In this episode of CardioNerds Journal Club, Jeanne du Fay de Lavallaz, MD and Ramy Doss, MD are joined by Varun Sundaram, MD, and Sanjeev Saksena, MBBS, MD, FHRS to break down the TRANSFORM-AF trial — a groundbreaking study from the Veterans Affairs health system examining how GLP-1 receptor agonists influence outcomes in patients with atrial fibrillation (AF). The panel unpacks the science connecting metabolic health and arrhythmia burden, key insights from this large real-world cohort, and what it all means for managing AF in patients with obesity and diabetes. They also explore how multidisciplinary collaboration and population-scale data are shaping the future of preventive electrophysiology.
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