homeopathy, and manipulative arts.
 
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