Liver, Life & Survival

In this powerful episode of the Connecticut Book Festivals podcast, host Jed Lee sits down with John Hoffman, author of "Liver: My Journey of Transplant Survival," to share an extraordinary story of medical resilience, hope, and personal transformation. Diagnosed with biliary atresia at just eight weeks old, Hoffman underwent his first experimental liver transplant in 1981 when liver transplants for infants were still a groundbreaking procedure. Growing up with a massive surgical scar and daily medications, he navigated childhood with remarkable normalcy, participating in sports and maintaining close friendships. By his freshman year of high school, Hoffman faced the reality of needing a second liver transplant. Despite the emotional and physical challenges, he maintained a positive outlook, inspired by his parents' unwavering support. The second transplant in 1999 marked a turning point, leading him through a journey of recovery, depression, and ultimately, personal growth. Hoffman's book isn't just a medical memoir—it's a testament to the human spirit. After struggling with depression and feeling directionless, he found purpose in sharing his story. His message is clear: never give up hope and consider becoming an organ donor. The podcast episode highlights Hoffman's key motivations for writing the book, including honoring his family's perseverance and inspiring others facing similar medical challenges. He candidly discusses his experiences, from survivor's guilt to his recent health transformation, which included losing 40 pounds and adopting a healthier lifestyle. Listeners can find more about John's journey at johntransplantjourney.com, where they can purchase the book in multiple formats, including a recently released audiobook. This episode is a must-listen for anyone interested in medical memoirs, organ donation awareness, and stories of incredible personal resilience.