Johns Hopkins Malaria Minute

Johns Hopkins Malaria Minute

Impactful malaria science, and the trailblazers leading the fight. A podcast from the Johns Hopkins Malaria Research Institute.

Episodes

September 9, 2025 1 min

Feeding mosquitoes L-DOPA can either strengthen their defences against malaria or shorten their lifespan — showing that in vector control, the dose makes the difference

Transcript

As with all medicine, the dose determines whether something helps or harms.

Researchers recently looked at a substance commonly found in mosq...

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How do you turn vast amounts of genetic data into actionable insight – efficiently and accurately? Professor Bryan Greenhouse of UCSF discusses a series of “hackathons” at the Johns Hopkins Malaria Research Institute (JHMRI) that bring together scientists from around the world to tackle one of the biggest challenges in malaria research: analyzing parasite genetics. By developing open-source tools, workflows, and traini...

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Although severe malaria presents in different clinical forms – such as cerebral malaria or severe malarial anemia – a new study reveals that all severe cases have one thing in common: a shared inflammatory signature

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Whilst most cases of malaria are mild, some take a dangerous turn. In severe cases, the malaria parasite can overwhelm the body, disrupting the blood-brain barrier and l...

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Dr. Alexandra Probst discusses a breakthrough in malaria prevention: bed nets coated with anti-parasitic drugs that stop transmission by curing infected mosquitoes.

With Alexandra Probst, former graduate student at Harvard University.

About The Podcast

The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malaria research and to share it with the global comm...

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How next-generation bed nets could stop malaria by killing the parasites inside mosquitoes, not just the mosquitoes themselves.

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Bed nets have long been a cornerstone of vector control. Coated with insecticide, they serve a dual purpose: preventing bites and killing mosquitoes. But what if those nets could do more – not only kill the mosquitoes, but for those they don’t kill because ...

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The extent to which malaria vaccines reduce cases and deaths is a key consideration. But there’s another factor, too.

with Dr. Lemu Golassa, Head of Medical Parasitology at Addis Ababa University.

About The Podcast

The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malaria research and to share it with the global community.

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A recent study in Ethiopia reveals that local malaria parasite strains differ genetically from those targeted by current vaccines, potentially reducing their effectiveness.

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The recent introduction of two malaria vaccines in sub-Saharan Africa represents a major success in global health, and the culmination of decades of research and development. The two jabs – RTS,S and R21 – target...

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The podcast explores the importance of advocacy for malaria research and control. It follows over 120 advocates gathering in Washington, DC, as part of the ‘United to Beat Malaria’ campaign, urging Congress to continue supporting global malaria efforts.

Key topics include:

  • The US President’s Malaria Initiative (PMI), founded in 2005, which...

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With a shortage of entomologists in malaria-endemic regions, could AI fill the gap? We explore VectorCam, an offline tool powered by a Convolutional Neural Network that aims to support local vector surveillance.

with Dr. Soumya Acharya and Sunny Patel of Johns Hopkins University.

About The Podcast

The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impa...

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Can AI identify mosquito species? VectorCAM, a pocket-sized device, uses machine learning to differentiate species with 95% accuracy, enhancing malaria surveillance efforts

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Not all mosquitoes are created equal. Of the more than three thousand species, only a limited number of the Anopheles genus can transmit malaria. Even within that subset, subtle physiological differences affect h...

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For decades, insecticides have shielded us from malaria—but cracks are showing. Resistance is spreading, and environmental concerns are growing. Could a simple pouch of fruit juice with a powerful secret be the breakthrough we need?

with George Dimopoulos of the Johns Hopkins Malaria Research Institute

About The Podcast

The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Inst...

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March 11, 2025 1 min

One of the main ways of controlling malaria is to reduce mosquito populations through insecticides. But the mosquitoes are developing resistance, making most insecticides less effective. What if the answer lies beneath our feet?

Transcript

One of the main ways of controlling malaria is to reduce mosquito populations through insecticides....

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The prevention of malaria depends upon multiple layers of interventions that work together to reduce cases and deaths. But what makes someone decide to sleep under a bed net, or apply an insecticidal cream? What makes one person take up more interventions than another? How influential are government-accredited health experts versus friends and family? 

With András Vörös, an Associate Professor in Quantitative Methods a...

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Malaria prevention depends on the adoption of multiple behaviors –  like sleeping under a bednet and wearing clothes that cover the skin. Researchers find that conversations with people in one’s own social circle are the strongest factors that influence behavior uptake.

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Malaria prevention depends on the adoption of multiple behaviors –  like sleeping under a bednet and wearing cloth...

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Today, the discovery of antibodies targeting a new region of the malaria parasite that could serve as a promising target for drugs and vaccines.

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Scientists discover new antibodies - a promising target for clinical exploration.

Transcript

The currently licenced malaria vaccines and monoclonal antibodies all target a well-known region of the same malaria protein. That protein – the circumsporozoite protein, commonly known as CSP – covers the surface of the parasite as it enters the human skin through a mosquito bite. By targeting CSP, th...

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We focus on drug resistance and the troubling news that the frontline drug against malaria, artemisinin, is failing due to resistant parasites in severe cases of malaria, and how the collective efforts of drug development – and the data produced – could be used to build an AI chatbot capable of predicting resistance before it strikes.

With Robert Opoka and Elizabeth Winzeler.

About The Podcast

The Johns Hopkins Malaria...

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