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October 23, 2025 β€’ 4 mins

πŸ” New in The Lancet! A massive network meta-analysis of 94 RCTs (105,435 patients) reveals that antidepressants impact far more than mood πŸ§ β€”they alter weight βš–οΈ, glucose 🩸, BP πŸ’“, lipids 🧬, and liver enzymes πŸ§ͺ.

Agomelatine πŸŒ™ may lower weight, while nortriptyline πŸ“ˆ raises heart rate. Time to rethink side-effect profiles when prescribing!

πŸ“š Pills, Pressure, and Physiology β€” catch the full summary & clinical pearls now!

Β 

#Antidepressants #CardiometabolicHealth #Depression #PrecisionMedicine #Lancet πŸ§ πŸ’Šβš–οΈ

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