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April 1, 2025 53 mins

Hormones play a crucial role in both men's and women's health. I recently had the pleasure of chatting with Dr. Pamela Smith on the Hustle and Flowchart podcast about this important topic, especially focusing on male hormones and how they affect entrepreneurs like us. Dr. Smith shared valuable insights on hormonal balance and its connection to our health, energy, and ability to stay productive in our busy lives. Let's dive into the key points we discussed in the episode.

What The Episode Is About

In this episode, Dr. Pamela Smith sheds light on the importance of hormones for both men and women. Most of us often neglect understanding how vital hormones are in maintaining our memory, preventing diseases, supporting our immune systems, and overall physical and mental well-being. Dr. Smith not only talks about male hormones but also explains the interconnectedness of male and female hormonal health. Alongside hormone replacement for men, she delves into the role of estrogen, progesterone, testosterone, DHEA, cortisol, and thyroid hormones in the body.

Importance of Hormones

Hormones help us think clearly, feel good, and remain motivated. Aging naturally affects hormone levels, but several factors like the environment, toxins, and stress can disrupt hormonal balance. As Dr. Smith points out, many men in their 30s now have low testosterone levels, which used to be uncommon. This hormonal imbalance influences our physical health, mental clarity, and energy levels.

Estrogen's Role in Men

Though predominantly seen as a female hormone, estrogen is also present and necessary in men. It supports memory, bone structure, and prevents erectile dysfunction. However, Dr. Smith warns that too much estrogen in men can increase the risk of heart disease and prostate cancer. It's crucial for men to maintain estrogen at normal levels, neither too high nor too low.

Understanding Progesterone and Testosterone

Progesterone in men supports nerve health and hormone balance. It also helps prevent high levels of dihydrotestosterone (DHT), which can enlarge the prostate and increase heart disease risk. Testosterone is misunderstood as just the sexual interest hormone. Dr. Smith emphasizes that it is essential for energy, muscle mass, lowering cholesterol, and supporting overall mental health.

The Impact of Aging and Toxins on Hormones

As we age, hormonal dysfunction increases due to various external factors. The rise of toxins like BPAs and microplastics affects testosterone levels. Julie highlighted surprising statistics: a woman who breaks a hip has a 50% chance of not walking for a year, and a man, 50% chance of dying within a year, underscoring the seriousness of bone health in men which is influenced by hormones.

Personalized Medicine Approach

The power of personalized medicine cannot be overstated. Unlike conventional treatments, personalized medicine precisely targets individual needs for optimal health results. The science Dr. Smith practices tailors for individuals— as evident with hormones, where no two patients receive identical treatments. This approach ensures balance in hormone replacement and nutrition.

The Importance of Thyroid and Insulin

Dr. Smith outlines the importance of the thyroid, the "conductor" organ for our entire system. Insulin balance is paramount too. High or low levels are common, but the key markers, like fasting blood sugar and insulin levels, are crucial for preventing diabetes, heart disease, and certain cancers. The connection between testosterone regulation and insulin balance was also elucidated.

Resources from Dr. Pamela Smith

Mark as Played
Transcript

Episode Transcript

Available transcripts are automatically generated. Complete accuracy is not guaranteed.
(00:00):
Probably the most importanthormone in the body is thyroid,

(00:04):
because thyroid regulateseverything in the entire system.
And that one, you haveto get perfect, optimal,
and not just normal.
Oh, I will be 71 in July.
I do not plan on retiring.
This is my natural color ofhair, so I, I'm gonna go for it.
I plan on being not just 100,but a healthy 100 years of age.

(00:27):
70 honestly is young, butit's only young if you
are hormonally balanced.
We never saw a male under42 with low testosterone,
and now we're seeing men thatare 30 with low testosterone.
and Without testosterone, it isreally hard to compete in a very
intense corporate environment.

(00:50):
Thank you so much for, we're doingthis episode here, Dr. Pamela Smith.
It's an honor to have you here.
I know you're busy.
I. You're, you're always writingbooks and, but today we're
gonna focus in on a, on a veryimportant topic on male hormones.
But also this will, um, the womenthat are listening, you know, if

(01:10):
there're men in your life, uh, Imean, it's very important, but also
I'm sure you know Dr. Pam, that,uh, women will also get something
from this, this chat as well.
So thank you.
absolutely.
Hormones are importantto both men and women.
Besides, if you fix him,you've gotta fix her.
If you fix her, you have to fixhim, so it goes hand in hand.

(01:31):
That's right.
That's why, that's why I figured,and you know, like we were talking
right before we recorded, there's a,well, there's a lot of things that
affect us as humans, but you know,as a lot of us are entrepreneurs,
most of us, unless you're kindof thinking about jumping into
business for yourself, then you're.
Uh, I hate to say the entrepreneur'cause I, I don't know, like that
term, but, you know, whatever it is.

(01:53):
But, uh, there's other factorsat play that make us us, that
help us think straight, uh,feel good and stay in the game
because that's the whole point.
It's like, how do we dothis for us and feel great,
have a good time doing it?
Oh, I will be 71 in July.
I do not plan on retiring.
This is my natural color ofhair, so I, I'm gonna go for it.

(02:14):
I plan on being not just 100,but a healthy 100 years of age.
Right on you and Dr. Savage too.
I mean, like he's, he, well,he's come outta retirement,
I think a couple times.
You guys are, justto call it to him.
Um, he's a colleague of yours,good friend Dr. Paul Savage,
who's been on this podcast too,
Yeah, Savage and I have knowneach other for our ER days

(02:37):
back at Detroit receiving, andthen as we moved into more of a
personalized medicine approach.
both of you individuallyand collectively are
doing some amazing things.
I'm honored that I'm get to, like,I, I get to see the first, you know,
hand look at some of, you know,just the, the knowledge that you're
sharing out there and publishing.
And, uh, I will actually be gettingsome of the, the treatments that Dr.

(03:00):
Savage is doing very soon.
Soon to be i'll.
I'll report that onthe podcast later.
I think this is the first timeI've even said that, so, yeah.
Yeah, I will.
But so how, let's just cut rightto the topic and then I think
then we'll kind of sneak backa little bit on your background
and, and, you know, and someof the other nuances there.

(03:20):
But, but hormones, why, whyare they so important and what
are they, let's start there.
That's a great question.
So first of all, why arehormones important and
hormone replacement for males?
Uh, we commonly think aboutit for women, but for men
it's equally as important.
When it comes to memory, you needhormones, so we're gonna go through

(03:41):
each hormone and discuss it.
When we look at prevention ofheart disease, uh, that is very
important when it comes to hormones.
When we look at the immunesystem, when we look at bone
structure, uh, believe it or not,men can actually get bone loss.
So it's really important tolook at it from that viewpoint.
Uh, when we look at it from theviewpoint of depression and anxiety,

(04:04):
I mean, there's many reasons.
Um, muscle mass, energy levels.
There's so many reasonsto look at male hormones.
So it's important.
So let's start looking at 'em.
We'll start with, believe it ornot, estrogen, because that's
the one we never talk about.
Um.
predominantly at least seen asthe the female hormone, right?

(04:25):
It is, but men do make allthree estrogens that women make
E one, E two and E three andmen need estrogen to maintain
bone structure and for theirmemory, uh, they also need it to
prevent erectile dysfunction, ed.
Uh, so it's a reallyimportant hormone.

(04:46):
But if estrogen is too high,it increases a male's risk of
heart disease and increaseshis risk of prostate cancer.
And so we want to measurethat hormone because we want
a dead center of normal,not too high, not too low.
Perfect.
And the science is actuallyhere so that it can be
perfect for every man.

(05:09):
Uh, men also make progesterone,again, a hormone more commonly
discussed with women becauseof anxiety, et cetera.
But progesterone is importantfor men for myelination,
Hmm.
so their nerve endings stay.
It also is a great five alphareductase inhibitor, which means

(05:29):
that it really helps balancesome of the other hormones in the
body, like dihydrotestosterone,the other testosterone.
I've heard of that.
Yeah.
and we don't want DHT to be highbecause then the prostate gets big.
You have an increased risk in heartdisease, an increase in prostate
cancer as well, and so progesteroneis just a great balance for that.

(05:53):
Plus, the newest studies areshowing that it helps the brain.
In fact, we are using IVprogesterone in both men
and women for a traumaticbrain injury IV in the er.
Oh, wow.
And that's a, I know that'sa bigger topic lately at TPE,
or not TPEs, but traumaticbrain injuries, TB eyes,

(06:15):
is a huge issue.
And so we're now usingit for that as well.
Uh, and then of course themale hormone testosterone.
Yes, it is sexual interest.
But it also lowerscholesterol, blood sugar,
blood pressure is memory, isthe immune system is energy.
I mean, fights, depression,anxiety, muscle mass.

(06:38):
It has so many fabulous functionsin the body that without it,
that's part of how people age isthat they really don't have it.
So is it the hormones?
And, and maybe this is, howdoes, how does it all work?
Because we, what, we start offwith our own metric or levels
of hormones, but then thingshappen throughout life, right?

(07:01):
Out of the aging process, there'ssome hormonal dysfunction, but
that's for a number of reasons.
People tend to have lower hormones.
With age, but now newly, sinceabout 2017, we are now seeing very
young men with low testosterone.
It was, it did not reallyhappen before then.

(07:23):
We never saw a male under 42with low testosterone, and
now we're seeing men thatare 30 with low testosterone.
Some of it is related to COVID-19.
Uh, some of it is related totoxins in the environment.
And so there's just a buildup ofso many toxins now including, uh,

(07:45):
hormone disrupting things likeBPAs, uh, that are part of plastics,
et cetera, um, that they causetestosterone to be low, uh, a lot.
Uh, and so you need that hormonefor bone structure as well.
Uh, so men want to not fall.
In fact, the stats for men are worsewhen they break a hip than women.

(08:08):
When a woman falls and breaks ahip, one half, do not walk for a
year when a man falls and breaksa hip, one half die within a year.
Wow.
Just from what?
Being not able tomove around and do.
Wow.
It's really much more serious andwe don't spend enough time talking

(08:30):
about bone structure in men.
It because it is something thatis a preventable disease process
in almost every single male.
But men do need bone density testsstarting at 60 or 65 years of age.
because I'm thinking of myaudience right here and myself.
I just turned 40 and I. Thestats that I have, and this is
why we're talking about peopleare like, why men and not women?

(08:53):
Well, it's like about 75% of folksor so are men who listen and watch,
uh, this podcast, this show, butalso I know it, it's 40 and up.
It's more like 45, maybe 50 iskinda like the sweet spot and
you know, the most people are,are listening and watching.
Well, and without testosterone,it is really hard to compete in a

(09:15):
very intense corporate environment.
I mean, I still work 18 hours a day.
I can only do thatbecause I have hormones.
I still speak on fourdifferent continents.
As you've seen, I, I'vewritten numerous books.
Just have a brand new book onhow to prevent breast cancer
and how to prevent a recurrence.
Uh, that just came out.

(09:35):
I'm still going really strongdoing the research with Dr. Savage
when it comes to therapeuticplasma exchange and getting
rid of toxins in the body.
So, 70 honestly is young,but it's only young if you
are hormonally balanced,and it is all about balance.
So you have these two other hormonesthat we don't talk about a lot,

(09:58):
either called DHEA and cortisol.
Those are made in the adrenalglands, the glands that sit
above the kidneys, but DHEAinterfaces because it makes
estrogen and testosteroneand a balances cortisol.
The stress hormone,
Mm-hmm.
lovingly call theanti-aging hormone.

(10:19):
It is the longevity hormonebecause it gives you energy and
your immune system and lowerscholesterol, and you feel so
invigorated when you take it.
It is absolutely fabulous,but we only give it to
people that it is low in
Uh.
and it does balance cortisol,the stress hormone, which is

(10:39):
a very interesting hormone.
You have to have cortisol to live.
If you do not have it,you die within a week.
So it's the most important hormonein the entire body, and they
all come from another hormonecalled Pregnanolone, and I'm
gonna spell that because it'shard to say and hard to spell.

(11:00):
It's P-R-E-G-N-E-N-O-L-O-N-E,so P-R-E-G-N-E-N-O-L-O-N-E.
Which makes all thehormones that I discussed.
Plus it is your hormone of memory.
And even if you're 45,if you're really, really

(11:22):
stressed, the body has to makecortisol so the body will take
pregnenolone and make cortisol.
So you can have low prednisoloneeven if you're 45 years old, and
you'll have brain fog and notrapid fire memory, which is not
great at a corporate environment.
You really want to be ableto compete at your best
level, and so pregnenoloneis equally as important.

(11:47):
All the hormones I talked aboutare best measured by saliva,
except for pregnenolone is byblood, and the golden number
for pregnenolone is 50 or above.
And again, we only replace itin people who need it, even
though I'll be 71 in July.
My pregnenolone level's 55,so I don't take pregnenolone.

(12:08):
I still have that hormoneand, and everybody's
really, really different.
And that's the reason whypersonalized medicine is the
best medicine there is becauseit is a personalized approach.
We look at the cause of the problemand not just treat symptoms.
Oops.
Well, let's, and let'spause there for a moment.
'cause that is a key thing thatI know you and Dr. Savage really

(12:29):
stress is personalized medicine.
And I've.
I, I've been fortunate enoughthis podcast is honestly a
shortcut or a hack to, to meet alot of people in, in all spaces.
But ironically, I've come across alot of, um, you know, personalized
medicine type folks like yourselvesand, uh, but lately even more

(12:50):
so because of me getting olderand just understanding, wow,
all these things that, you know,very toxic environment right now
that a lot of us are living in.
But I feel like my age group.
Maybe even more so becausefrom the very beginning, and
maybe that's something we talkabout, but uh, just like you

(13:11):
were saying to continue intothe later years at 40 and later,
I'm just talking about myself.
I. It's like, what can we do?
What, how can I personally,you know, measure what's
going on inside of me and thenactually have action steps now.
Because if you don't measure, it's,Dr. Savage talked about this, like
get the data and then it's like,whatcha gonna do with that now?

(13:33):
And that's what I really love.
It's not a generalblanket statement.
Like, yeah, okay, takethese vitamins or do
these things, you know?
But no, actuallyunderstand your data.
And.
maybe can you talkon that a little bit?
Your
Absolutely.
It's really differentfor every person.
And AI is here to stay.
I ra people that it's notgoing to take over, uh, from a

(13:55):
personalized medicine viewpointbecause it really is personalized
and customized to every patient.
Uh, but when it comes to thathormone pregna, when I, I talk to
Siri instead of typing it in, Iusually will talk to her and say.
And be saying pregnenolone,she types pregnant alone.

(14:15):
So I don't think AI is gonnatake over the world quite yet.
Well, Siri's not, not she.
She's not thesmartest, or it is not.
Yeah.
no, she can't learn yet.
Even though I've probably saidit 300 times into my new cell
phone, she still can't learn.
But it really is a customizedapproach to every person.
That's where the science.

(14:36):
Is here.
In my own personal practice, thereare no two patients that get the
same hormones, male or female.
And so all these patients,they're all different.
The hormones are compounded,they're made individual for each
person, and men are a little easierto give hormones to than women.
They tend to have less side effects.

(14:56):
There's a, a wider, whatwe call therapeutic range.
So they're a little bit easierto give hormones to than women.
Women.
You have to get perfect.
It has to be exactly perfectlybalanced in order for them to
be healthy and stay healthy.
Got it.
Okay.
So Preg, Danone, and, and I,I, as I'm, and just so you know

(15:19):
what I'm doing on the side, Iuse a tool called perplexity.ai
and it's a great search tool.
It's, you know, and, and there'sa whole medical aspect to
it too, but I'm just readingit here as you're saying.
So thank you for spellingit out for me earlier.
'cause I found it like that.
But yeah, it, it basicallysays the precursor to all the

(15:39):
other steroid hormones in thebody, including cortisol, DHEA,
progesterone, testosterone.
So it's like, yeah, ifyou don't have that right,
then you're in trouble.
Right?
Or like, things areoutta balance, at least.
They are out of balance andit is all about balance.
pregnenolone comes from cholesterol,and I have a hard time with

(16:00):
cardiologists understanding this.
Even functionalmedicine cardiologists.
Because you have to havea total cholesterol of
one 40 to make pregna.
Honestly, high cholesteroldoes not cause heart disease.
Inflammation of cholesterolcauses heart disease, and
that's how a statin drug works.

(16:21):
A statin drug is ananti-inflammatory agent, but if
you get the total cholesteroltoo low, then you'll get brain
fog because then you won't makepregnenolone to make all those
other hormones in the body.
So that golden number is totalcholesterol one 40 in order
to make the other hormones.
Well, and you mentioned 50, right?

(16:41):
As being kind of the, themark for, for pregnenolone.
Uh.
Let's see, what would you, yeah,I don't wanna say recommend, but
like, it's personalized medicine,so I kinda wanna get to like
really knowing your numbers, right?
Like what are the things yousuggest to us watching, listening
should be doing at this phase?
Just to understand, okay, here'swhere we're at, you know, in

(17:03):
terms of hormones and then,and then, you know, we can talk
about maybe potential next steps.
Absolutely.
I wanna refer people to, if youwanna read about male hormones to my
book, maximize Your Male Hormones.
Uh, which obviously youcan get on Amazon, probably
the easiest location.
But in that book it discusses theother hormones that interface.

(17:27):
Because it really, theydo kind of weave together.
Probably the most importanthormone in the body is thyroid,
because thyroid regulateseverything in the entire system.
And that one, you haveto get perfect, optimal,
and not just normal.

(17:47):
And conventionally, a medicinenormal is okay, but in a
personalized medicine approach,you want it to be perfect.
So let's talk about somenumbers since you asked.
Okay.
So people grab yourtablet out there.
Okay.
Or, or a piece of paperif you're like me.
And write it down.
So your body makes t, SHthyroid stimulating hormone.

(18:09):
The hormone that stimulates thyroidperfect is the lower limit of
normal, which is about 0.35 to two.
Uh
The higher you go, thenthe worse the function is.
And then you can be hypothyroidor have low thyroid function.
The body makes T three and T four,which are two thyroid hormones.

(18:31):
You want those to be dead, center ofnormal, and these are blood studies.
You measure the free form.
The trouble isconventionally a medicine.
We never measure the T three.
The T three is the one thathelps prevent heart disease.
It's part of the mitochondria,the engines in the body.
So really important measure.

(18:51):
As is reverse T three, whichlooks at store thyroid and
thyroid antibodies to see ifyour body's producing antibodies
against its own thyroid gland.
So you have thyroid.
It is the conductor, literallyof the hormonal symphony.
Hmm.
Equally as important is insulin.
Insulin is the hormone thatregulates your blood sugar.

(19:16):
80% of people that areadults in the United States.
Have insulin.
That is not perfect.
So let's look at those numbers.
Okay, so perfect fasting bloodsugar for everybody out there.
If you're under theage of 60 is 70 to 85,
Okay.
if you're from up to age 60, 70 to85, 60 and above, it's 70 to 90.

(19:43):
So as you age, itcreeps up a little bit.
70 to 90.
Anything above 90, you aregoing down the wrong road.
Why wait until you're diabetic?
Why don't we do somethingto regulate your insulin
before that time?
The trouble is unless you see apersonalized medicine practitioner,

(20:04):
you probably have never hadyour insulin level measured.
So perfect.
Fasting insulin is six toohigh or too low is not good.
And then you probably all, everybodyout there has measured hemoglobin
A1C, and the perfect there is 5.4.
And so you want that oneperfect because insulin

(20:26):
regulates blood sugar.
If your blood sugar's notperfect, not only do you have
an increase in getting diabetes,but heart disease, stroke, every
cancer there is and memory loss.
So hugely important, you haveto have your blood sugar and
that hormone, insulin normal.

(20:47):
The American Endocrinology Societysaid the following, and it's now
published, that one of the best waysfor men to normalize their insulin
is to make sure their testosteroneis normal at their testosterone,
is not to look at hormonereplacement therapy as a mode of
regulating insulin in the body.
Wow.
That just got published.

(21:08):
Uh, it, it, it is veryinteresting to look at.
They really do all weave together.
Yeah.
Well, wow.
Thank you for layingout all the numbers.
Are, are there some more, or arethose the, the main ones there
That's the main ones to look at.
But there is also melatonin, andit's not just your sleeping hormone.
Melatonin is part ofyour immune system.

(21:31):
In fact, we even use melatoninnow to treat different kinds of
cancers like breast and prostate.
Uh, so that one's measured by salivaat eight in the morning, 5:00 PM
and 3:00 AM with the lights off.
So too much melatonin's back.
That's why we measure, uh,melatonin and serotonin

(21:53):
are in the same pathway.
Uh, probably everybody'sheard about serotonin.
The happy neurotransmitter.
Uh, so if you have too muchmelatonin, then serotonin goes too
low, so we want melatonin to bethat perfect golden number as well.
It really is a balance.
I mean, it's like, yeah, andthat's why without measuring
any of this, how would youknow what you're doing?

(22:14):
I mean, you
and
You wouldn't, andthat's the trouble.
And, and I thank you for invitingme to be on your podcast,
because there are so many peoplethat go to a practitioner and
they don't measure hormones,or they measure them by blood,
or they measure them by urine.
And as you saw, some ofthese are measured by blood.
But the big ones, estrogen,progesterone, testosterone,

(22:37):
DHEA, cortisol melatoninare all measured by saliva.
And, and you're very welcome.
And I'm happy and honoredyou're here and taking the time.
'cause I know, like you're,you're, you're very busy.
You're speaking all over the place.
And I really have made a pushfor this podcast for at least a

(22:57):
decent number of episodes hereand there to focus on health and,
and like, just looking at myself,looking at friends around me.
I'm sure those of you listeningand watching have been affected
by people, uh, maybe yourself, butyou have friends and family who.
Maybe got sick too early or cancersor, you know, all these, that's why
I'm talking with Dr. Savage a lot.

(23:18):
And, and I'll just say it righthere, you know, him and I, and
you're also involved in there is theTPE Blueprint podcast that is either
released or will be very soon.
Uh, but when this goes out, 'causeI'm, I'm becoming more obsessed with
this concept of like, okay, reallyunderstanding what's in me, but also
what do you do with all of this?

(23:39):
And
Well, that's so, soimportant because it really
is all about inflammation.
A little bit of inflammation heals.
Too much causes every diseaseyou can think of, from heart
disease to colitis to cognitivedecline to cancers, et cetera.
So all the hormones I mentionedare anti-inflammatory.

(24:00):
They get rid of inflammation whenwe do TPE and we get rid of the
toxins out of your body, that isalso getting rid of inflammation,
which is the key component here.
Let's hammer down on that becauseon inflammation as a topic, because
that is something when I understoodthis and I'm understanding even more
so talking with Dr. Savage a lot.

(24:21):
And just for anybody who hasnot listened to Dr. Savage,
he's been on the podcasttwice now, so he's pretty easy
to find, just look him up.
And one was pretty recent and um,but also just a personal story.
Like something that caught me theother day as a friend of mine, he is
like, yeah, he is 40, 41, I think.
He's like, I just can't really payattention at work more than like

(24:42):
four hours at a time, you know?
And.
And I'm sure it's some breaks,but it's just like, it's almost
like days done after four hours.
I'm like four hours.
I'm like, that doesn't seem right.
So, but I doubt he's the only one.
And I know I could go longerthan that, but definitely.
I don't know.
You probably have more staminathan I even do, so I'm sure

(25:02):
it's some inflammation.
Some, yeah.
In and hormones are wrappedup, but I guess let's just
talk about that whole topic.
Um,
Well, it does.
It starts with how you eat, okay?
People always say,well, how should I eat?
No matter who you are, thebest diet is Mediterranean.
Because it's anti-inflammatory.
So that is a great place to starteating a Mediterranean diet,

(25:26):
uh, from the viewpoint of lamb.
Lamb is like the perfect red meat'cause almost Oh it is because
it's the easiest on your stomach,the easiest on your colon.
Almost all of the fat in itis omega threes the good fat.
And so it truly, it's full ofcarnitine, which gives you energy.

(25:47):
So it's huge.
Uh, it's like the perfect thing.
Exercise is key, but peopleneed to understand exercise.
You should exercise threeto four days a week.
If you are an aggressive exerciser,and a lot of my patients are
because I see professionalathletes in my practice,
then your body gets depleted.

(26:09):
Nutrients.
So even if you're 25, 35, 55 or85, if you're playing hockey seven
days a week or you're, you'relifting weights seven days a week
or marathoning, et cetera, thenyour body gets deplete of really
important nutrients at any age.
And so we wanna replenish thosenutrients, and that is also a very

(26:32):
personalized approach to medicine.
You know what I neednutritionally is different than
what other people would need.
And starting at the ageof 50, people do get
deplete in three nutrients.
They get deplete in L-carnitine,which is an amino acid, a part of
the fueling source in the body.

(26:53):
They get depleting coenzyme Q 10,which most people have heard of
nowadays, and they get depletein something called alpha lipoic,
L-I-P-O-I-C acid alpha lipoic acid.
The last two you cannot eatyour way into, but you, those
are all three fueling sources.
So at 50 most people go, well, youknow, I, I, I really feel 50 now.

(27:17):
Because their energy's not the same.
They, their stamina's not the same,their cognition's not the same, but
a lot of that is due to hormones andlack of fueling source in the body.
And so we wanna go back andmeasure all of those very important
nutrients and what people need andmake sure those reactions work.
Again, the science ishere to do all this.

(27:39):
This is not, quoteunquote, rocket science.
The science is here so thatevery single patient can
have this kind of care.
yeah, it's absolutely necessary.
I feel like, like right now,we're, I mean, not only the food,
and I'm just thinking of when I'mtalking with Dr. Savage, you know,
the, just the amount of toxinsnow in everywhere we live and
what we eat, breathe, drink ourhomes being the most toxic place.

(28:03):
I think it's 500 times more toxic,I believe, than anywhere else like.
It's outrageous.
So we're going against alot, I mean, stuff that we
just honestly can't control.
We can control a good amount,but, um, what you said is
like, you gotta, you gottameasure the stuff and actually
know what to do about it now.

(28:24):
And, and my brain's going toinflammation still, but like back
to that because like, that islike the root of everything, it
seems, all the diseases and how
Well it is, and there's reallythree nutrients that everybody
needs to take at any age.
The first is fish oil,which is anti-inflammatory.
Okay, so a thousand milligramsfor most people, make sure

(28:46):
it's pharmaceutical grade.
Pharmaceutical grade meansthat it is free of toxins and
it's bioavailable, meaning itgets into your body and does
what it is supposed to do.
So that's fish oil.
Now I personally take 3000 ' causeI inherited high triglycerides.
That's the fat content.
On your cholesterol test,you see triglycerides.

(29:07):
I inherited a high level,which increases my risk of
heart disease and stroke.
So I take 3000 milligrams aday of fish oil and that keeps
my triglycerides very normal.
So fish oil, probiotics,a multivitamin.
Everybody should start with.
Got it.
Those are the three things,and then we add from there

(29:28):
so that's like thefoundation of everything,
no matter, I mean, honestly.
Just start.
Just start that.
Plus that multivitamin is,for many reasons, the prostate
needs zinc, but in order to maketestosterone, you have to have zinc.
So sometimes it's justreally simple things.
I've had some patients, both maleand female, that they honestly

(29:49):
didn't need testosterone.
They just needed amultivitamin and to eat better.
Okay, so I mean, it doesn'thurt to start there at least.
exactly, and exerciseincreases testosterone.
I have a patient in my practicethat plays aggressive hockey, and
he didn't need testosterone untilhe was 65 because he actually

(30:09):
exercised his way into it.
Are there different types ofexercises for, you know, different
levels of testosterone benefit?
We'll say,
There is it Ha You reallywant a mixture of exercise.
So first of all, exercisehas to be on the ground to
maintain bone structure.
So is bicycling great?

(30:30):
Is swimming great?
Yes, it burns calories, butit doesn't maintain bone.
So at least, you know, oneday of the week you can swim,
but the rest of the time itneeds to be on the ground.
So you're actually maintaining bonestructure when you're doing it.
Uh, so obviously there's othertypes where you're lifting weights,
there's many varieties, but youdo want to have an aggressive

(30:53):
program of all kinds of exercisein your exercise portfolio.
That makes me feel kind of goodbecause I've been doing a lot of
juujitsu lately, so like wrestlingand stuff on the ground, and
it's probably the most groundtype of stuff you could do.
Um, I'll keep it up, but I meanlike, but you said swimming and
biking those, or cycling that's.

(31:13):
So actually really happy yousaid that because a lot of
folks will just default to that.
But you're right, there's notany pressure on your body.
That's why a lot of peopletake it up, you know, is maybe
for joint issues or some kindof rehab, which is great.
It's better than, you know,it's better to burn the
calories that way, but thatmakes sense to have something
on the ground for, for bones,

(31:35):
Absolutely.
what would yourecommend for measuring?
Like do you have, go-to obviouslysomeone who is doing, you know,
practitioner for, um, personalizedmedicine I'm sure would be able
to be a good support, but like ifsomeone wants to test themselves
and understand where they're at andget baselines for all this stuff,
where do you normally have people?

(31:56):
we do and, andeverybody's different.
So what we measure is personalized,but eventually we really want to
look at hormones in everybody.
We really want to look atthe nutritional status, amino
acids, fatty acids, organicacids, all those things in the
body, what your vitamins are.
We do wanna look at toxicmetals and other toxins

(32:18):
like BPAs and phthalates andmicroplastics, et cetera.
We wanna look at your gut health.
It's really important.
That's a stool test.
70% of your immunesystems in your gut.
So if your gut's nothealthy, you're not healthy.
Uh, biotin for hair andnails, 90% is made in the gut.
Your B12 is all made in the gut.

(32:40):
Your vitamin K is made in the gut.
Uh, vitamin K, by the way,is not stored in the body.
Uh, so you have to have a healthygut to, to make all of those things
So, wow.
Actually, I didn't know about that.
Yeah, vitamin K. It's notstored in the body, it's just.
In and out,
that it stays sevendays and then it's gone.
okay, got it.
Well, okay, so where, like, do youhave a, a, a, a way someone would

(33:05):
go about and say like, Hey, I, Ijust want to know this information.
Like what would yourecommend someone go and do?
I.
Uh, the people can goto personalized medicine
certification.com if.
Someone's listening and they'rea practitioner and they want
training, uh, which would befrom a medical school, uh, that
they, so that's one personalizedmedicine certification.com.

(33:28):
I'm happy to share my email.
You're welcome to emailme at faafm63@yahoo.com,
so FAAFM63@yahoo.com.
If you wanna know apractitioner in your area.
You know, happy to share thatwith you, and then obviously you

(33:48):
can go to my website via my name.
Yeah.
Yeah, that's, and we'll linkeverything below, um, you know,
or wherever the show notesor description is for you.
And I'm, I'm thinking I'll probablyput together some kind of notes
too, just because I know it'sa lot of information and very
specific, uh, but obviously yourbook as well, um, to go snag

(34:09):
that over, you know, MaximizeYour Male Hormones on Amazon.
Um, so because I'm just thinking,you know, a, after I learned
information like this, likeI gotta know my own now, I
can't just like hear all thesenumbers and under, you know,
all these names of hormones and.
It's cool to, it's great tounderstand all this stuff.
It's like, now what?
How do we practicallydo something with it?

(34:31):
So,
and it's fixable when youknow, people need to understand
that this is good news.
We can measure it alland we can fix it all.
So for example, when wetalked about estrogen in men.
It breaks down into three estrogens.
Make it nice and simple.
Two, four and 16 hydroxy estro.

(34:52):
Okay, so two, four, and 16.
Two is the good one.
16. You need a little bitof for bone structure.
Four is bad.
If you have four, it dramaticallyincreases the risk of prostate
cancer in a male and in women.
Breast cancer, breast cancer,and prostate cancer are very,
very, very closely tied together.

(35:12):
And so the good news is wecan fix it in every patient.
There are no patients, none thathave to have abnormal breakdown
of estrogen, male or female.
It's a hundred percent fixable.
So a lot of the things we'retalking about today on this podcast
are the sciences here, and we canhelp people be really healthy.

(35:34):
That's pretty incredible.
'cause I feel like with knowingall this stuff, or it becomes
almost like, oh my gosh, what doI do with all of this information?
Or, yeah, it's almost outtamy hands a little bit.
But um, yeah, it's, thescience is here, which I'm
finding is super fascinating.
I mean, you mentioned ai.
I know there's.

(35:55):
You know, once you know someof this information, there's,
there's, um, ways to use AI tohelp guide you a little bit that
way, obviously have a doctor.
Yeah.
Um, but it's, it's, I don'tknow, it's very interesting
'cause I've been getting, youknow, my own toxin test back.
You know, I won't gointo all that now, but.

(36:15):
You know, through Dr. Savage and,and you know, MD Lifespan and
it's, it's pretty incredible.
You know, I've had blood tests done,so some of these levels, I'm gonna
have another one soon, so I'm like,I'll be able to kind of compare,
uh, a lot of what you just said.
Yeah, and almost everybody's toxic.
My grandparents had a farm,so honestly, I never ate

(36:36):
anything that wasn't organic.
Until I was 18 and went off tocollege, and so I only ate organic.
We, we picked everything.
We ended up, you know,freezing it, canning it.
We, we made our own jam.
We did the whole kit and caboodle,but I was really, really surprised
when I did my toxin test to findout that I was high in fungus.
But honestly, I shouldn't havebeen because I stay in a lot

(36:58):
of hotels and places whichcan have had water damage.
It's really important to getthat fungus out of your body.
Uh, so we're discovering thattherapeutic plasma exchange
can help with so many things.
It can actually help people withautoimmune diseases because it
decreases inflammation in the body.
Uh, we're looking at it forwomen before planned pregnancy

(37:22):
to get rid of the toxins.
'cause these toxins do gothrough the breast milk and
they go through the placenta.
Um, there's been a dramatic risein people who've had, you know,
things like autism, et cetera.
Uh, very rare when Iwas in medical school.
Very common now.
Uh, the same thingwith breast cancer.
Very rare prostatecancer now occurring in

(37:45):
people that are younger.
A lot of this is really just toxininduced, but now we have a new way
of getting rid of some of this.
We've been able to get rid oftoxic metals, all of them, except
for gadolinium and aluminum.
We got, could get rid ofsince the mid eighties.
Speculation.
So that's been a great way.
Never could get rid of gadolinium,kind of successful with aluminum.

(38:08):
But the rest we were great.
Now with TPE, we can getrid of gadolinium, almost a
hundred percent in patients.
So we're looking at it for, youknow, prevention of heart disease.
We're looking at it for somany different things, but
it's not TPE by itself.
TPE by itself does not giveyou these dramatic results.

(38:30):
It's TPE plus nutrients.
Uh, so at MD Lifespan, they reallydo a great job in the nutritional
component to all of this.
'cause TPE has been aroundfor 50 years, so TPE plus
nutrients plus hormones, perfect.
But what people need tounderstand is you can't

(38:51):
fix everything at one time.
It's a process.
As much as we'd like to makeevery patient and wave a magic
wand that everything is perfecttomorrow, it is a process.
Anything worth having inlife is a work in progress.
Absolutely.
Yeah.
I mean, like for me, Ithink it's gonna be at least

(39:11):
three to five differentsessions, you know, and, and.
In the way, you know, Dr. Savageexplains therapeutic plasma exchange
as an oil change for the body.
You know, where essentially you're,yeah, you're cleaning out, you know,
the plasma in this case where, wherea lot of the toxins are hiding out.
I. Not all of 'em.
Yeah, I understand.
But you know, you can basically grabthose within, within that procedure

(39:35):
and then you're kind of waiting,little waiting period as your body's
doing its thing, and then you'redoing it again and then again.
And, um, but along with, like yousaid, all the, the vitamins and
other nutrients that are introduced,you know that to a cleaner body.
And this is just mylayman's way to describe it,

(39:55):
And it's funny you should say thatbecause that's, that's an excellent
question sort of response becausethere are some people that can't
take hormones, male and female,and even things like progesterone,
which is basically innocuous.
But they can't take itbecause they're too toxic.
When we do TPE and we get thetoxins out, then they can go

(40:16):
back and take those hormones.
wow.
So it is just your body, what justwill not, does it reject it or?
There's receptor sites for hormones,and so the receptor sites will not
hold onto the hormone properly.
I.
Gotcha.
Okay.
So literally we'll justlike, Nope, not for me.
you know, before we wrap up, likewhat are some of the, now you said
the science is here, but you've beendoing this for a while and you've

(40:39):
known Dr. Savage for a while aswell, you said, what about 40 years?
So you've seen a whole spectrum ofscience and how things are done.
Like what's.
What's on your mind now?
Like where, what's justblowing you away that maybe we
haven't talked about quite yet?
And then like, where do youthink things are going or any,
this is kind of open-ended.

(41:00):
Like any trends that you're justvery, you're paying attention to
that we should be also keeping
biggest trend now for the next 10to 20 years will be toxin removal.
And hormone replacementthat is done correctly.
There's a lot of people outthere that do hormones, but you
can hurt people with hormoneswhen they're not done correctly.

(41:20):
So it is really, really importantthat you see someone that is,
has done a, an either a master'sdegree and personalized medicine
or a certification in personalizedmedicine, so you know that
they were trained properly.
And so my goal, honestly, uh, in thelast part of my career here is to
make sure that people are properlytrained and to make sure that the

(41:43):
public understands that this kindof medicine is not Star Trek.
It's actually here and availablefor everybody, and everybody
does have the right, and theydeserve to have good healthcare.
I, I, and I, and I hope itgoes to, you know, and I think
it's just gonna be spread.
Awareness is like the first thingright is, and that's why we're doing

(42:04):
this right here, is we're talkingabout it, what's possible, what
you should know, and you know, someof these things I. There might be.
Yeah, I, I had to see a, ideallythe, the cost will get lower
for other folks to all be ableto essentially benefit from it.
'cause I know some folks probablywon't be able to, I'm just

(42:25):
thinking in the future, next20 years or so, like things
are gonna change radically asthey always have, you know, so.
I, I think it's perfect timingwith the toxin world that we're
all in and like the more youstart doing some research, 'cause
we've talked about water, uh,on previous episodes here too.
And just like when you startrunning the numbers and seeing
what you're actually drinking,you're like, frightened.

(42:46):
And I'm like, you know,
number one, you do need water,and that's one thing that we
probably don't talk enough about.
People need one half their bodyweight and ounces every day.
On the days they exercise, theyneed another 40 to 60 ounces.
Is because water does detoxify.
But you're right, it reallydoes have to be a very,
very good purified water andoutta glass, not plastic.

(43:12):
right.
Always.
Well, got one right here.
So yeah, no, it's air is anotherthing and there's so many
others, and this is where theDr. Savage episode I did with
him, he lined out a bunch of 'em.
Uh, but now how itrelates to hormones.
This is all new to me, so Dr. PamelaSmith, I, it's, it's been an honor

(43:32):
and I, I'm gonna deep dive into yourbook even more, so I definitely,
you know, I'll link up the linkto Amazon, but maximize your male
hormones is, is available and ready.
If you wanna deep dive, maybemention a couple of the other
books that you think would bealso good for folks to check out.
For women, what you mustknow about women's hormones.

(43:53):
That would be second edition.
Uh, maximize your immune systemif you wanna look at your
immune system, uh, what youmust know about thyroid disease.
If you wanna know about thyroid,I. And then looking at breast
cancer, how to prevent breastcancer before and after.
So it's for people who preventingbreast cancer, but also people

(44:14):
who've had breast cancer.
How to prevent a recurrence.
And you said that'sunfortunately a male, you're
starting to see trends with
are, it used to be that 1%of breast cancer was in men.
It is now 3% is in males, sothat number is rising as well.
Hmm.
Well, I wanna say, and on a goodnote, but at the same time, it is

(44:36):
good to know that there's awareness.
We we're seeing the stats andthere's things that you can do
about everything we talked about.
And truly the science,honestly is here to measure
every single thing and.
A personalized medicine approachis the way to go, not just now,
but 20 and 50 years from now.
Uh, it'll be, we'll be withour little tric quarters from

(44:58):
Star Trek, perhaps doing itthat way, but it will still
be a personalized medicine
That's fine, as long as it worksand it helps everyone else too, so.
Okay.
Well, it's been anhonor chatting and.
I mean, yeah, I felt like mybrain was just wanting to go down
all these little rabbit holes.
So hopefully you're,you're, you, you're like an
encyclopedia and AI yourselfit seems like with 14 books.

(45:21):
I mean, just go check it out, y'all.
It's, uh, and you speak on a lot ofdifferent stages, podcasts and, and
hopefully pretty soon, or you willpretty soon on the TPE Blueprint
podcast that I'm heading up as well.
'cause that's a totalpassion project for me.
So looking
That'll be perfect.
Oh, thank you so much, Joe.
Thank you.
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