Oxford Sparks Big Questions

Oxford Sparks Big Questions

'Will my bacon sandwich kill me?', 'Is vaping better than smoking?', 'How do you become an astronaut?' - just some of the Big Questions we ask some of the brightest minds behind Oxford science. Join us in each podcast as we explore a different area of science.

Episodes

June 25, 2025 14 mins

What's the best gift you can give? To the millions of people whose lives have been saved by complete strangers, the answer would be simple: blood. But what exactly happens when blood has been donated, and how do we know it is safe? We chat to Dr Richard Mayne from Oxford's Experimental Medicine Division about genomics, Next-Generation Sequencing, blood screening (...and Star Trek). 

Could you be a blood-donating hero? Blood stocks ...

Mark as Played

Whether you've been served an advert for it, or just heard about it in the media, it's likely that 'Ozempic' isn't a totally unfamiliar word. Now often associated with weight-loss, Ozempic is actually the brand name for a drug used to treat diabetes. So what exactly is it, how does it work, and is it safe? We chat to diabetes and endocrinology (hormone) expert Dr Annie de Bray to find out.

 

Mark as Played

We've all been there...you're on the train, maybe tired after a long day, and all you can hear is one side of a fellow passenger's not-too-interesting phone conversation. Or worse, their choice of music, made tinny and monotonous by the awkward angle of their phone speaker. It's irritating, sure, but for some people it goes beyond mild annoyance, into the realms of anger and panic. For these people - who suffer from a condition cal...

Mark as Played
May 14, 2025 14 mins

With more than 70% of its surface covered in water, Earth is rightly known as the "blue planet". But where did this water - so essential to life - originate? While some theories suggest that hydrogen was delivered to Earth from space via asteroids, new research indicates that the building blocks for water may have been present on our planet all along. We chat to Tom Barrett from Oxford's Department of Earth Sciences to find out mor...

Mark as Played

What do you do when the subject of your research lies deep beneath the waves? Send down an underwater robot, of course! We chat to volcanologist Sofia Della Sala about her recent fieldwork expedition to Santorini, where she used a Remotely Operated Vehicle, or ROV, to search for hydrothermal vents in the Aegean Sea. These vents - which are like hot springs on the sea floor - could provide vital insight into the volcanic and tectoni...

Mark as Played
April 16, 2025 15 mins

"I still don't believe it happened..."

What's it like to face the most famous clock on television? We chat to Oxford mathematician Dr Tom Crawford - best known as the creator of the award-winning 'Tom Rocks Maths' outreach programme - about what it was like to step into Rachel Riley's shoes on Countdown

What's the best tactic for tackling the numbers round? How did he prepare? Did he really only have 30 seconds to find a solution...

Mark as Played

One in two people will be affected by dementia in their lifetime - whether that is as a patient, or somebody caring for a loved one. But what happens after a dementia diagnosis? Is there a clear pathway ahead? We chat to Jasmine Blane, a DPhil researcher at the Oxford Brain Health Clinic, about the work she is doing to help support patients in the midst of a dementia diagnosis, and into the future.

Mark as Played
March 19, 2025 15 mins

In popular culture, Tourette's syndrome is wrongly associated solely with outbursts of swearing in the context of lazy jokes. But in reality, the condition is far more complex than this stereotype suggests. When people without Tourette’s jokingly blame their lack of self-control on the condition, it spreads misinformation and invalidates those who actually live with it. Despite this, ...

Mark as Played
March 5, 2025 13 mins

If you were hunting for some fossilised dinosaur footprints, where would you go? To a remote part of North or South America, perhaps? A deserted wilderness for sure... But how about Oxfordshire? We chat to Dr Duncan Murdock from the Oxford University Museum of Natural History about an incredible discovery made right on our doorstep.

Photo © Dr Emma Nicholls / Oxford University Museum of Natu...

Mark as Played
February 19, 2025 15 mins

Shh...hedgehog! It always feels like a privilege to catch a glimpse of one, as it snuffles away under the garden fence. And come the spring, our spiny - and usually solitary - little friends will be feeling in the mood for...romance. But what exactly does a female look for in a mate? And how do their intimate encounters even work when things are so very... spiky? Join us for this special Valentine's Day edition of the Big Questions...

Mark as Played

Electric eels are pretty amazing creatures. Their bodies can release powerful electric charges - in some cases reaching 650 volts! So, what can scientists learn from these animals? Could nature hold the key to advancing our own energy solutions? We chat to Dr Yujia Zhang about how electric eels might inspire the batteries of the future.

Mark as Played

Whether it's the bottle of water that you hastily grab at the train station, or your favourite guilty-pleasure fizzy pop, you may have noticed something different about your drinks lately - or at least their containers. Since July 2024, it's been EU law that bottle caps are attached, or 'tethered', on all single-use plastic bottles. But what exactly is the reason for this change? Will it really help to save the planet, or is it jus...

Mark as Played

Even if you’d never previously given much thought to the Northern Lights, chances are they were brought to your attention in 2024, when our social media feeds were set ablaze with beautiful images captured by awe-struck stargazers. Usually restricted to more northerly latitudes, this colourful natural phenomenon could be observed in the UK as far south as Cornwall. But why were we treated to this spectacle, and why now? Dr Carly Ho...

Mark as Played
December 11, 2024 13 mins

Mistletoe has long been associated with fertility, and even today, its presence hanging from the ceiling can prompt a few blushes. But, did you know, mistletoe is more than something beneath which to kiss at Christmas? It is actually a parasite, and has some rather peculiar biology behind it. We chat to mistletoe expert Ollie Spacey about what makes it so special, where you can spot it and - importantly - how you can get involved w...

Mark as Played
November 27, 2024 12 mins

Evolutionarily speaking, it makes sense to have a lot of children. At the very least, we might expect a population to replace itself, with each couple having an average of two children. However, this evolutionary logic is not mirrored by current data: birth rates are falling in the UK, with many people choosing to either have one child, or no children at all. We speak to evolutionary anthropologist Dr Paula Sheppard about the drive...

Mark as Played
November 13, 2024 12 mins

Chances are, you didn't notice the week-long wind drought that the UK experienced towards the end of 2023. However, this period of low wind speeds, combined with a cold snap, drove up our energy prices - something that may have caught your attention. So, what exactly do we know about wind droughts, and how can we apply this knowledge to plan for the low-carbon energy systems of the future? We chat to Matthew Wright from Oxford's De...

Mark as Played

Welcome back to the new series of the Oxford Sparks Big Questions Podcast! We are here to answer weird and wonderful questions about our world, with the help of science. And we’re starting with a very big question! How do you sequence the genomes of 70,000 species?

Read more

Mark as Played

Summer is here, and with heatwaves forecast, how do we keep our homes cool without relying on air conditioning?

 

Read more

Mark as Played
July 3, 2024 14 mins

Scientists are returning to the moon, but when they get there, what time is it?

Dr Carly Howett from the Department of Physics explains the basics: what time is, and how we...

Mark as Played
June 19, 2024 12 mins

Discover how the ancient art of origami is revolutionising sustainable energy!

Researcher Jingyi Yang, from the Department of Engineering Science, has loved origami since c...

Mark as Played

Popular Podcasts

    United States of Kennedy is a podcast about our cultural fascination with the Kennedy dynasty. Every week, hosts Lyra Smith and George Civeris go into one aspect of the Kennedy story.

    Stuff You Should Know

    If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

    Dateline NBC

    Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

    The Clay Travis and Buck Sexton Show

    The Clay Travis and Buck Sexton Show. Clay Travis and Buck Sexton tackle the biggest stories in news, politics and current events with intelligence and humor. From the border crisis, to the madness of cancel culture and far-left missteps, Clay and Buck guide listeners through the latest headlines and hot topics with fun and entertaining conversations and opinions.

    Crime Junkie

    Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.

Advertise With Us
Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.