Prevention is Cure

Prof. Grant Schofield explains ketosis from first principles: what it is, why it matters, and how it differs from simply "eating low carb." We talk about insulin resistance and metabolic syndrome, which affect a significant share of adults today, the surprising wartime origins of chemotherapy.

Prevention is Cure is sponsored by Prekure - a New Zealand education organisation with a bold vision: to redefine the future of medicine. Pr...

In this episode, Grant Schofield sits down with ocean swimmer and activist Jono Ridler, fresh off an extraordinary feat: swimming just shy of 1,400km from North Cape to Wellington in just 90 days.

Jono shares what drove him to take on the swim, the physical and mental toll of months in open water, and the deeper mission behind it: raising awareness of what's happening beneath the surface of our oceans, including the impact of bottom...

Prof Grant Schofield and Dr Louise Schofield are embarking on their annual 5-day fast, and they're sharing everything: the science, the struggles, and the practical tips that make it work.

Whether you're fasting-curious or a seasoned faster, this is the honest, science-backed conversation you need before you start.

Follow along on socials: Prof Grant Schofield & Dr Louise Schofield on Facebook, LinkedIn, and Instagram.

A Herald story revealed New Zealand households spend $20 million a year on energy drinks, and some people are drinking two litres a day just to get through a shift. In this episode Prof. Grant Schofield and guest co-host, Sam Schofield unpack the predatory marketing with energy drinks aimed squarely at young boys, why a single 500ml can hides 13 teaspoons of sugar and 160mg of caffeine, and the B6 toxicity risk almost nobody talks ...

In this episode of Prevention Is Cure, Prof Grant Schofield and Sam Schofield dive deep into the most explosive topic in metabolic health right now - have we actually cracked weight loss and aging? From the latest GLP-1 triple agonists showing 30% body weight loss, to gene therapies that can reverse the age of individual cells, the science is moving faster than most people realise.But here's the uncomfortable truth: 9 out of 10 peo...

Prof Grant Schofield speaks with Paul Alden, a 38-year veteran firefighter turned author about his upcoming book The Amplified Mind. Drawing on his experience watching EMTs lose critical thinking capacity when protocols replaced diagnostic reasoning, Paul draws a striking parallel to what's happening right now with AI adoption across every profession.

They explore why the sequence matters, generating your own ideas before turning to...

From the Hardiness podcast with Dr Paul Taylor

If you think ease and comfort are the keys to happiness, think again. This episode explores how deliberately embracing life's challenges, through movement, fasting, cold exposure, and mental resilience, can transform your health, happiness, and purpose. Grant Schofield, an esteemed researcher and author, reveals that life's true reward lies in choosing the hard path, strong in the knowl...

Prof Grant Schofield is joined by Sam Schofield on this episode that dives deep into the placebo, and 'nocebo' effect, exploring how belief, self-narrative, and perceived feedback can measurably change your physiology, performance, and recovery. From Roger Bannister's four-minute mile to sham knee surgeries, sleep score dangers, and the milkshake study, this episode makes the case that the mind is the most underused lever in health...

Prof. Grant Schofield and Kayla dive into the science and break down the five key hormones controlling appetite, insulin, leptin, ghrelin, the incretins (GIP & GLP-1), and cortisol and explain why willpower alone can never beat a dysregulated hormonal system. They explore metabolic flexibility, why cycling in and out of ketosis is normal human physiology (not a fad), and how exercise context should drive your fuelling strategy....

What if the secret to a long, healthy life isn't making things easier, it's choosing the right kind of hard?

In this episode, Prof. Grant Schofield and Kayla sit down to celebrate the launch of Grant's new book, Choose Your Hard: The Science of Doing Hard Sh*t to Build Health That Lasts a Lifetime.

They unpack the seven truths behind lasting health and performance, from the biology of hormesis and the dopamine trap, to nutrition, f...

Grant and Kayla follow up on Claude's viral AI essay with Claude's own response, they unpack new research on AI-induced "delusional spirals," a Nobel laureate economist's dire warning about AI and human thinking, and the cultural moment we're in with films like WALL-E and Good Luck, Have Fun, Don't Die.

Then stay tuned to hear about nutrition: the omega-3 to omega-6 ratio crisis, a landmark 1.8-million-person study on vegan diets an...

Prof. Grant Schofield and Kayla dive into five groundbreaking scientific papers that challenge conventional wisdom about health and technology.

Discover why exercise signals your entire body to heal, how Swedish women who avoided sunlight faced mortality risks equal to smoking, and why eating earlier in the day beats traditional intermittent fasting.

Plus: the shocking evidence proving social media harms teens (backed by Meta's own...

Is fibre actually the health hero we've been told it is? Prof. Grant Schofield and Kayla dive deep into the science behind fibre recommendations and expose how food companies game the system. From the surprising truth about constipation to why cows eating grass end up on a high-fat diet, this episode challenges everything you thought you knew about fibre.Key Takeaways:• Why dietary fibre guidelines might be doing more harm than goo...

What if every technological leap forward has been a metabolic leap backward? Prof. Grant Schofield and Kayla trace humanity's journey from thriving hunter-gatherers to chronically diseased modern humans and explore whether AI might be the final mismatch.

The hosts reveal how agriculture halved our life expectancy and shrunk our brains, how the industrial revolution trapped families in dual-income dependency, and how smartphones stol...

Modern medicine excels at treating sickness, but fails spectacularly at creating health. Even with compelling data proving treatments don't work (or cause harm), medicine often doubles down.

Grant and Kayla explore why and unpack the disturbing reality behind common medical interventions: knee surgeries with infinity NNT (number needed to treat), back pain procedures causing more harm than good, and psychiatric medications that bar...

Willpower is a lie. Your brain is even wired to betray your future self. So how do you actually change?

Grant and Kayla dive into the philosophy and science behind lasting behaviour change, from Pascal's 17th-century logic (applied to your metabolism) to the marshmallow experience. You'll discover why discipline isn't about toughing it out and learn the Ulysses Pact strategy, why small "harmless" choices can compound over time into ...

We are back for 2026! When your doctor prescribes medication without explaining that lifestyle changes could reverse your condition, is that ethical? Legal? This episode challenges the pharmaceutical-first approach dominating modern medicine.

You'll learn why defaulting to drugs for metabolic disease violates medical ethics, how the UK's Montgomery ruling is changing what doctors must disclose, and what "number needed to treat" reve...

In this episode, Grant speaks with Gareth Holebrook, President of North Harbour Tri Club, PREKURE Health Coach, and business coach, about leadership, influence, and why instruction alone rarely creates change.

Gareth’s leadership philosophy has been shaped by an unconventional career path. Thirty years ago, he served in the Royal Navy as an engineer, with ambitions to become an engineering officer. After being made redundant i...