IGF-1 (Insulin-Like Growth Factor 1) has emerged as a hot topic in health and nutrition discussions, often linked to longevity, cancer risk, and metabolic health.
On one hand, IGF-1 is essential for growth, repair, and metabolic regulation; on the other, it is sometimes associated with disease processes, including cancer and cognitive decline.
For those intrigued by the intersection of nutrition, biomarkers, and disease prevention, IGF-1 offers an opportunity to explore how science grapples with these complexities.
Claims about manipulating IGF-1 through dietary changes — whether by reducing protein or adopting fasting protocols — are common. But does the evidence support these claims?
If you’re curious about IGF-1 and the relationships between diet, disease, and healthy aging, in this Premium-exclusive episode Danny and Alan discuss this fascinating topic.
To listen to the full episode, subscribe to Sigma Nutrition Premium
Timestamps
- [02:21] IGF-1 and Diet: Examining the Relationship
- [09:15] IGF-1 as a Biomarker: Challenges with Sensitivity and Specificity
- [11:54] IGF-1 and Cancer Risk: Insights and Complexities
- [25:51] IGF-1 in Aging: Cognitive Function and Longevity Considerations
- [43:38] Key Takeaways: IGF-1, Diet, and Practical Advice
Related Resources
- Join the Sigma email newsletter for free
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- Enroll in the next cohort of our Applied Nutrition Literacy course
- Murphy et al., 2020 – observational and Mendelian randomization analyses
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