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March 31, 2025 56 mins

I’m excited to have Dr. David Perlmutter back on the podcast to discuss uric acid and its pivotal connection to our overall health. Which foods lower and raise uric acid? What is its role in diabetes, alzheimer’s, gut health, and brain health? All of this will be covered, as well as best protocols for lowering high uric acid. You don’t want to miss this! Listen now! 

Learn more about lowering uric acid in Dr. Perlmutter’s book, Drop Acid! 

https://drperlmutter.com/learn/books/

Connect with Dr. Perlmutter online:

https://www.instagram.com/davidperlmutter/

www.drperlmutter.com

Need help navigating your digestive or other health conditions? Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

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https://www.youtube.com/watch?v=uyJQSDY0gRc

➡️Top Nutrient Dense Foods You Should Be Eating With Dr. Sarah Ballantyne:

https://www.youtube.com/watch?v=76i5lWM8kNo

 

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

 

👇Read these next 👇

➡️ How to Heal Your Gut Naturally: A Clinician’s Guide

https://drruscio.com/how-to-heal-your-gut-naturally/ 

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https://drruscio.com/blood-sugar-spikes/ 

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https://drruscio.com/best-microbiome-supplements/ 

 

Timestamps

00:00 Intro 

01:30  Why uric acid is pivotal to health

05:57 Evolutionary origins of high uric acid

07:12 Why fructose is a major factor

13:10  What elevates uric acid?

18:47 How to monitor levels

24:22 Foods that raise vs. lower UA 

25:43 Relation to diabetes & other diseases

29:40 Probiotic protocol to lower UA

31:39 Connection to gut health

35:59 Connection to brain health

44:10  New therapeutics to explore

52:49 How to lower uric acid

57:37 Final takeaways

 

Featured Studies 

📉Safety and efficacy of probiotic supplementation in 8 types of inflammatory arthritis:

https://pubmed.ncbi.nlm.nih.gov/36217542/

📉Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric

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