Timeline: Get 10% off Mitopure, clinically proven to boost mitophagy. Go to timeline.com/vanessa.
In this powerful episode of The Optimal Protein Podcast, host Vanessa interviews Dr. Dominic D’Agostino, one of the world’s leading researchers in ketogenic science and metabolic therapy.
They dive into how ketones not only serve as a powerful fuel source but also act as metabolic signaling molecules that promote fat loss, protect muscle, and support whole-body health.
Dr. D’Agostino shares why he personally pursues ketosis every day, how ketones interact with protein metabolism, and the key differences between nutritional and exogenous ketones. You’ll also learn how a high-protein ketogenic diet supports appetite regulation, body recomposition, and metabolic flexibility—especially for women in midlife.
If your goals include burning fat, preserving lean muscle, and optimizing energy and cognition, this episode is a must-listen.
🔍 Topics Covered:
• How and why Dr. D’Agostino gets into ketosis every day
• The truth about protein on a ketogenic diet
• Ketones and their impact on muscle protein synthesis and preservation
• Appetite suppression and satiety in a keto-adapted state
• Exogenous ketones: how and when to use them
• The synergy of strength training, protein, and ketones
• Why you test breath acetone ketones
• What the latest science says about ketosis for performance and metabolic health & the future of ketone research in aging, and more
Get 20% off on the Tone Device breath ketone analyzer OR the Tone LUX Crystal Red Light Therapy Mask Ketogenicgirl.com with the code VANESSA
Join the Community! Follow Vanessa on instagram to see her meals, recipes, informative posts and much more! Click here @ketogenicgirl
Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast.
🔗 Connect with Dr. D’Agostino:
• Website: https://www.ketonutrition.org
• Instagram: @dominic.dagostino.kt
• Twitter/X: @DominicDAgosti2
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com
On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!