All Episodes

October 27, 2025 50 mins

In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Conor H. Murray, a neuroscientist at UCLA whose research explores how psychedelics affect the brain.

Find full show notes and links here:
https://thethirdwave.co/podcast/episode-327/?ref=278 

Conor shares insights from his placebo-controlled LSD microdosing study revealing measurable increases in neural complexity, suggesting unique neurological benefits even at sub-perceptual doses. He and Paul discuss what these findings mean for depression, addiction, and brain plasticity, as well as the future of citizen neuroscience through Conor's platform Psynautics. They also touch on his ongoing psilocybin study for cocaine use disorder and why low-dose research may hold keys to understanding consciousness itself.

Interested in participating in Dr. Murray's Microdosing Study? Get 10% Off Your Enrollment!
Use code WAVE3 to receive 10% off your study kit. https://www.psynautics.com/microdosing

Conor Murray is a neuroscientist specializing in altered states of consciousness at UCLA. He is also the founder of Psynautics, the world's first citizen neuroscientist platform built for testing hypotheses related to altered states of mind and brain, from meditation to microdosing. His scientific expertise spans from the neurobiology of addiction to the effects of cannabis and psychedelics on the brain.

Highlights

  • How Dr. Murray entered psychedelic research by chance
  • What LSD microdosing reveals about neural complexity
  • The "sweet spot" around 13 micrograms for mental clarity
  • Why placebo effects don't fully explain brain changes
  • Microdosing vs macrodosing in neuroplastic outcomes
  • BDNF, inflammation, and the mechanisms of healing
  • Psilocybin's potential for cocaine use disorder
  • How environment influences addiction and relapse
  • The rise of citizen neuroscience and DIY EEG studies
  • Where psychedelic science is headed next

Episode Links

Episode Sponsors

Mark as Played

Advertise With Us

Popular Podcasts

On Purpose with Jay Shetty

On Purpose with Jay Shetty

I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!

Dateline NBC

Dateline NBC

Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

Stuff You Should Know

Stuff You Should Know

If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2026 iHeartMedia, Inc.