Combating Sarcopenia with Peptides with Dr. Andy Franklyn-Miller

Dr.Andy Franklyn-Miller is a world-leading specialist in sport and exercise medicine and the Chief Medical Officer at Nuritas. He is a highly accomplished physician with expertise in physiology, clinical design, and science communication, has a Ph.D. in Biomechanics, and served in the Royal Navy and Royal Marines for 16 years. Dr. Franklyn-Miller has extensive experience in working with high-profile sports teams and elite performers, has published more than 60 peer-reviewed papers, is an editor of the British Journal of Sports Medicine, and has authored a textbook and an IOC Handbook. With his expertise in machine learning, clinical trials, and end-user analysis, he oversees several departments at Nuritas, including software engineering, data curation, data science, proteomics, lab, and regulatory departments. Together, Dr. Franklyn-Miller and I explore the science behind PeptiStrong, a groundbreaking peptide developed by Nuritas, and discuss its clinical applications and research. If you have patients who are concerned with muscle retention as they age, who aren't recovering as quickly as they would like after exercise, or who are on GLP-1 medications and need to retain lean muscle mass, this conversation will be particularly engaging to you. Together, we cover the latest peptides data and studies and what it all means for healthcare practitioners. 

 

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

 

Episode Resources:

Dr. Andy Franklyn-Miller - https://www.nuritas.com/team/dr-andy-franklyn-miller/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Designs for Health Practitioner Exclusive Drug Nutrient Depletion and Interaction Checker - https://www.designsforhealth.com/drug-nutrient-interaction/

Visit the Designs for Health Research and Education Library, which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

The Designs for Health Podcast is produced in partnership with Podfly Productions.

Chapters:

00:00 Intro.

02:28 Dr. Franklyn-Miller is feeling lit up by his current data analyses.

3:00 The ability to increase health in millions of people drew Dr. Franklyn-Miller to Nuritas.

4:02 What are peptides, and what are their function and benefits related to athletic performance?

7:33 Does PeptiStrong negatively impact those with a G6-PD deficiency?

8:52 Why don't PeptiStrong peptides break down as amino acids?

11:33 Three human clinical studies and their results and mechanisms of action.

14:09 The importance and controversy of the mTOR 1 and 2 pathways.

17:19 Key findings about muscular energy from the second human study.

20:58 Factors that effectively inhibit pathways that lead to sarcopenia.

22:22 The third study examines the impact of PeptiStrong on both men and women.

24:59 The impact of PeptiStrong on reducing inflammation and the effect on TNF-Alpha and on ATP production.

28:12 Prioritizing creatine, HMB, and leucine benefits with peptides in a synergistic way.

30:27 Creating optimal impact of PeptiStrong on various patient outcomes.

33:04 Studies that will address muscle mass at each stage of a woman's life.

38:52 Clinical guidelines for taking peptides to maximize effectiveness.

40:09 Observations from Dr. Franklyn-Miller's personal experience with taking PeptiStrong.

43:36 Optimal designs for future clinical trials and the role of peptides in shaping the future of healthcare.

55:35 Dr. Franklyn-Miller's personal favorite supplements, favorite health practices, and his evolved perspective on what food and medicine are really about.