Angel Invest Boston

Angel Invest Boston

In the Decade of Biotech when there will be myriad opportunities to invest in angel-scale biotech startups. After decades of angel investing, I am focusing on the life science side of my portfolio and invite other angels to do the same. Here's why: https://www.labcoatventures.com/why-we-are-focused-on-early-stage-biotech/ I’m Sal Daher, host of the Angel Invest Boston Podcast. After immigrating to Boston as a child and attending Belmont High School, I studied engineering at MIT and Stanford. Decades of work in international finance followed. During that time, I invested in a handful of ventures founded by friends and acquaintances. Now, I’m a member of Walnut Ventures and MIT Angels and spend most of my time as an angel investor. Startups in my portfolio include: SQZ Biotech, Gelesis, Akili Interactive, Vedanta Biosciences, FineTune Learning, Concrete Sensors, Squadle, doDoc, Pixability, Mavrck, Viral Gains, Streamroot, XMOS, Alice's Table and others. Exits include: Exos (Microsoft), Rifiniti (KKR) and PIKA Energy (Generac).

Episodes

December 29, 2023 38 mins

In the final episode of the podcast I, Sal Daher, review important lessons I learned in seven years of interviews and decades of investing. In my voice and in the voice of my guests, I recapitulate the discoveries most salient to me and invite listeners to find their own nuggets in the sound archive which will remain available on Apple Podcasts and other platforms. AngelInvestBoston.com will have 250 episode pa...

Mark as Played

Lessons Learned is a compilation of hard-won lessons in angel investing. They come from my podcast interviews over these seven years as well as from my three decades of angel investing. Hints on how to build your portfolio, how to eliminate sure losers and other practical advice will be offered in the voice of my guests and in my own voice. Sorry that the release of the episode is delayed until Friday 12/29 due to personal matters ...

Mark as Played
December 20, 2023 45 mins

Aging Fit Substack: Learn More

 

Repeat life science entrepreneur Tom Weldon is now taking on aging. He is commercializing a compound to extend health span developed at a prominent institution. Composed of substances generally considered as safe by the FDA, the formula has shown impressive results in mice and, to date, in one human, Tom himself. Int...

Mark as Played
December 13, 2023 35 mins

Aging Fit Substack: Learn More

 

Raul Rosa, artist, musician, and sound engineer, discusses his work with the Angel Invest Boston Podcast, some of his favorite interviews, and his own startup, Podspot.

 

Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.

Mark as Played

Aging Fit Substack: Learn More

 

In my fourth decade of angel investing, I’m happy with my investments but regret having put them in my IRAs. Here are pros and cons of having illiquid, operationally complex and hard-to-value assets in IRAs.

 

Sponsored by Purdue University entrepreneurship and Peter Fasse, patent a...

Mark as Played

Aging Fit Substack: Learn More

 

Life science board member and advisor Paul Hartung is back with wise tips on how to fund your biotech startup in these had times. Listen or read below.

 

Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.

 

Mark as Played

Aging Fit Substack: Learn More

 

Katharine Woodman-Maynard has for seven years created a gorgeous and enduring graphic manifestation of this podcast on the web. I am fortunate to have this gifted artist enhancing my work with her talent and wisdom. She returns to talk about her favorite interviews, to share her journey as a professional artist and t...

Mark as Played
November 29, 2023 35 mins

Aging Fit Substack: Learn More

 

Ethan Pierce’s startup Adaptive Reader makes great literature accessible to kids not reading at grade level. Harnessing generative AI with sophisticated prompts and quality control by humans creates compelling texts based on the classics. Ethan and his co-founder even have a promising business model. Great chat!

Mark as Played
November 22, 2023 41 mins

Angel Scale Biotech: Learn More

 

Brian Denenberg is an angel investor, company advisor, and co-founder. Here, he discusses some of the companies he has been involved with, including Fairmarkit, Tive, and his work at Venture Lane Studio helping startups grow sales.

 

Sponsored by Purdue University entrepreneurship ...

Mark as Played
November 15, 2023 44 mins

Angel Scale Biotech: Learn More

 

Brian Freeman, MD, co-founded Energesis to help overweight people lose weight by growing their energy-burning brown fat. Experiments in mice have shown this approach works with GLP-1 drugs such as Wegovy in accentuating weight loss. Great chat with a compelling repeat founder.

 

Sp...

Mark as Played

Angel Scale Biotech: Learn More

 

My Walnut buddy Andy Bartlett, PhD brings great energy to the group and an expert’s perspective on computing. We talked about our favorite startups including Savran Technologies, evTS, and BioFeyn. He has interesting things to say about ChatGPT. We also had a great chat about his angel journey.

...

Mark as Played
November 1, 2023 50 mins

Angel Scale Biotech: Learn More

 

Kevin Majeres, MD, teaches cognitive behavioral therapy (CBT) at Harvard Medical School. CBT is the gold standard to treat mental health conditions without drugs. CBT can also help with workplace issues such as burnout or anxiety. Dr. Majeres (pronounced Majors) has built a digital platform, OptimalWork.com, to impr...

Mark as Played
October 25, 2023 41 mins

Jason Burke wants a better way for angels to invest in startups. He founded All Stage, the platform for angel investing that powers TBD Angels which he also co-founded.  In this illuminating interview Jason discusses how All Stage helps the angel ecosystem. We also chatted about Moolah Kicks, and Folia Health.

Her...

Mark as Played

Angel Scale Biotech: Learn More

 

Brazilian startup MirScience Therapeutics is working on reversing muscle loss. I had an illuminating chat with co-founder Milena Peregrino, PhD about the technology and the company’s progress. 

 

Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fi...

Mark as Played

Repeat founder Agustin Lopez Marquez, ex-nference, brings his AI savvy to food delivery with his new startup. Built on CloudKitchens’ infrastructure, Mowgli addresses pain points for diners, sous-chefs and drivers. Loved my chat with this brilliant and practical founder. Sample Mowgli’s homey meals from exotic places at https://khipi.com/. (delivers only to Boston & Cambridge for n...

Mark as Played
October 4, 2023 45 mins

Angel Scale Biotech: Learn More

 

Repeat founder Todd Zion, PhD is back to update us on exciting developments at his second biotech startup, Akston Bio. We also geeked out a bit on how these magical proteins are concocted in the company’s bioreactors. Fun and instructive chat with a stellar founder.

 

Sponsored by ...

Mark as Played

Angel Scale Biotech: Learn More

 

Rather than purloin my kids' Ritalin, I play EndeavorOTC daily to improve my attention and be sharper. Eddie Martucci, PhD is the founder of Akili that developed the app which is backed by real science. In fact, the kid's version is FDA-cleared to treat ADHD in 8-12 year olds. Don't miss this great chat. 

 

Sponsored by Purdue University entrepreneurship and ...

Mark as Played
September 20, 2023 28 mins

Angel Scale Biotech: Learn More

 

The third time is the charm for Piction Health. Super founder Susan Conover is back to talk about the third iteration of their business model which is showing promise of scaling profitably. Her AI has ingested a million diagnosed images of hair and skin conditions and is now making dermatologi...

Mark as Played
September 13, 2023 37 mins

Angel Scale Biotech: Learn More

 

Rotator cuff tears are debilitating. What if you could take action to avoid them? Rabeeh Majidi, PhD founded OrthoKinetic Track to do just that through a wearable device and a predictive algorithm. Listen to our chat to learn more. 

 

Sponsored by Purdue University entrepreneurship...

Mark as Played

Angel Scale Biotech: Learn More

 

Richard Vlasimsky is using AI to create a low-cost way of vastly expanding our ability to detect lung cancer early. His algorithm for detecting lung nodules in chest x-rays just got FDA clearance. Listen to this remarkable founder who’s done a lot with modest funding.

 

Sponsored b...

Mark as Played

Popular Podcasts

    Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.

    24/7 News: The Latest

    The latest news in 4 minutes updated every hour, every day.

    Stuff You Should Know

    If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

    The Clay Travis and Buck Sexton Show

    The Clay Travis and Buck Sexton Show. Clay Travis and Buck Sexton tackle the biggest stories in news, politics and current events with intelligence and humor. From the border crisis, to the madness of cancel culture and far-left missteps, Clay and Buck guide listeners through the latest headlines and hot topics with fun and entertaining conversations and opinions.

    The Bobby Bones Show

    Listen to 'The Bobby Bones Show' by downloading the daily full replay.

Advertise With Us
Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.