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August 31, 2025 35 mins

In this episode, our guest is Sam Libby, President and Managing Director of TCB Capital Advisors. Sam's long-standing career in healthcare investment banking has seen him lead over 30 impactful transactions, totaling more than $20 billion. His dedication to healthcare is rooted in a personal connection, being the son of two therapists, which has given him a unique understanding of the sector's challenges, particularly around patient access and care quality.

As co-founder of TCB Capital Advisors, Sam focuses on empowering forward-thinking healthcare companies. His work spans partnerships with companies in oncology, neurodegenerative diseases, women's health, and digital health, helping to steer innovations that profoundly improve patient outcomes. 

Sam, welcome to the Talk to Your Pharmacist podcast. Now that our listeners have heard a bit about your background maybe you can fill in any gaps to that intro and share a bit about your personal life.


Topics to discuss –

Background & Career

  1. Sam, you’ve had an incredibly successful career in healthcare investment banking, leading over 30 transactions totaling more than $20 billion. Can you walk us through how you first became interested in the healthcare sector, and how your upbringing as the son of two therapists shaped your perspective on healthcare?
  2. As co-founder of TCB Capital Advisors, how did you identify the unique opportunity to focus specifically on healthcare companies? What challenges did you face in the early days of building your firm?

Healthcare Investment Landscape

  1. You've been involved in transactions across diverse areas, such as oncology, neurodegenerative diseases, women’s health, and digital health. How do you assess which healthcare innovations and companies are worth investing in? What are some key trends you’re seeing in these sectors today?
  2. Healthcare investment banking involves navigating both financial and clinical challenges. How do you balance the business side of healthcare with the real-world impact on patient access and care quality?
  3. You’ve been part of some transformative partnerships in healthcare. Can you share a specific example of a partnership that particularly stands out to you, both in terms of financial success and its impact on patient outcomes?

Healthcare Innovation & Strategy

  1. With your experience empowering forward-thinking healthcare companies, how do you foresee digital health and technology playing a larger role in the future of patient care? What do you think are the biggest opportunities and challenges?
  2. Women’s health is one of the key sectors you’ve focused on. What are some innovations or initiatives you’ve seen that are making a real difference for women’s healthcare, and how can investors further support these efforts?
  3. In your opinion, what role does patient access play in the broader healthcare investment landscape? How can companies balance innovation with the need to make these innovations accessible to all patients, especially underserved populations?

Financial Strategies & Healthcare Companies

  1. Healthcare investments often involve complex financial strategies. For our audience who might not be familiar with the intricacies of healthcare investment banking, can you explain how financial strategies differ when working with healthcare companies as opposed to other industries?
  2. As a leader in healthcare investment banking, how do you guide companies through challenges like market volatility, regulatory hurdles, and competition in their efforts to innovate and grow? Are there any specific strategies you use to help them thrive?

Future Outlook

  1. You’ve helped shape the growth of companies across a wide range of therapeutic areas. Looking ahead, what sectors or healthcare innovations do you believe have the most potential to revolutionize patient outcomes in the next 5 to 10 years?
  2. As someone deeply involved in healthcare strategy and innovation, what advice would you give to young entrepreneurs or companies just starting to navigate the healthcare sector? What are the key lessons you’ve learned along the way?
  3. Lastly, what excites you most about the future of healthcare, and where do you see the biggest areas for disruption and opportunity?

Guest - Sam Libby, TCB Capital Advisors


Host - Hillary Blackburn, PharmD, MBA

www.hillaryblackburn.com


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