JAMA Clinical Reviews
Interviews with expert clinicians and researchers about topics relevant to clinical practice and patient care, including updates in management of common conditions from JAMA, the Journal of the American Medical Association.
Episodes
Type 1 diabetes affects approximately 2 million people in the US and 8.4 million people worldwide. Author Desmond Schatz, MD, of the University of Florida joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of type 1 diabetes.
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Mark Cuban, entrepreneur, investor, and cofounder of the Mark Cuban Cost Plus Drug Company, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the role of pharmacy benefit managers, insurance formularies, and opaque pricing practices that shape how most Americans access prescription drugs. Hear why he thinks doctors are the good guys in a broken system.
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Opioid use disorder is the third most prevalent substance use disorder worldwide. Author Alexander Walley, MB, MSc, of Boston Medical Center and Boston University joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the efficacy, safety, and practical considerations of treating patients with medications for opioid use disorder, opioid withdrawal, and opioid overdose.
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Ovarian cancer may be prevented with removal of the fallopian tubes during pelvic or select abdominal surgery in eligible women. This procedure, opportunistic salpingectomy, can be offered to more eligible women. Author Jurgen M. Piek, MD, PhD, of the Catharina Cancer Institute discusses this and more with JAMA Deputy Editor Linda Brubaker, MD, MS.
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IgA nephropathy is a chronic kidney disease involving deposition of IgA-containing immune complexes in the glomerulus, which often causes kidney failure within 10 to 20 years. Author Michelle Marie O'Shaughnessy, MB, BCh, BAO, MS, of Galway University joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the symptoms, risk factors, diagnosis, treatment, and prognosis of IgA nephropathy in adults.
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Restless legs syndrome is a sleep-related neurologic disorder that causes an overwhelming urge to move the limbs, which can cause substantial sleep disturbance. Author John W. Winkelman, MD, PhD, of Harvard Medical School joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the symptoms, risk factors, diagnosis, and treatment of restless legs syndrome.
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Mifepristone used with misoprostol is the most common abortion regimen in the US. It is also a focal point of reproductive health policy and politics, with controversy over its legal status and regulation by the US Food and Drug Administration (FDA). Author G. Caleb Alexander, MD, MS, from Johns Hopkins discusses this and more with JAMA Deputy Editor Joseph S. Ross, MD, MHS.
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Incidence rates of gastric cancer in younger individuals are on the rise and gastric cancer is the fifth-leading cause of cancer-related deaths worldwide. JAMA Review author Haeseong Park, MD, MPH, from the Dana Farber Cancer Institute, discusses this and more with JAMA Senior Editor Karen Lasser, MD, MPH.
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JAMA Deputy Editor Mary McDermott, MD, and JAMA Deputy Editor Kristin Walter, MD, MS, highlight their selections of top JAMA Clinical Reviews podcasts in 2025.
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In this episode, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Medical News Director Jennifer Abbasi discuss the journal's inaugural Research of the Year roundup.
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Obesity affects more than 1 billion people worldwide and is recognized by the World Health Organization as a chronic, relapsing disease. WHO recently published a guideline in JAMA on the use and indications of GLP-1 therapies for the treatment of #obesity in adults. Francesca Celletti, MD, PhD, and Ezekiel Emanuel, MD, PhD, join JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss.
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Head and neck cancer is the seventh most common cancer worldwide and is commonly associated with tobacco and alcohol use, or human papillomavirus (HPV) infection. Author Lara Dunn, MD, of Memorial Sloan Kettering Cancer Center joins JAMA Associate Editor Margaret Wheeler, MD, to discuss the epidemiology, risk factors, diagnosis, treatment, and prognosis of head and neck cancer.
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Allergic rhinitis affects about 1 in 6 US adults. A recent JAMA Insights summarizes evidence regarding the associations of climate change and air pollution with allergic rhinitis and sinusitis. The discussion includes prevention and management strategies. Coauthor Neelima Tummala, MD, joins JAMA Deputy Editor Mary McDermott, MD, to discuss.
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Clinicians should weigh benefits against risks when engaging patients in informed discussions about cannabis or cannabinoid use. Kevin Hill, MD, MHS, of Harvard Medical School joins JAMA Senior Editor Karen Lasser, MD, MPH, to discuss the current evidence about the therapeutic use of cannabis and cannabinoids in adults, potential harms, and evidence-based clinical guidance.
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Peripheral neuropathy affects approximately 1% of adults worldwide and can be associated with significant disability. Author Michelle Mauermann, MD, of the Mayo Clinic in Minnesota joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss diagnosis and optimal management of peripheral neuropathy.
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Metabolic dysfunction-associated steatotic liver disease (MASLD), an increasingly prevalent condition among adults worldwide, is associated with liver-related complications, hepatocellular carcinoma, and certain extrahepatic cancers. Author Norbert Stefan, MD, from the University Hospital of Tübingen in Tübingen, Germany, discusses this and more with JAMA Deputy Editor Kristin Walter, MD, MS.
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The JAMA Summit on Firearm Violence convened 60 thought leaders from a wide array of disciplines to chart a roadmap that could lead to substantial reductions in firearm harms by 2040. Frederick P. Rivara, MD, MPH, of the University of Washington joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the Summit and steps that could lead to a safer world by 2040.
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Keratinocyte carcinomas, which include basal cell carcinoma and squamous cell carcinoma, are common forms of skin cancer. Approximately 5.4 million keratinocyte carcinomas are diagnosed in the US annually. Author Mackenzie R. Wehner, MD, MPhil, of the University of Texas MD Anderson Cancer Center joins JAMA Associate Editor David Simel, MD, MHS, to discuss treatment of these types of nonmelanoma skin cancer.
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Lung cancer in nonsmoking individuals is increasing worldwide and currently accounts for 15% to 20% of lung cancer cases globally. Benjamin Solomon, PhD, of the Peter MacCallum Cancer Centre in Melbourne, Australia, discusses the epidemiology and treatment of lung cancer in nonsmoking patients with JAMA Deputy Editor Kristin Walter, MD, MS.
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Syphilis infections have increased in the US and worldwide over the past decade. Left untreated, syphilis can cause blindness, deafness, psychosis, dementia, and peripheral nerve damage, and can cause congenital syphilis. Author Franco Chevalier, MD, MPH, from the San Francisco Department of Public Health discusses this and more with JAMA Deputy Editor Preeti Malani, MD, MSJ.
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