JAMA Clinical Reviews

JAMA Clinical Reviews

Interviews with expert clinicians and researchers about topics relevant to clinical practice and patient care, including updates in management of common conditions from JAMA, the Journal of the American Medical Association.

Episodes

September 24, 2025 15 mins

Health care professionals often use numbers to guide decisions, monitor patient health, and communicate information. Author Angela Fagerlin, PhD, of the University of Utah joins JAMA Senior Editor Anne Cappola, MD, ScM, to discuss how providing numerical information may be helpful in shared decision-making with patients.

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Superficial vein thrombosis (SuVT) is characterized by thrombus formation in the superficial veins, typically in the lower or upper extremities. In this podcast, the coauthor of a JAMA review on SuVT, Behnood Bikdeli, MD, MS, discusses pathophysiology, risk factors, diagnosis, and treatment of SuVT with JAMA Deputy Editor Mary McDermott, MD.

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September 3, 2025 13 mins

Untreated hypothyroidism can cause serious health complications such as heart failure and myxedema coma. Author Maria Papaleontiou, MD, of the University of Michigan joins JAMA Senior Editor Karen Lasser, MD, MPH, to discuss the current evidence regarding the epidemiology, diagnosis, clinical presentation, and treatment of primary overt hypothyroidism in nonpregnant adults.

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Interview with Alexander Chern, MD, author of Over-the-Counter Hearing Aid–Enabled Earbuds—Merging Hearing Health and Technology. Hosted by Paul C. Bryson, MD, MBA.

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The incidence and prevalence of cutaneous melanoma in the US and worldwide have increased over the last 5 decades. JAMA Review Author John Kirkwood, MD, discusses the epidemiology, risk factors, treatment, and prevention of melanoma with JAMA Deputy Editor Kristin Walter, MD, MS.

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Hemorrhoidal disease, pathology of the tissue lining the anal canal, affects approximately 10 million individuals in the US. Author Jean H. Ashburn, MD, of Wake Forest University School of Medicine and JAMA Senior Editor Karen E. Lasser, MD, MPH, discuss the current evidence on the epidemiology, pathophysiology, diagnosis, and treatment of hemorrhoidal disease.

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Dalbavancin, a long-acting IV lipoglycopeptide, may be an option for the treatment of complicated Staphylococcus aureus bacteremia without requiring long-term IV access. Author Thomas L. Holland, MD, MSc, from Duke University School of Medicine discusses key points of the DOTS randomized clinical trial and more with JAMA Deputy Editor Preeti Malani, MD, MSJ.

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August 11, 2025 17 mins

Prostatitis affects approximately 9.3% of men in their lifetime and includes acute and chronic bacterial infection and nonbacterial chronic prostatitis with chronic pelvic pain syndrome. Author Minh N. Pham, MD, from University of North Carolina School of Medicine discusses this and more with JAMA Deputy Editor Mary M. McDermott, MD.

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August 7, 2025 16 mins

Geroscience aims to define and modify biologic pathways associated with aging and age-related diseases. Author Stephen B. Kritchevsky, PhD, of the Wake Forest University School of Medicine and JAMA Deputy Editor Mary M. McDermott, MD, discuss current evidence regarding geroscience, human health, and promising therapies that may slow aging and age-related decline.

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New medications for obesity, such as semaglutide and tirzepatide, are highly effective but can be associated with adverse effects that reduce adherence. Obesity expert and author Robert Kushner, MD, joins JAMA Deputy Editor Mary McDermott, MD, to discuss a recent JAMA Insights article on managing adverse effects of obesity medications.

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A patent foramen ovale (PFO) is present in approximately 25% of all adults. Author David M. Kent, MD, MS, of Tufts Medical Center and JAMA Associate Editor David Simel, MD, MHS, discuss how to evaluate the likelihood that a PFO was causal in a patient with a cryptogenic ischemic stroke, and closure of a PFO to lower the incidence of recurrent strokes for affected patients.

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Approximately 200 000 people are hospitalized for diverticulitis each year in the US, and the incidence of diverticulitis is increasing, particularly among younger people. Author Anthony Charles, MD, MPH, of the University of Vermont and JAMA Deputy Editor Mary M. McDermott, MD, discuss current evidence regarding the epidemiology, diagnosis, and treatment of diverticulitis.

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A recent Review discusses the epidemiology, risk factors, diagnosis, and treatment of ovarian cancer. William Cliby, MD, and John Weroha, MD, PhD, both from the Mayo Clinic in Rochester, Minnesota, discuss this and more with JAMA Associate Editor Margaret Wheeler, MD.

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July 17, 2025 24 mins

Early-onset gastrointestinal cancers, typically defined as occurring in patients younger than age 50, are increasing worldwide. A recent JAMA Review summarizes current data on early-onset colorectal, pancreatic, and esophagogastric cancers. Coauthor Kimmie Ng, MD, MPH, of Dana-Farber Cancer Institute joins JAMA Deputy Editor Kristin Walter, MD, MS to discuss.

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Approximately 40% of men older than 50 have urinary frequency or urgency that affects their quality of life. Author John T. Wei, MD, MS, of the University of Michigan Department of Urology and JAMA Deputy Editor Mary M. McDermott, MD, discuss diagnosis and management of these symptoms in older men.

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July 7, 2025 14 mins

In the 25 years since its emergence in the US, West Nile virus has become the leading cause of domestic mosquito-borne disease. It causes approximately 1300 neuroinvasive disease cases and 130 deaths annually in the US. Coauthor Carolyn Gould, MD, of the CDC joins JAMA Senior Editor Karen Lasser, MD, to discuss the review on this topic published in JAMA.

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Worldwide, 1 in 3 women and 1 in 5 men older than 50 years experience osteoporotic fractures in their lifetime. Author Suzanne N. Morin, MD, MSc, of McGill University and JAMA Deputy Editor Mary M. McDermott, MD, discuss the diagnosis and management of osteoporosis.

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Which tests can be used to diagnose type 2 diabetes? When should injectable medications for type 2 diabetes be started? These are just some of the questions clinicians may have when diagnosing and treating type 2 diabetes in adults. Author Rita Kalyani, MD, MHS, of Johns Hopkins University School of Medicine, discusses this and more with JAMA Senior Editor Karen Lasser, MD, MPH.

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June 16, 2025 18 mins

Adrenal insufficiency is a syndrome of cortisol deficiency. A recent JAMA Review summarizes the pathophysiology, diagnosis, and treatment of adrenal insufficiency and adrenal crisis. JAMA Associate Editor David Simel, MD, MHS, discusses this and more with author Anand Vaidya, MD, MMSc.

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Interview with Anne P. Cameron, MD and Glenn T. Werneburg, MD, PhD, authors of Foley Catheter Management: A Review. Hosted by Amalia Cochran, MD.

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