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June 5, 2019 68 mins
Go online to PeerView.com/KWE860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this PeerView MasterClass, an expert panel of oncology nurse professionals presents the highlights of emerging science and clinical data on PARP inhibition in multiple solid tumors, assesses the role of companion diagnostic tests that identify patients with DDR mutations, as well as engage the audience in a stimulating discussion on the value of genetic testing and significance of enrollment in ongoing PARP inhibitor clinical trials. Going beyond the standard didactic lectures, our experts share their own perspectives on best practice strategies to effectively and safely use approved and emerging PARP inhibitors within the framework of challenging case scenarios. Upon completion of this activity, participants will be able to: Describe DNA-damage response (DDR) pathways and the rationale for targeting DDR mutations with PARP inhibitors as a cancer therapeutic strategy, Assess the clinical role, efficacy, and safety of PARP inhibitors in multiple tumor types, including ovarian, breast, pancreatic, and prostate cancers, across different treatment settings, Counsel patients receiving PARP inhibitor therapy on strategies to prevent and/or manage treatment emergent adverse events, Provide appropriate education and guidance to patients on the safe and effective clinical use of novel PARP inhibitors, including dosing, the need for adherence to therapy, and enrollment into clinical trials.
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