Week 12 College Football Picks for the 10 Biggest Games! 2025

It’s Week 12, and the slate is LOADED — ten marquee matchups with playoff and conference title implications. Gary’s back with model projections, power ratings, and ATS picks for every major showdown.We cover Notre Dame–Pitt, Michigan–Northwestern at Wrigley, Iowa–USC, Oklahoma–Alabama, Virginia–Duke, South Florida–Navy, Utah–Baylor, Florida–Ole Miss, Texas–Georgia, and TCU–BYU under the lights in Provo.Every game breakdown includes PPA margin, finishing drives, success rates, and home/road ATS splits to help you find real betting edges. We discuss playoff paths for Notre Dame and Texas, potential upsets from Iowa and Oklahoma, and why Ole Miss and Utah are primed to roll.If you enjoy analytical, data-backed college football talk, subscribe, like, and drop your Week 12 picks in the comments.Get full stat sheets, matchup tools, and official plays at bettingcfb.com or www.buymeacoffee.com/winningcures.Keywords: Week 12 college football, Notre Dame vs Pitt, Georgia vs Texas, Alabama vs Oklahoma, Utah vs Baylor, Ole Miss vs Florida, TCU vs BYU, Winning Cures Everything, GaryWCE.

• 1:14 Notre Dame vs Pitt
• 6:22 Michigan vs Northwestern
• 10:59 Iowa vs USC
• 15:59 Oklahoma vs Alabama
• 22:18 Virginia vs Duke
• 25:37 South Florida vs Navy
• 29:21 Utah vs Baylor
• 33:08 Florida vs Ole Miss
• 37:24 Texas vs Georgia
• 42:26 TCU vs BYU

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