Practical AI
Making artificial intelligence practical, productive & accessible to everyone. Practical AI is a show in which technology professionals, business people, students, enthusiasts, and expert guests engage in lively discussions about Artificial Intelligence and related topics (Machine Learning, Deep Learning, Neural Networks, GANs, MLOps, AIOps, LLMs & more). The focus is on productive implementations and real-world scenarios that are accessible to everyone. If you want to keep up with the latest advances in AI, while keeping one foot in the real world, then this is the show for you!
Episodes
In this Fully-Connected episode, Dan and Chris start with Anthropic's Mythos frontier model, parsing what is publicly known about its cybersecurity capabilities and projecting its possible implications from "We've been here before. 🙄" to "See ya, cybersecurity! 😱" It's the end of the world as we know it, and I feel fine. 🙃
Then they have fun with the craziest AI announcement of the year (except for the Mythos one of cou...
Autonomous driving is not just a big tech or closed-source game, it's becoming accessible through open innovation and real-world deployment. Dan and Chris sit down with Harald Schäfer, CTO at Comma AI, to explore how OpenPilot is bringing self-driving to everyday vehicles using open source AI. We dive into the intersection of machine learning, robotics, and simulation, including how world models are enabling training at sc...
In this fully connected episode, Dan and Chris break down the Anthropic Claude Code leak, what went wrong and what it reveals about agentic systems, AI architecture, and AI safety. They also explore how the open source community is responding and why this moment could reshape how AI systems are built and secured.
Featuring:
Upco...
AI is rapidly transforming how software is built, shifting economic incentives from open source code and collaboration toward on-demand, personalized development through agentic coding a.k.a. vibe coding. In this episode, Chris speaks with Miklós Koren of Central European University about how AI is reshaping open source and the software industry. They explore the economics of incentives, evolving collaboration patterns, an...
What does “AI at the edge” really mean in 2026, and why does it matter now more than ever before? In this episode, we’re joined by Brandon Shibley, Edge AI Solutions Engineering Lead at Qualcomm’s Edge Impulse, to discuss the current state and future of Edge AI in 2026. We discuss Gen AI, Small Models, and Cascades of Models, along with real-world constraints like latency, power, and privacy. We also dive into the role of ...
What happens when an AI hater starts building with AI agents? In this episode, we talk with software engineer Steve Klabnik, known for his work on the Rust programming language, about his journey from criticizing AI to experimenting with it firsthand. We explore Steve’s programming language Rue, largely built with the help of AI tools like Claude, and discuss what this means for software engineering and the future of codin...
AI is reshaping global power, from chip manufacturing and computing power to AI governance and US-China relations. In this episode, Ben Buchanan, Assistant Professor at The Johns Hopkins University and former White House Special Advisor for AI, explores how AI policy, geopolitics, and international cooperation intersect with AI innovation and AI safety. We discuss the strategic importance of computing power, the future o...
As AI accelerates innovation and adoption, leaders are facing rising cognitive load, shifting systems, and new emotional realities inside their organizations. In this episode, Deloitte’s Chief Innovation Officer Deborah Golden joins us to explore how AI is reshaping leadership, why vulnerability and empathy are critical in this moment, and how anti-fragility, not just resilience, will define the future of work.
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AI is moving fast from research to real-world deployment, and when things go wrong, the consequences are no longer hypothetical. In this episode, Sean McGregor, co-founder of the AI Verification & Evaluation Research Institute and also the founder of the AI Incident Database, joins Chris and Dan to discuss AI safety, verification, evaluation, and auditing. They explore why benchmarks often fall short, what red-teaming ...
AI agents are moving from demos to real workplaces, but what actually happens when they run a company? In this episode, journalist Evan Ratliff, host of Shell Game, joins Chris to discuss his immersive journalism experiment building a real startup staffed almost entirely by AI agents. They explore how AI agents behave as coworkers, how humans react when interacting with them, and where ethical and workplace boundaries begi...
As AI increasingly shapes geopolitics, elections, and civic life, its impact on democracy is becoming impossible to ignore. In this episode, Daniel and Chris are joined by security expert Bruce Schneier to explore how AI and technology are transforming democracy, governance, and citizenship. Drawing from his book Rewiring Democracy, they explore real examples of AI in elections, legislation, courts, and public AI models, t...
As generative AI moves into production, traditional guardrails and input/output filters can prove too slow, too expensive, and/or too limited. In this episode, Alizishaan Khatri of Wrynx joins Daniel and Chris to explore a fundamentally different approach to AI safety and interpretability. They unpack the limits of today’s black-box defenses, the role of interpretability, and how model-native, runtime signals can enable sa...
In this start-of-year FC episode, Chris and Daniel break down what really mattered in AI in 2025, and what to expect in 2026. They explore the rise of AI agents, the practical reality of multimodal AI, and how reasoning models are reshaping workflows. The conversation dives into infrastructure and energy constraints, the continued value of predictive models, and why orchestration (not just better models) is becoming the de...
As AI reshapes the workplace, employees and leaders face questions about meaningful work, automation, and human impact. In this episode, Jason Beutler, CEO of RoboSource, shares how companies can rethink workflows, integrate AI in accessible ways, and empower employees without fear. The discussion covers leveraging AI to handle routine tasks (SOPs or "plays") and reimagining work for smarter, more human-centered outcomes.
F...
Chris and Daniel talk with returning guest, Ramin Mohammadi, about how those seeking to get into AI Engineer/ Data Science jobs are expected to come in a mid level engineers (not entry level). They explore this growing gap along with what should (or could) be done in academia to focus on real world skills vs. theoretical knowledge.
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Chris and Daniel unpack how AI-driven document processing has rapidly evolved well beyond traditional OCR with many technical advances that fly under the radar. They explore the progression from document structure models to language-vision models, all the way to the newest innovations like Deepseek-OCR. The discussion highlights the pros and cons of these various approaches focusing on practical implementation and usage.
Fe...
This episode is a special crossover between the Practical AI podcast and The Changelog podcast. Chris was recently invited by longtime friends Jerod Santo and Adam Stacoviak, cohosts of The Changelog, to join them on the show. They discuss AI, drones, robotics, swarming technology, and the rise of high-performance edge computing with Rust. Chris points out that open source software, small AI models, and affordable hardwar...
Fireflies CEO, Krish Ramineni shares how the company is transforming AI-powered note-taking into a deeper layer of knowledge automation. He breaks down the technology behind real-time functionality like Live Assist, the user behavior patterns driving product evolution, and how Fireflies is innovating far beyond meetings. Krish also shares insights on future trends in AI and the potential for hardware integration, emphasizi...
Waymo’s VP of Research, Drago Anguelov, joins Practical AI to explore how advances in autonomy, vision models, and large-scale testing are shaping the future of driverless technology. The conversation dives into the dual challenges of building an onboard driver and testing that driver (via large scale simulation). Drago also gives us an update on what Waymo is doing to achieve intelligent, real-time performance while ensur...
Dan and Chris unpack whether today’s surge in AI deployment across enterprise workflows, manufacturing, healthcare, and scientific research signals a lasting transformation or an overhyped bubble. Drawing parallels to the dot-com era, they explore how technology integration is reshaping industries, affecting jobs, and even influencing human cognition, ultimately asking: is this a bubble, or just a fizzy new phase of innova...
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