Practical AI
Making artificial intelligence practical, productive & accessible to everyone. Practical AI is a show in which technology professionals, business people, students, enthusiasts, and expert guests engage in lively discussions about Artificial Intelligence and related topics (Machine Learning, Deep Learning, Neural Networks, GANs, MLOps, AIOps, LLMs & more). The focus is on productive implementations and real-world scenarios that are accessible to everyone. If you want to keep up with the latest advances in AI, while keeping one foot in the real world, then this is the show for you!
Episodes
Longtime friend of the show Rajiv Shah returns to unpack lessons from a year of building retrieval-augmented generation (RAG) pipelines and reasoning models integrations. We dive into why so many AI pilots stumble, why evaluation and error analysis remain essential data science skills, and why not every enterprise challenge calls for a large language model.
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In this episode, Daniel and Chris are joined by Chris Aquino, software engineer at Thunderbird to hear the story of how they developed a privacy-preserving AI executive assistant. They discuss various design decisions including remote (but confidential) inference, local encryption, and model selection. Chris A. does an amazing job describing the journey from "let the big LLM do everything" to splitting apart the workflow t...
In this Fully Connected episode, we dig into the recent MIT report revealing that 95% of AI pilots fail before reaching production and explore what it actually takes to succeed with AI solutions. We dive into the importance of AI model integration, asking the right questions when adopting new technologies, and why simply accessing a powerful model isn’t enough. We explore the latest AI trends, from GPT-5 to open source mod...
Daniel and Chris sit with Citadel AI’s Rick Kobayashi and Kenny Song and unpack AI safety and security challenges in the generative AI era. They compare Japan’s approach to AI adoption with the US’s, and explore the implications of real-world failures in AI systems, along with strategies for AI monitoring and evaluation.
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Dan and Chris break down Winning the Race: America's AI Action Plan, issued by the White House in July 2025. Structured as three "pillars" — Accelerate AI Innovation, Build American AI Infrastructure, and Lead in International AI Diplomacy and Security — our dynamic duo unpack the plan's policy goals and its associated suggestions — while also exploring the mixed reactions it’s sparked across political lines. They connect...
Allegra Guinan of Lumiera helps leaders turn uncertainty about AI into confident, strategic leadership. In this conversation, she brings some actionable insights for navigating the hype and complexity of AI. The discussion covers challenges with implementing responsible AI practices, the growing importance of user experience and product thinking, and how leaders can focus on real-world business problems over abstract exper...
Dan sits down with guests Mark Daniel Ward and Katie Sanders from The Data Mine at Purdue University to explore how higher education is evolving to meet the demands of the AI-driven workforce. They share how their program blends interdisciplinary learning, corporate partnerships, and real-world data science projects to better prepare students across 160+ majors. From AI chatbots to agricultural forecasting, they discuss th...
We unpack how AI is reshaping hiring decisions, shifting job roles, and creating new expectations for professionals — from engineers to marketers. They explore the rise of AI-assisted teams, the growing compensation bubble, why continuous learning is now table stakes, and how some service providers are quietly riding the AI wave.
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In this episode, Chris sits down with Igor Nikitin, CEO and co-founder of Nice Technologies, to explore how AI and modern engineering practices are transforming the actuarial field and setting the stage for the future of actuarial modeling. We discuss the introduction of programming into insurance pricing workflows, and how their Python-based calc engine, AI copilots, and DevOps-inspired workflows are enabling actuaries to...
In this episode of Practical AI, Chris and Daniel explore the fascinating world of agentic AI for drone and robotic swarms, which is Chris's passion and professional focus. They unpack how autonomous vehicles (UxV), drones (UaV), and other autonomous multi-agent systems can collaborate without centralized control while exhibiting complex emergent behavior with agency and self-governance to accomplish a mission or shared go...
In the first episode of an "AI in the shadows" theme, Chris and Daniel explore the increasing concerning world of agentic misalignment. Starting out with a reminder about hallucinations and reasoning models, they break down how today’s models only mimic reasoning, which can lead to serious ethical considerations. They unpack a fascinating (and slightly terrifying) new study from Anthropic, where agentic AI models were caug...
In this episode, we sit down with Joey Conway to explore NVIDIA's open source AI, from the reasoning-focused Nemotron models built on top of Llama, to the blazing-fast Parakeet speech model. We chat about what makes open foundation models so valuable, how enterprises can think about deploying multi-model strategies, and why reasoning is becoming the key differentiator in real-world AI applications.
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Can AI-driven autonomy reduce harm, or does it risk dehumanizing decision-making? In this “AI Hot Takes & Debates” series episode, Daniel and Chris dive deep into the ethical crossroads of AI, autonomy, and military applications. They trade perspectives on ethics, precision, responsibility, and whether machines should ever be trusted with life-or-death decisions. It’s a spirited back-and-forth that tackles the big ques...
It seems like we are bombarded by news about millions of dollars pouring into AI startups, which have crazy valuations. In this episode, Chris and Dan dive deep into the highs, lows, and hard choices behind funding an AI startup. They explore early bootstrapping, the transition to venture capital, and what it’s like to trade in code commits for investor decks.
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An recent article in Variety was titled: "Sylvester Stallone-Backed Largo.ai Teams With Brilliant Pictures for ‘World’s First Fully AI-Automated Film Company’". Obviously this caught our attention! We sit down with Sami Arpa, CEO of Largo.ai, to unpack how films are developed, funded, and brought to life using AI. We discover how tools like script analysis, financial forecasting, and digital twins are helping creators and ...
Chong Shen from Flower Labs joins us to discuss what it really takes to build production-ready federated learning systems that work across data silos. We talk about the Flower framework and it's architecture (supernodes, superlinks, etc.), and what makes it both "friendly" and ready for real enterprise environments. We also explore how the generative Generative AI boom is reshaping Flower’s roadmap.
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In this first of a two part series of episodes on federated learning, we dive into the evolving world of federated learning and distributed AI frameworks with Patrick Foley from Intel. We explore how frameworks like OpenFL and Flower are enabling secure, collaborative model training across silos, especially in sensitive fields like healthcare. The conversation touches on real-world use cases, the challenges of distributed ...
Loïc Houssier, Head of Engineering at Superhuman, joins us to discuss how AI and LLMs are reshaping the email experience. He highlights challenges related to the variability of user prompts and infrastructure optimization. Loïc emphasizes that a deep focus on user experience and real human workflows is key to building AI tools people actually love to use.
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In this episode, Daniel and Chris unpack the Model Context Protocol (MCP), a rising standard for enabling agentic AI interactions with external systems, APIs, and data sources. They explore how MCP supports interoperability, community contributions, and a rapidly developing ecosystem of AI integrations. The conversation also highlights some real-world tooling such as FastAPI-MCP.
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In this episode, we explore the intersection of AI, machine learning, and healthcare through the lens of neuroimaging and epilepsy diagnosis. Dr. Gavin Winston shares insights from his work using MRI data and machine learning to uncover subtle abnormalities in brain function. We discuss the cultural and ethical barriers to AI adoption in medicine, how predictive data analysis could transform the diagnostic workflow, and wh...
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