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October 31, 2025 โ€ข 4 mins

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๐Ÿ“ข New Study Alert ๐Ÿฉบ๐Ÿ’Š In JAMA Internal Medicine, a national analysis reveals that using the PREVENT risk calculator (vs Pooled Cohort Equations) dramatically reduces the number of U.S. adults aged 40โ€“59 eligible for aspirin in primary prevention of cardiovascular disease. Among 7.6 million current aspirin users, >96% wouldn't qualify by PREVENT ๐Ÿคฏ. Time to rethink our calculators and consider deprescribing where net benefit is questionable.

๐Ÿ“ฐ Read more: https://jamanetwork.com/journals/jamainternmed/fullarticle/10.1001/jamainternmed.2025.5049

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