Big Picture Science
The surprising connections in science and technology that give you the Big Picture. Astronomer Seth Shostak and science journalist Molly Bentley are joined each week by leading researchers, techies, and journalists to provide a smart and humorous take on science. Our regular "Skeptic Check" episodes cast a critical eye on pseudoscience.
Episodes
October 13, 2025 • 56 mins
Long before Orson Welles provoked a panic with his 1938 radio broadcast of a Martian invasion in War of the Worlds, we were fascinated with the possibility of life on the Red Planet. We may be a step closer to finding it after the Perseverance rover turned up tantalizing evidence of possible ancient life in the form of mineral deposits in a Martian rock. But to be sure, we need to test that rock sample in a lab here on Earth, and t...
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October 6, 2025 • 54 mins
The tiny bean-shaped structures in your cells – mitochondria – are little powerhouses. Recent research suggests they may unlock overall good health, or, when they fail, cause diseases such as diabetes and Alzheimer’s. How strong is the science for these claims and what, if anything, should we be doing to improve our mitochondrial health? Should we take a cue from influencers who suggest drinking an industrial dye called methylene b...
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September 29, 2025 • 54 mins
We’re hurtling towards a post-antibiotic world, as the overuse of antibiotics has given rise to dangerous drug-resistant bacteria. Can we fight back using viruses as weapons? An obscure medical therapy uses certain viruses called bacteriophages to treat infection. For a century attempts to turn phage-therapy into a life-saving treatment have faltered, but today there’s renewed interest in this approach. Can we use phages to foresta...
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September 22, 2025 • 54 mins
Strapped-on brass noses, frog skin grafts, human organs grown in pigs: The world of replaceable body parts is both amazing and a bit unsettling. But who better give us a tour of the past and present of what medical engineering considers Plan B, than the inimitable science writer Mary Roach.
Guest:
Mary Roach – Science writer and author of “Replaceable You: Adventures in Human Anatomy”
Featuring music by Dewey Dellay and Jun Miya...
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September 15, 2025 • 57 mins
As their name suggests, “forever chemicals” have extraordinary staying power. When these nearly indestructible compounds find their way into our soil and water, they don’t break down for hundreds or thousands of years. PFAS – the name for these synthetic chemicals – isn’t just in our natural environment. Scientists have found it everywhere, including in the blood of nearly every living being.
In this episode, we talk to the repor...
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September 8, 2025 • 54 mins
Have scientists discovered an alphabet in whale calls? As researchers try to decipher the series of clicks made by sperm whales, we ask whether these cetaceans might have language, and if it follows that whales are thinking animals too. Could we one day get a peek into the thoughts of a humpback whale? Meanwhile, somewhere along the long path of evolution, one species emerged with an impressive gift for gab. Are speech and language...
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September 1, 2025 • 54 mins
We are closer than ever to finding aliens according to astrophysicist Adam Frank. He isn’t alone in his optimism. Over the last two decades, the tools used to search for extraterrestrials have been advancing mightily. Where we were once only monitoring with radio telescopes, we are now actively looking for bio and technosignatures on exoplanets. Find out why scientists think new technology may be a game changer in the hunt for life...
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August 25, 2025 • 54 mins
A canopy of stars in the night sky is more than breathtaking. Starlight is also an important tool that astronomers use to study our universe. But the growth of artificial light and light pollution are creating dramatic changes to the nighttime environment. Let your eyes adjust to the dark as we travel to a dark sky reserve to gaze upon an increasingly rare view of the Milky Way and explore what we lose when darkness disappears.
...
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August 18, 2025 • 65 mins
“The Mississippi River will always have its own way; no engineering skill can persuade it to do otherwise,” said Mark Twain. In this, our final episode marking the 20th anniversary of Hurricane Katrina, we consider how efforts to control the Mighty Mississippi – a river engineered from its Minnesota headwaters to its Gulf Coast outlet – have responded to the devastating storm, and how New Orleans’ relationship to the river has chan...
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August 11, 2025 • 59 mins
Ever heard of a beauty quark? How about a glueball? Physics is full of weird particles that leave many of us scratching our heads. But these tiny particles make up everything in the quantum world and in us and are the basis of the fundamental scientific theory called The Standard Model. But it doesn’t explain everything. It can’t account for dark matter or dark energy, for example. We find out whether new physics experiments might ...
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August 4, 2025 • 54 mins
Telescopes are like light buckets. The bigger the telescope, the more light collected for astronomers to observe. With recent advances in technology, amateur astronomers can join professionals for a chance to observe stellar nurseries and exoplanets many light-years away. But as our capabilities increase, so do the mysteries, including those around high-energy bursts coming from an otherwise unremarkable part of the universe. Under...
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July 28, 2025 • 58 mins
They are known for holding branches in their paws and gnawing on them like corn cobs. They build lodges and dams which occasionally flood roads. Cute, comical, and considered pests, beavers were nearly hunted to extinction for their pelts before conservation efforts allowed their populations to rebound. Now environmentalists and engineers are reintroducing North America’s largest rodent to drought-prone habitats across the country....
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July 21, 2025 • 59 mins
Has children’s play become too safe? Research suggests that efforts to prioritize safety harms children’s mental and physical development during play and contribute to anxiety. One solution: introduce risk into play. We visit an adventure playground where kids play unsupervised with anything from scraps of metal to hammers and nails. Plus, what are the evolutionary benefits of play? After all, we’re not the only species who like to...
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July 14, 2025 • 54 mins
How frequently do you think about fasteners like screws and bolts? Probably not very often. But some of them a storied history, dating back to Egypt in the 3rd century BC. They aren’t just ancient history. They help hold up our bridges and homes today. Join us as we dissect a handful of engineering inventions that keep our world spinning and intact.
Guests:
Roma Agrawal - structural engineer and author of "Nuts and Bolts: Seven S...
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July 7, 2025 • 54 mins
Drinking a cup of coffee is how billions of people wake up every morning. But climate change is threatening this popular beverage. Over 60% of the world’s coffee species are at risk of extinction. Scientists are searching for solutions, including hunting for wild, forgotten coffee species that are more resilient to our shifting climate. Find out how the chemistry of coffee can help us brew coffee alternatives, and how coffee ground...
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June 30, 2025 • 54 mins
What physical activity gives you joy? Whether it’s walking, running, dancing or swimming, your body evolved to do it. We are made for movement. But there’s a cost, as anyone with a sore neck or aching back knows. From the tiny muscles in our skin, which raise the hair on our arms, to the intricate mix of bone, blood vessels, and nerves in our neck, natural selection has struck a delicate and sometimes wacky balance between utility ...
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June 23, 2025 • 54 mins
Healthy rivers and riparian ecosystems are teaming with life, but should rivers themselves be considered alive? The question is central to the growing rights-of-nature movement that claims that ecosystems and entities, like rivers, have legal rights. After Ecuador enshrined the rights of nature in its constitution, lawyers employed the new personhood status to stop mining companies from clearing a section of the Los Cedros River an...
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June 16, 2025 • 54 mins
The discovery of a massive amount of lithium under the Salton Sea could make the U.S. lithium independent. The metal is key for batteries in electric vehicles and solar panels. But the area is also a delicate ecosystem. We go to southern California to hear what hangs in the balance of the ballooning lithium industry, and also how we extract other crucial substances – such as sand, copper and iron– and turn them into semiconductors...
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June 9, 2025 • 54 mins
Whales are aliens on Earth; intelligent beings who have skills for complex problem-solving and their own language. Now in what’s being called a breakthrough, scientists have carried on an extended conversation with a humpback whale. They share the story of this remarkable encounter, their evidence that the creature understood them, and how the experiment informs our Search for Extraterrestrial Intelligence. After all, what good is ...
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June 2, 2025 • 55 mins
A big challenge during a hurricane or other disaster is keeping lines of communication open when the power goes out. In this episode, the second in our series tied to the 20th anniversary of hurricane Katrina, we report from the National Hurricane Conference in New Orleans about a technology used in 2005, and still employed today, to provide vital information during a crisis. In our age of growing reliance on cellphones and funding...
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